Allergies

Medicine 3

Head of Department:
Prof. Dr. med. univ. Georg Schett

Allergies

Release reaction of a mast cell (mastocyte). Mast cells are cells of the body's defence system and are decisive for an allergic reaction. Initial contact with the allergen leads to the formation of antibodies. These bind to the surface of the mast cell and sensitize it for a reaction, so that on second contact with the allergens the mast cell releases the messenger substance histamine.

Allergies are the result of an immune reaction against harmless targets (e.g. pollen, animal hair, insect venom, drugs). They mainly appear on interfaces, i.e. skin and mucous membranes (respiratory tract, intestinal tract).

There are also internal allergies to blood cells and bones, joints and muscles, which are rarely known to the affected persons. Even systemic reactions on different organs are possible.

The high competence of the Clinic for Rheumatology and Immunology ensures qualified diagnostics. Based on the symptoms and the joint discussion of the relevant trigger factors, a diagnostic strategy is developed for the rapid identification of the responsible allergens and the disease-causing mechanisms. This will be supported by the work of an efficient laboratory.

If the most reliable way to remedy the symptoms - avoiding contact with the responsible allergen - is not possible, a disease-related therapy is initiated. Most allergies of the immediate type (e.g. asthma, shock) are accompanied by immunobiological inhibition (tolerance), which begins in the symptom-free interval and continues over a longer period of time (up to several years at longer intervals) to ensure lasting success. In some patients, this can be done with solutions dripping under the lungs.

There are also so-called pseudo-allergies, which are indistinguishable from real allergies by the patient. Aspirin" intolerance is particularly severe. By means of a special laboratory test on living cells, this disease-causing anomaly can be determined from a blood sample in the Department of Internal Medicine 3.

 
information brochure