Medicine 3

Head of Department:
Prof. Dr. med. univ. Georg Schett


Release reaction of a mast cell (mastocyte). Mast cells are cells of the body's defence system and are decisive for an allergic reaction. Initial contact with the allergen leads to the formation of antibodies. These bind to the surface of the mast cell and sensitize it for a reaction, so that on second contact with the allergens the mast cell releases the messenger substance histamine.

Allergies are the result of an immune reaction against harmless targets (e.g. pollen, animal hair, insect venom, drugs). They mainly appear on interfaces, i.e. skin and mucous membranes (respiratory tract, intestinal tract).

There are also internal allergies to blood cells and bones, joints and muscles, which are rarely known to the affected persons. Even systemic reactions on different organs are possible.

The high competence of the Clinic for Rheumatology and Immunology ensures qualified diagnostics. Based on the symptoms and the joint discussion of the relevant trigger factors, a diagnostic strategy is developed for the rapid identification of the responsible allergens and the disease-causing mechanisms. This will be supported by the work of an efficient laboratory.

If the most reliable way to remedy the symptoms - avoiding contact with the responsible allergen - is not possible, a disease-related therapy is initiated. Most allergies of the immediate type (e.g. asthma, shock) are accompanied by immunobiological inhibition (tolerance), which begins in the symptom-free interval and continues over a longer period of time (up to several years at longer intervals) to ensure lasting success. In some patients, this can be done with solutions dripping under the lungs.

There are also so-called pseudo-allergies, which are indistinguishable from real allergies by the patient. Aspirin" intolerance is particularly severe. By means of a special laboratory test on living cells, this disease-causing anomaly can be determined from a blood sample in the Department of Internal Medicine 3.


Hochschulambulanz/Outpatient clinc
Phone: 09131 85-34742
Fax: 09131 85-36448

Privatambulanz/Private clinic
Phone: 09131 85-33363
Fax: 09131 85-34770

Studienambulanz/Study outpatient clinic
Phone: 09131 85-32093

Station B2-2/Inpatient clinic
Phone: 09131 85-33015

Emergency Information

In emergency cases please call the internal emergency department:

Phone: +49 9131 85-35420