Excellent. International. Curious.
The physicians and scientists of the Department of Medicine 3 investigate the molecular and cellular mechanisms of rheumatic diseases and autoimmune diseases. Our aim is to enhance the knowledge of pathogenesis of the disease in order to develop innovative diagnostic and therapies that reduce patients' suffering, improve their quality of life and open up long-term treatment options.
In our translational research, we investigate the complex processes that characterise inflammation and autoimmune diseases. Therefore, we analyse how immune cells interact, how inflammatory processes are controlled and how tissues and organs - including metabolic processes - communicate with each other. These findings form the basis for the development of innovative diagnostic methods and targeted therapy concepts.
The close integration of basic research and clinical application enables us to integrate our findings quickly and effectively into patient care. Our overarching goal is to sustainably improve the quality of life of people with rheumatic and autoimmune diseases and to open up long-term healing possibilities. With this holistic approach to translational research, we are continuously working to remove limitations and create new hope for patients.
Interdisciplinary Cell‑ and Tissue Immunology
Chronic Inflammation and Tissue Regeneration
We investigate processes in autoimmune and inflammatory diseases such as rheumatoid arthritis, psoriasis arthritis and systemic lupus erythematosus. We are deciphering why inflammation become chronic, why patient do not respond to certain drug and why drug relapses occurs. In addition, we analyze tissue regeneration during remission and tissue damage during relapse.
Research Groups
Prof. Dr. Aline Bozec
Prof. Dr. Ricardo Grieshaber-Bouyer
Dr. Bettina Grötsch
Prof. Dr. Dr. Martin Herrmann
PD Dr. Luis Munoz
Prof. Dr. Krystelle C. Nganou-Makamdop
Prof. Dr. Andreas Ramming
PD Dr. Ulrike Steffen
Prof. Dr. Stefan Uderhardt
Prof. Dr. Mario Zaiss
Molecular and cellular components
We decompose our tissue analyses by delineating individual cells such as T cells, B cells, plasma cells, macrophages, neutrophils or stromal cells as fibroblasts forming a communicative network within the maintenance of health but also during disease development.
Research Groups
AG Prof. Dr. Ricardo Grieshaber-Bouyer
AG Prof. Dr. Dr. Martin Herrmann
AG PD. Dr. Luis Munoz
AG Prof. Dr. Krystelle C. Nganou-Makamdop
AG Prof. Dr. Andreas Ramming
Tissue and Organ Interactions
We are targeting our investigation in different tissues - such as bones, joints , skin, lung and gut where the interorgan communication is essential. We have focus studies in the immunometabolism deregulation where, we investigate how the interplay of tissue interaction and metabolism contributes to the development, progression or healing of diseases.
Research Groups
Prof. Dr. Aline Bozec
Dr. Bettina Grötsch
Prof. Dr. Andreas Ramming
Dr. Carina Scherbel
Prof. Dr. Stefan Uderhardt
Prof. Dr. Mario Zaiss
Translational Immunology and System Medicine
Innovative Immune Therapies
Our aim is to develop new therapy methods that specifically modulate the immune system. These include modern approaches such as specialised cell therapies that can positively influence the course of the disease.
Research Groups
Dr. Christina Bergmann
Prof. Dr. Ricardo Grieshaber-Bouyer
Prof. Dr. Thomas Harrer
Prof. Dr. Andreas Ramming
Studienambulanz
Moderne Diagnostic
With the help of advanced, high-resolution imaging and tissue analysis, we are developing new methods to recognise diseases at an early stage and treat them in a targeted manner.
Research Groups
Prof. Dr. Stefan Uderhardt
Dr. Harriet Morf
PD. Dr. Milena Pachowsky
Prof. Dr. Andreas Ramming
