Medizin 3

Publications: Dr. rer. nat. S. Frey

Weber M, Homm A, Müller S, Frey S, Amann K, Ries J, Geppert C, Preidl R, Möst T, Kämmerer PW, Kesting M, Wehrhan F: Zoledronate Causes a Systemic Shift of Macrophage Polarization towards M1 In Vivo. Int J Mol Sci. 2021;22(3):
Andes FT, Adam S, Hahn M, Aust O, Frey S, Grueneboom A, Nitschke L, Schett G, Steffen U: The human sialic acid-binding immunoglobulin-like lectin Siglec-9 and its murine homolog Siglec-E control osteoclast activity and bone resorption. Bone. 2021;143():
Adam S, Simon N, Steffen U, Andes FT, Scholtysek C, Müller DIH, Weidner D, Andreev D, Kleyer A, Culemann S, Hahn M, Schett G, Krönke G, Frey S, Hueber AJ: JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function. Sci Transl Med. 2020;12(530):
Haskamp S, Bruns H, Hahn M, Hoffmann M, Gregor A, Löhr S, Hahn J, Schauer C, Ringer M, Flamann C, Frey B, Lesner A, Thiel CT, Ekici AB, von Hörsten S, Aßmann G, Riepe C, Euler M, Schäkel K, Philipp S, Prinz JC, Mößner R, Kersting F, Sticherling M, Sefiani A, Lyahyai J, Sondermann W, Oji V, Schulz P, Wilsmann-Theis D, Sticht H, Schett G, Reis A, Uebe S, Frey S, Hüffmeier U: Myeloperoxidase Modulates Inflammation in Generalized Pustular Psoriasis and Additional Rare Pustular Skin Diseases. Am J Hum Genet. 2020;107(3): 527-538
Frey S, Sticht H, Wilsmann-Theis D, Gerschütz A, Wolf K, Löhr S, Haskamp S, Frey B, Hahn M, Ekici AB, Uebe S, Thiel C, Reis A, Burkhardt H, Behrens F, Köhm M, Rech J, Schett G, Assmann G, Kingo K, Kõks S, Mössner R, Prinz JC, Oji V, Schulz P, Muñoz LE, Kremer AE, Wenzel J, Hüffmeier U: Rare Loss-of-Function Mutation in SERPINA3 in Generalized Pustular Psoriasis. J Invest Dermatol. 2020;140(7): 1451-1455.e13
Hueffmeier UD, Sticht H, Wenzel J, Wilsmann-Theis D, Wolff K, Loehr S, Frey B, Hahn M, Ekici AB, Uebe S, Thiel C, Reis A, Prinz J, Oji V, Schulz P, Kingo K, Koks S, Moessner R, Munoz L, Kremer AE, Frey S: Rare frameshift mutation in SERPINA3 contributes to generalized pustular psoriasis Eur J Hum Genet. 2019;27(): 1366-1367
Wissbrock A, Goradia NB, Kumar A, George AAP, Kuehl T, Bellstedt P, Ramachandran R, Hoffmann P, Galler K, Popp J, Neugebauer U, Hampel K, Zimmermann B, Adam S, Wiendl M, Kroenke G, Hamza I, Heinemann SH, Frey S, Hueber AJ, Ohlenschlaeger O, Imhof D: Structural insights into heme binding to IL-36 alpha proinflammatory cytokine Sci Rep. 2019;9():
Adam S, Simon N, Steffen U, Harre N, Andes F, Mueller D, Culemann S, Andreev D, Hahn M, Scholtysek C, Schett G, Kroenke G, Frey S, Hueber A: JAK-INHIBITORS TOFACITINIB AND BARICITINIB IMPROVE PATHOLOGICAL BONE LOSS IN VIVO Ann Rheum Dis. 2019;78(): 110-110
Adam S, Simon N, Steffen U, Andes F, Mueller D, Culemann S, Andreev D, Hahn M, Scholtysek C, Schett G, Kroenke G, Frey S, Hueber A: JAK-INHIBITION BY BARICITINIB AND TOFACITINIB AMELIORATES PATHOLOGICAL BONE LOSS Ann Rheum Dis. 2019;78(): A65-A65
Mössner R, Wilsmann-Theis D, Oji V, Gkogkolou P, Löhr S, Schulz P, Körber A, Christoph-Prinz J, Renner R, Schäkel K, Vogelsang L, Peters KP, Philipp S, Reich K, Ständer H, Jacobi A, Weyergraf A, Kingo K, Kõks S, Gerdes S, Steinz K, Schill T, Griewank KG, Müller M, Frey S, Ebertsch L, Uebe S, Sticherling M, Sticht H, Hüffmeier U: The genetic basis for most patients with pustular skin disease remains elusive. Br J Dermatol. 2018;178(3): 740-748
Kurow O, Frey B, Schuster L, Schmitt V, Adam S, Hahn M, Gilchrist D, McInnes IB, Wirtz S, Gaipl US, Krönke G, Schett G, Frey S, Hueber AJ: Full Length Interleukin 33 Aggravates Radiation-Induced Skin Reaction. Front Immunol. 2017;8(): 722
Frey S, Steigleder R, Distler J, Kratz O, Moll G, Golub Y: Molecular and epigenetic consequences of pre- and postnatal trauma in a mouse model Eur Neuropsychopharmacol. 2017;27(): S682-S682
Schmitt V, Hahn M, Kästele V, Wagner O, Wiendl M, Derer A, Taddeo A, Hahne S, Radbruch A, Jäck HM, Schuh W, Mielenz D, Gay S, Schett G, Hueber AJ, Frey S: Interleukin-36 receptor mediates the crosstalk between plasma cells and synovial fibroblasts. Eur J Immunol. 2017;47(12): 2101-2112
Hahn M, Frey S, Hueber AJ: The novel interleukin-1 cytokine family members in inflammatory diseases. Curr Opin Rheumatol. 2017;29(2): 208-213
Golub Y, Fabio C, Funke R, Frey S, Distler J, von Hörsten S, Freitag CM, Kratz O, Moll GH, Solati J: Effects of In utero environment and maternal behavior on neuroendocrine and behavioral alterations in a mouse model of prenatal trauma. Dev Neurobiol. 2016;76(11): 1254-1265
Wagner O, Kastele V, Schmitt V, Derer A, Engelkamp D, Gilchrist D, McInnes IB, Schett G, Frey S, Hueber AJ: INTERLEUKIN 33 SKIN OVEREXPRESSION DOES NOT INDUCE INFLAMMATION Ann Rheum Dis. 2014;73 1(): A78-A78
Derer A, Groetsch B, Harre U, Böhm C, Towne J, Schett G, Frey S, Hueber AJ: Blockade of IL-36 Receptor Signaling Does Not Prevent from TNF-Induced Arthritis. PLoS ONE. 2014;9(8): e101954
Kastele V, Wagner O, Derer A, Schmitt V, Schett G, Frey S, Hueber AJ: INTERLEUKIN-36 alpha ACTIVATES FIBROBLAST LIKE SYNOVIOCYTES Ann Rheum Dis. 2014;73 1(): A6-A7
Urbonaviciute V, Starke C, Pirschel W, Pohle S, Frey S, Daniel C, Amann K, Schett G, Herrmann M, Voll RE: Toll-like receptor 2 is required for autoantibody production and development of renal disease in pristane-induced lupus. Arthritis Rheum. 2013;65(6): 1612-23
Frey S, Derer A, Messbacher ME, Baeten DL, Bugatti S, Montecucco C, Schett G, Hueber AJ: The novel cytokine interleukin-36? is expressed in psoriatic and rheumatoid arthritis synovium. Ann Rheum Dis. 2013;72(9): 1569-74
Frey S, Derer A, Messbacher ME, Bugatti S, Baeten D, Montecucco C, Schett G, Hueber AJ: INTERLEUKIN-36 alpha IS EXPRESSED BY SYNOVIAL PLASMA CELLS AND INDUCES CYTOKINE PRODUCTION IN HUMAN FIBROBLASTS Ann Rheum Dis. 2013;72 1(): A78-A78
Lödermann B, Wunderlich R, Frey S, Schorn C, Stangl S, Rödel F, Keilholz L, Fietkau R, Gaipl US, Frey B: Low dose ionising radiation leads to a NF-?B dependent decreased secretion of active IL-1? by activated macrophages with a discontinuous dose-dependency. Int J Radiat Biol. 2012;88(10): 727-34
Starke C, Frey S, Wellmann U, Urbonaviciute V, Herrmann M, Amann K, Schett G, Winkler T, Voll RE: High frequency of autoantibody-secreting cells and long-lived plasma cells within inflamed kidneys of NZB/W F1 lupus mice. Eur J Immunol. 2011;41(7): 2107-12
Gückel E, Frey S, Zaiss MM, Schett G, Ghosh S, Voll RE: Cell-intrinsic NF-?B activation is critical for the development of natural regulatory T cells in mice. PLoS ONE. 2011;6(5): e20003

Dr. S. Frey

Medicine 3

Publications: Dr. rer. nat. S. Frey