Translational Immunology

Medicine 3

Head of Department:
Prof. Dr. med. univ. Georg Schett

Regulative mechanisms of the innate and the adaptive immune response

Head: Prof. Dr. med. Gerhard Krönke

Insights into basic principles of immunity are a key for the better understanding of autoimmunity and inflammation. Simultaneously, they allow the development of new therapeutic strategies for autoimmune and chronic inflammatory diseases.

Our lab studies molecular mechanisms that link innate and adaptive immunity and thus influence inflammation, tolerance and autoimmune responses. Our aim is to understand key decisions points that trigger a physiological immune response or cause autoimmunity (e.g. rheumatoid arthritis and systemic lupus). At a cellular and molecular level, we focus on the role of myeloid cells (e.g. macrophages, dendritic cells and granulocytes) and study their interaction with cells of the adaptive immune system (T- and B-cells). We are especially interested in the underlying molecular events, which involve changes in the biophysics of cellular membranes as well as the immunological role of cytokines, lipid mediators and nuclear receptors.

 

Selected publications of Prof. Dr. Gerhard Krönke

 
Contact
Prof. Dr. med. Gerhard Krönke MHBA
business card

Staff:

Gerhard Krönke
Jochen Ackermann
Christina Böhm
Katrin Palumbo-Zerr
Carina Scherbel
Tobias Rothe
René Pfeifle
Stephan Culemann
Maria Faas
Fenja Schröder
Jule Taubmann
Brenda Krishnacoumar
Martin Stenzel
Jean-Philippe Auger
Cornelia Stoll
Monica Pascual Mate
Rossella Mancuso
Rita Weinkam
Alexandra Klej (Elternzeit)
Hilal Garibagaoglu
Rachel Sworn