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HLA - Laboratory

Laboratory for Immunogenetics

Head: Prof. Dr. med. Bernd Spriewald

The Laboratory for Immunogenetics and Transplantation is run as a joint facility of the Department of Medicine 3 and Medicine 5. It has been accredited by the European Federation for Immunogenetics (EFI) since 1999.

One of the basic tasks of the laboratory is to provide immunogenetic organ donor diagnostics and immunological care for the Eurotransplantbereich of the Transplantationsverbund Nordbayern with the transplant centers Erlangen-Nürnberg, Würzburg and Regensburg for solid organ transplantation. These tasks are performed on behalf of the German Foundation for Organ Transplantation (DSO).

In the field of bone marrow and blood stem cell transplantation, immunogenetic and immunological diagnostics are performed for potential family stem cell donors and recipients for the KMT Centre of the Universitätsklinikum Erlangen at Department of Medicine 5 and the Clinic for Children and Adolescents. In addition to high-resolution HLA Class I and II typing, the laboratory offers chimerism determinations after allogeneic stem cell transplantation. As a cooperation laboratory of Aktion Knochenmarkspende Bayern (AKB), we participate in typing campaigns for the AKB donor center.

A further task of the laboratory is the HLA diagnostics in connection with disease associations such as M. Bechterew, Reumatoide Arthritis, Zölliakie etc..

All services of the laboratory are also offered for external senders. Outside regular working hours there is a 24-hour on-call service for organ donor diagnostics.

Requisitions and declaration of consent

Note on the Gene Diagnostics Act (GenDG)

 In the opinion of the Executive Board of the German Society for Immunogenetics (DGI), HLA investigations aimed at establishing compatibility do not fulfil the criteria of a diagnostic genetic examination according to § 3 GenDG and are therefore not subject to the provisions of this Act. A corresponding declaration of consent can, of course, also be sent for immunogenetic tests within the scope of the compatibility assessment.

Commentary on the GenDG

Note on postal shipping
As part of the University Hospital, our laboratory cannot provide packaging material or refund postage costs. When sending samples, the valid regulations for the transport of hazardous substances and objects must be observed.

Regulations for postal dispatch