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Prof. Dr. J. Distler

Publications: Prof. Dr. med. J. Distler

  • Distler JHW, O'Reilly S: Epigenetic profiling of twins identify repression of KLF4 as a novel pathomechanism in systemic sclerosis. Ann Rheum Dis. 2022;81(2): 151-152
  • Pu W, Zhang R, Ma Y, Liu Q, Jiang S, Liu J, Zhao Y, Tu W, Guo G, Zuo X, Wang Q, Chen Y, Wu W, Zhou X, Distler JHW, Reveille JD, Zou H, Jin L, Mayes MD, Wang J: Genetic Associations of Non-Major Histocompatibility Complex Susceptibility Loci with Systemic Sclerosis in a Han Chinese Population. J Invest Dermatol. 2022;142(7): 2039-2042.e7
  • Zhou X, Trinh-Minh T, Tran-Manh C, Gießl A, Bergmann C, Györfi AH, Schett G, Distler JHW: Impaired Mitochondrial Transcription Factor A Expression Promotes Mitochondrial Damage to Drive Fibroblast Activation and Fibrosis in Systemic Sclerosis. Arthritis Rheumatol. 2022;74(5): 871-881
  • Manfredi AA, Ramirez GA, Godino C, Capobianco A, Monno A, Franchini S, Tombetti E, Corradetti S, Distler JHW, Bianchi ME, Rovere-Querini P, Maugeri N: Platelet Phagocytosis via P-selectin Glycoprotein Ligand 1 and Accumulation of Microparticles in Systemic Sclerosis. Arthritis Rheumatol. 2022;74(2): 318-328
  • Kuwana M, Allanore Y, Denton CP, Distler JH, Steen V, Khanna D, Matucci-Cerinic M, Mayes MD, Volkmann ER, Miede C, Gahlemann M, Quaresma Lic M, Alves M, Distler O: Nintedanib in Patients With Systemic Sclerosis-Associated Interstitial Lung Disease: Subgroup Analyses by Autoantibody Status and Modified Rodnan Skin Thickness Score. Arthritis Rheumatol. 2022;74(3): 518-526
  • Hughes M, Heal C, Henes J, Balbir-Gurman A, Distler JHW, Airò P, Müller-Ladner U, Hunzelmann N, Kerzberg E, Rudnicka L, Truchetet ME, Stebbings S, Tanaka Y, Hoffman-Vold AM, Gabrielli A, Distler O, Matucci-Cerinic M, EUSTAR Collaborators: Digital pitting scars are associated with a severe disease course and death in systemic sclerosis: a study from the EUSTAR cohort. Rheumatology (Oxford). 2022;61(3): 1141-1147
  • Shi X, Chen Y, Liu Q, Mei X, Liu J, Tang Y, Luo R, Sun D, Ma Y, Wu W, Tu W, Zhao Y, Xu W, Ke Y, Jiang S, Huang Y, Zhang R, Wang L, Chen Y, Xia J, Pu W, Zhu H, Zuo X, Li Y, Xu J, Gao F, Wei D, Chen J, Yin W, Wang Q, Dai H, Yang L, Guo G, Cui J, Song N, Zou H, Zhao S, Distler JHW, Jin L, Wang J: LDLR dysfunction induces LDL accumulation and promotes pulmonary fibrosis. Clin Transl Med. 2022;12(1):
  • Györfi AH, Schett G, Distler JHW: Response to: 'Correspondence on 'Glucocorticoid-induced relapse of COVID-19 in a patient with sarcoidosis'' by Jeny et al. Ann Rheum Dis. 2021;80(6):
  • Matei AE, Distler JHW: Response to: 'In search for the ideal anatomical composition of vascularised human skin equivalents for systemic sclerosis translational research: should we recruit the telocytes?' by Manetti and Matucci-Cerinic. Ann Rheum Dis. 2021;80(9):
  • Wollin L, Trinh-Minh T, Zhang Y, Distler JHW: The effect of nintedanib versus mycophenolate mofetil in the Fra2 mouse model of systemic sclerosis-associated interstitial lung disease. Clin Exp Rheumatol. 2021;39 Suppl 131(4): 134-141
  • Gyoerfi AH, Matei AE, Fuchs M, Rigau AR, Hong X, Honglin Z, Luber M, Bergmann C, Dees C, Ludolph I, Horch R, Distler O, Schett G, Kunz M, Distler JHW: ENGRAILED 1 COORDINATES CYTOSKELETAL ORGANIZATION TO PROMOTE MYOFIBROBLAST DIFFERENTIATION AND FIBROTIC TISSUE REMODELING Ann Rheum Dis. 2021;80 Suppl 1(): 391-391
  • Knitza J, Mohn J, Bergmann C, Kampylafka E, Hagen M, Bohr D, Morf H, Araujo E, Englbrecht M, Simon D, Kleyer A, Meinderink T, Vorbrüggen W, von der Decken CB, Kleinert S, Ramming A, Distler JHW, Vuillerme N, Fricker A, Bartz-Bazzanella P, Schett G, Hueber AJ, Welcker M: Accuracy, patient-perceived usability, and acceptance of two symptom checkers (Ada and Rheport) in rheumatology: interim results from a randomized controlled crossover trial. Arthritis Res Ther. 2021;23(1):
  • Maher T, Bourdin A, Volkmann E, Vettori S, Distler JHW, Alves M, Stock C, Distler O, SENSCIS Investigators: DECLINE IN FORCED VITAL CAPACITY (FVC) IN SUBJECTS WITH SYSTEMIC SCLEROSIS-ASSOCIATED INTERSTITIAL LUNG DISEASE (SSC-ILD) IN THE SENSCIS TRIAL VERSUS HYPOTHETICAL REFERENCE SUBJECTS WITHOUT LUNG DISEASE Ann Rheum Dis. 2021;80 Suppl 1(): 671-672
  • Kuster S, Jordan S, Elhai MD, Held U, Steigmiller K, Bruni C, Iannone F, Vettori S, Siegert E, Rednic S, Codullo V, Airo P, Braun-Moscovici Y, Hunzelmann N, Salvador MJ, Riccieri V, Gheorghiu AM, Alegre Sancho JJA, Romanowska-Prochnicka K, Castellvi I, Koetter I, Truchetet ME, Lopez-Longo FJ, Novikov P, Giollo A, Shirai Y, Belloli L, Zanatta E, Hachulla E, Smith V, Denton C, Ionescu R, Schmeiser T, Distler JHW, Gabrielli A, Hoffmann-Vold AM, Kuwana M, Allanore Y, Distler O, EUSTAR: EFFECTIVENESS AND SAFETY OF TOCILIZUMAB IN PATIENTS WITH SYSTEMIC SCLEROSIS: A PROPENSITY SCORE CONTROL MATCHED OBSERVATIONAL STUDY OF THE EUSTAR COHORT Ann Rheum Dis. 2021;80 Suppl 1(): 685-686
  • Györfi AH, Matei AE, Fuchs M, Liang C, Rigau AR, Hong X, Zhu H, Luber M, Bergmann C, Dees C, Ludolph I, Horch RE, Distler O, Wang J, Bengsch B, Schett G, Kunz M, Distler JHW: Engrailed 1 coordinates cytoskeletal reorganization to induce myofibroblast differentiation. J Exp Med. 2021;218(9):
  • Ly TD, Kleine A, Plümers R, Fischer B, Schmidt V, Hendig D, Distler JHW, Kuhn J, Knabbe C, Faust I: Cytokine-mediated induction of human xylosyltransferase-I in systemic sclerosis skin fibroblasts. Biochem Biophys Res Commun. 2021;549(): 34-39
  • Soare A, Distler JHW: Untitled Reply Arthritis Rheumatol. 2021;73(1): 179-180
  • Höppner J, Bruni C, Distler O, Robson SC, Burmester GR, Siegert E, Distler JHW: Purinergic signaling in systemic sclerosis. Rheumatology (Oxford). 2021;():
  • Hesselstrand R, Distler JHW, Riemekasten G, Wuttge DM, Törngren M, Nyhlén HC, Andersson F, Eriksson H, Sparre B, Tuvesson H, Distler O: An open-label study to evaluate biomarkers and safety in systemic sclerosis patients treated with paquinimod. Arthritis Res Ther. 2021;23(1):
  • Zhang Y, Summa L, Heckmann B, Distler JHW: EFFECTS OF THE AUTOTAXIN INHIBITOR ZIRITAXESTAT ON SKIN AND LUNG FIBROSIS IN A MURINE GRAFT-VERSUS-HOST DISEASE MODEL OF SYSTEMIC SCLEROSIS Ann Rheum Dis. 2021;80 Suppl 1(): 148-149
  • Hirschmann S, Fischer S, Klenske E, Dechant K, Distler JHW, Treutlein C, Neurath MF, Atreya R: Case report of severe constrictive perimyocarditis and ischemic hepatitis in a Crohn's disease patient upon infliximab-induced lupus-like syndrome. Therap Adv Gastroenterol. 2021;14():
  • Rius Rigau A, Luber M, Distler JHW: Mouse Models of Skin Fibrosis. Methods Mol Biol. 2021;2299(): 371-383
  • Dees C, Chakraborty D, Distler JHW: Cellular and molecular mechanisms in fibrosis. Exp Dermatol. 2021;30(1): 121-131
  • Bruni C, Heidenreich S, Duenas A, Hoffmann-Vold AM, Gabrielli A, Allanore Y, Chatelus E, Distler JHW, Hachulla E, Hsu V, Hunzelmann N, Khanna D, Truchetet ME, Walker U, Alves M, Schoof N, Saketkoo LA, Distler O: PATIENT PREFERENCES, TRADE-OFFS AND ACCEPTABLE RISKS IN THE TREATMENT OF SYSTEMIC SCLEROSIS-ASSOCIATED INTERSTITIAL LUNG DISEASE: A STEP TOWARDS SHARED DECISION-MAKING Ann Rheum Dis. 2021;80 Suppl 1(): 681-682
  • Zehender A, Li YN, Lin NY, Stefanica A, Nüchel J, Chen CW, Hsu HH, Zhu H, Ding X, Huang J, Shen L, Györfi AH, Soare A, Rauber S, Bergmann C, Ramming A, Plomann M, Eckes B, Schett G, Distler JHW: TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy. Nat Commun. 2021;12(1):
  • Tomcik M, Trinh-Minh T, Manh CT, Storkanova H, Storkanova L, Senolt L, Klingelhofer J, Hussain RI, Hallen J, Distler JHW: ANTI-S100A4 MONOCLONAL ANTIBODY TREATMENT AMELIORATES SKIN FIBROSIS IN INFLAMMATORY AND NON-INFLAMMATORY PRE-CLINICAL MODELS OF SYSTEMIC SCLEROSIS Ann Rheum Dis. 2021;80 Suppl 1(): 150-150
  • Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, Ávalos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, Bánréti Á, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Barilà D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Belgareh-Touzé N, Bellarosa C, Belleudi F, Belló Pérez M, Bello-Morales R, Beltran JSO, Beltran S, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Berlioz-Torrent C, Bernard A, Berthoux L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Billes VA, Binart N, Bincoletto C, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgran R, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonam SR, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bosch J, Bose S, Botana LM, Botas J, Boulanger CM, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Boya P, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Braus GH, Bravo-Sagua R, Bravo-San Pedro JM, Brest P, Bringer MA, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Buchrieser C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Budini M, Bultynck G, Burada F, Burgoyne JR, Burón MI, Bustos V, Büttner S, Butturini E, Byrd A, Cabas I, Cabrera-Benitez S, Cadwell K, Cai J, Cai L, Cai Q, Cairó M, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Calvo AC, Calvo-Rubio Barrera M, Camara NO, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campbell-Valois FX, Campello S, Campesi I, Campos JC, Camuzard O, Cancino J, Candido de Almeida D, Canesi L, Caniggia I, Canonico B, Cantí C, Cao B, Caraglia M, Caramés B, Carchman EH, Cardenal-Muñoz E, Cardenas C, Cardenas L, Cardoso SM, Carew JS, Carle GF, Carleton G, Carloni S, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carosi JM, Carra S, Carrier A, Carrier L, Carroll B, Carter AB, Carvalho AN, Casanova M, Casas C, Casas J, Cassioli C, Castillo EF, Castillo K, Castillo-Lluva S, Castoldi F, Castori M, Castro AF, Castro-Caldas M, Castro-Hernandez J, Castro-Obregon S, Catz SD, Cavadas C, Cavaliere F, Cavallini G, Cavinato M, Cayuela ML, Cebollada Rica P, Cecarini V, Cecconi F, Cechowska-Pasko M, Cenci S, Ceperuelo-Mallafré V, Cerqueira JJ, Cerutti JM, Cervia D, Cetintas VB, Cetrullo S, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chakrabarti O, Chakraborty T, Chakraborty T, Chami M, Chamilos G, Chan DW, Chan EYW, Chan ED, Chan HYE, Chan HH, Chan H, Chan MTV, Chan YS, Chandra PK, Chang CP, Chang C, Chang HC, Chang K, Chao J, Chapman T, Charlet-Berguerand N, Chatterjee S, Chaube SK, Chaudhary A, Chauhan S, Chaum E, Checler F, Cheetham ME, Chen CS, Chen GC, Chen JF, Chen LL, Chen L, Chen L, Chen M, Chen MK, Chen N, Chen Q, Chen RH, Chen S, Chen W, Chen W, Chen XM, Chen XW, Chen X, Chen Y, Chen YG, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen ZS, Chen Z, Chen ZH, Chen ZJ, Chen Z, Cheng H, Cheng J, Cheng SY, Cheng W, Cheng X, Cheng XT, Cheng Y, Cheng Z, Chen Z, Cheong H, Cheong JK, Chernyak BV, Cherry S, Cheung CFR, Cheung CHA, Cheung KH, Chevet E, Chi RJ, Chiang AKS, Chiaradonna F, Chiarelli R, Chiariello M, Chica N, Chiocca S, Chiong M, Chiou SH, Chiramel AI, Chiurchiù V, Cho DH, Choe SK, Choi AMK, Choi ME, Choudhury KR, Chow NS, Chu CT, Chua JP, Chua JJE, Chung H, Chung KP, Chung S, Chung SH, Chung YL, Cianfanelli V, Ciechomska IA, Cifuentes M, Cinque L, Cirak S, Cirone M, Clague MJ, Clarke R, Clementi E, Coccia EM, Codogno P, Cohen E, Cohen MM, Colasanti T, Colasuonno F, Colbert RA, Colell A, Čolić M, Coll NS, Collins MO, Colombo MI, Colón-Ramos DA, Combaret L, Comincini S, Cominetti MR, Consiglio A, Conte A, Conti F, Contu VR, Cookson MR, Coombs KM, Coppens I, Corasaniti MT, Corkery DP, Cordes N, Cortese K, Costa MDC, Costantino S, Costelli P, Coto-Montes A, Crack PJ, Crespo JL, Criollo A, Crippa V, Cristofani R, Csizmadia T, Cuadrado A, Cui B, Cui J, Cui Y, Cui Y, Culetto E, Cumino AC, Cybulsky AV, Czaja MJ, Czuczwar SJ, D'Adamo S, D'Amelio M, D'Arcangelo D, D'Lugos AC, D'Orazi G, da Silva JA, Dafsari HS, Dagda RK, Dagdas Y, Daglia M, Dai X, Dai Y, Dai Y, Dal Col J, Dalhaimer P, Dalla Valle L, Dallenga T, Dalmasso G, Damme M, Dando I, Dantuma NP, Darling AL, Das H, Dasarathy S, Dasari SK, Dash S, Daumke O, Dauphinee AN, Davies JS, Dávila VA, Davis RJ, Davis T, Dayalan Naidu S, De Amicis F, De Bosscher K, De Felice F, De Franceschi L, De Leonibus C, de Mattos Barbosa MG, De Meyer GRY, De Milito A, De Nunzio C, De Palma C, De Santi M, De Virgilio C, De Zio D, Debnath J, DeBosch BJ, Decuypere JP, Deehan MA, Deflorian G, DeGregori J, Dehay B, Del Rio G, Delaney JR, Delbridge LMD, Delorme-Axford E, Delpino MV, Demarchi F, Dembitz V, Demers ND, Deng H, Deng Z, Dengjel J, Dent P, Denton D, DePamphilis ML, Der CJ, Deretic V, Descoteaux A, Devis L, Devkota S, Devuyst O, Dewson G, Dharmasivam M, Dhiman R, di Bernardo D, Di Cristina M, Di Domenico F, Di Fazio P, Di Fonzo A, Di Guardo G, Di Guglielmo GM, Di Leo L, Di Malta C, Di Nardo A, Di Rienzo M, Di Sano F, Diallinas G, Diao J, Diaz-Araya G, Díaz-Laviada I, Dickinson JM, Diederich M, Dieudé M, Dikic I, Ding S, Ding WX, Dini L, Dinić J, Dinic M, Dinkova-Kostova AT, Dionne MS, Distler JHW, Diwan A, Dixon IMC, Djavaheri-Mergny M, Dobrinski I, Dobrovinskaya O, Dobrowolski R, Dobson RCJ, Đokić J, Dokmeci Emre S, Donadelli M, Dong B, Dong X, Dong Z, Dorn Ii GW, Dotsch V, Dou H, Dou J, Dowaidar M, Dridi S, Drucker L, Du A, Du C, Du G, Du HN, Du LL, du Toit A, Duan SB, Duan X, Duarte SP, Dubrovska A, Dunlop EA, Dupont N, Durán RV, Dwarakanath BS, Dyshlovoy SA, Ebrahimi-Fakhari D, Eckhart L, Edelstein CL, Efferth T, Eftekharpour E, Eichinger L, Eid N, Eisenberg T, Eissa NT, Eissa S, Ejarque M, El Andaloussi A, El-Hage N, El-Naggar S, Eleuteri AM, El-Shafey ES, Elgendy M, Eliopoulos AG, Elizalde MM, Elks PM, Elsasser HP, Elsherbiny ES, Emerling BM, Emre NCT, Eng CH, Engedal N, Engelbrecht AM, Engelsen AST, Enserink JM, Escalante R, Esclatine A, Escobar-Henriques M, Eskelinen EL, Espert L, Eusebio MO, Fabrias G, Fabrizi C, Facchiano A, Facchiano F, Fadeel B, Fader C, Faesen AC, Fairlie WD, Falcó A, Falkenburger BH, Fan D, Fan J, Fan Y, Fang EF, Fang Y, Fang Y, Fanto M, Farfel-Becker T, Faure M, Fazeli G, Fedele AO, Feldman AM, Feng D, Feng J, Feng L, Feng Y, Feng Y, Feng W, Fenz Araujo T, Ferguson TA, Fernández ÁF, Fernandez-Checa JC, Fernández-Veledo S, Fernie AR, Ferrante AW, Ferraresi A, Ferrari MF, Ferreira JCB, Ferro-Novick S, Figueras A, Filadi R, Filigheddu N, Filippi-Chiela E, Filomeni G, Fimia GM, Fineschi V, Finetti F, Finkbeiner S, Fisher EA, Fisher PB, Flamigni F, Fliesler SJ, Flo TH, Florance I, Florey O, Florio T, Fodor E, Follo C, Fon EA, Forlino A, Fornai F, Fortini P, Fracassi A, Fraldi A, Franco B, Franco R, Franconi F, Frankel LB, Friedman SL, Fröhlich LF, Frühbeck G, Fuentes JM, Fujiki Y, Fujita N, Fujiwara Y, Fukuda M, Fulda S, Furic L, Furuya N, Fusco C, Gack MU, Gaffke L, Galadari S, Galasso A, Galindo MF, Gallolu Kankanamalage S, Galluzzi L, Galy V, Gammoh N, Gan B, Ganley IG, Gao F, Gao H, Gao M, Gao P, Gao SJ, Gao W, Gao X, Garcera A, Garcia MN, Garcia VE, García-Del Portillo F, Garcia-Escudero V, Garcia-Garcia A, Garcia-Macia M, García-Moreno D, Garcia-Ruiz C, García-Sanz P, Garg AD, Gargini R, Garofalo T, Garry RF, Gassen NC, Gatica D, Ge L, Ge W, Geiss-Friedlander R, Gelfi C, Genschik P, Gentle IE, Gerbino V, Gerhardt C, Germain K, Germain M, Gewirtz DA, Ghasemipour Afshar E, Ghavami S, Ghigo A, Ghosh M, Giamas G, Giampietri C, Giatromanolaki A, Gibson GE, Gibson SB, Ginet V, Giniger E, Giorgi C, Girao H, Girardin SE, Giridharan M, Giuliano S, Giulivi C, Giuriato S, Giustiniani J, Gluschko A, Goder V, Goginashvili A, Golab J, Goldstone DC, Golebiewska A, Gomes LR, Gomez R, Gómez-Sánchez R, Gomez-Puerto MC, Gomez-Sintes R, Gong Q, Goni FM, González-Gallego J, Gonzalez-Hernandez T, Gonzalez-Polo RA, Gonzalez-Reyes JA, González-Rodríguez P, Goping IS, Gorbatyuk MS, Gorbunov NV, Görgülü K, Gorojod RM, Gorski SM, Goruppi S, Gotor C, Gottlieb RA, Gozes I, Gozuacik D, Graef M, Gräler MH, Granatiero V, Grasso D, Gray JP, Green DR, Greenhough A, Gregory SL, Griffin EF, Grinstaff MW, Gros F, Grose C, Gross AS, Gruber F, Grumati P, Grune T, Gu X, Guan JL, Guardia CM, Guda K, Guerra F, Guerri C, Guha P, Guillén C, Gujar S, Gukovskaya A, Gukovsky I, Gunst J, Günther A, Guntur AR, Guo C, Guo C, Guo H, Guo LW, Guo M, Gupta P, Gupta SK, Gupta S, Gupta VB, Gupta V, Gustafsson AB, Gutterman DD, H B R, Haapasalo A, Haber JE, Hać A, Hadano S, Hafrén AJ, Haidar M, Hall BS, Halldén G, Hamacher-Brady A, Hamann A, Hamasaki M, Han W, Hansen M, Hanson PI, Hao Z, Harada M, Harhaji-Trajkovic L, Hariharan N, Haroon N, Harris J, Hasegawa T, Hasima Nagoor N, Haspel JA, Haucke V, Hawkins WD, Hay BA, Haynes CM, Hayrabedyan SB, Hays TS, He C, He Q, He RR, He YW, He YY, Heakal Y, Heberle AM, Hejtmancik JF, Helgason GV, Henkel V, Herb M, Hergovich A, Herman-Antosiewicz A, Hernández A, Hernandez C, Hernandez-Diaz S, Hernandez-Gea V, Herpin A, Herreros J, Hervás JH, Hesselson D, Hetz C, Heussler VT, Higuchi Y, Hilfiker S, Hill JA, Hlavacek WS, Ho EA, Ho IHT, Ho PW, Ho SL, Ho WY, Hobbs GA, Hochstrasser M, Hoet PHM, Hofius D, Hofman P, Höhn A, Holmberg CI, Hombrebueno JR, Yi-Ren Hong CH, Hooper LV, Hoppe T, Horos R, Hoshida Y, Hsin IL, Hsu HY, Hu B, Hu D, Hu LF, Hu MC, Hu R, Hu W, Hu YC, Hu ZW, Hua F, Hua J, Hua Y, Huan C, Huang C, Huang C, Huang C, Huang C, Huang H, Huang K, Huang MLH, Huang R, Huang S, Huang T, Huang X, Huang YJ, Huber TB, Hubert V, Hubner CA, Hughes SM, Hughes WE, Humbert M, Hummer G, Hurley JH, Hussain S, Hussain S, Hussey PJ, Hutabarat M, Hwang HY, Hwang S, Ieni A, Ikeda F, Imagawa Y, Imai Y, Imbriano C, Imoto M, Inman DM, Inoki K, Iovanna J, Iozzo RV, Ippolito G, Irazoqui JE, 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Wang CY, Wang C, Wang C, Wang C, Wang CY, Wang D, Wang F, Wang F, Wang F, Wang G, Wang H, Wang H, Wang H, Wang HG, Wang J, Wang J, Wang J, Wang J, Wang K, Wang L, Wang L, Wang MH, Wang M, Wang N, Wang P, Wang P, Wang P, Wang P, Wang QJ, Wang Q, Wang QK, Wang QA, Wang WT, Wang W, Wang X, Wang X, Wang Y, Wang Y, Wang Y, Wang YY, Wang Y, Wang Y, Wang Y, Wang Y, Wang Z, Wang Z, Wang Z, Warnes G, Warnsmann V, Watada H, Watanabe E, Watchon M, Wawrzyńska A, Weaver TE, Wegrzyn G, Wehman AM, Wei H, Wei L, Wei T, Wei Y, Weiergräber OH, Weihl CC, Weindl G, Weiskirchen R, Wells A, Wen RH, Wen X, Werner A, Weykopf B, Wheatley SP, Whitton JL, Whitworth AJ, Wiktorska K, Wildenberg ME, Wileman T, Wilkinson S, Willbold D, Williams B, Williams RSB, Williams RL, Williamson PR, Wilson RA, Winner B, Winsor NJ, Witkin SS, Wodrich H, Woehlbier U, Wollert T, Wong E, Wong JH, Wong RW, Wong VKW, Wong WW, Wu AG, Wu C, Wu J, Wu J, Wu KK, Wu M, Wu SY, Wu S, Wu SY, Wu S, Wu WKK, Wu X, Wu X, Wu YW, Wu Y, Xavier RJ, Xia H, Xia L, Xia Z, Xiang G, Xiang J, Xiang M, Xiang W, Xiao B, Xiao G, Xiao H, Xiao HT, Xiao J, Xiao L, Xiao S, Xiao Y, Xie B, Xie CM, Xie M, Xie Y, Xie Z, Xie Z, Xilouri M, Xu C, Xu E, Xu H, Xu J, Xu J, Xu L, Xu WW, Xu X, Xue Y, Yakhine-Diop SMS, Yamaguchi M, Yamaguchi O, Yamamoto A, Yamashina S, Yan S, Yan SJ, Yan Z, Yanagi Y, Yang C, Yang DS, Yang H, Yang HT, Yang H, Yang JM, Yang J, Yang J, Yang L, Yang L, Yang M, Yang PM, Yang Q, Yang S, Yang S, Yang SF, Yang W, Yang WY, Yang X, Yang X, Yang Y, Yang Y, Yao H, Yao S, Yao X, Yao YG, Yao YM, Yasui T, Yazdankhah M, Yen PM, Yi C, Yin XM, Yin Y, Yin Z, Yin Z, Ying M, Ying Z, Yip CK, Yiu SPT, Yoo YH, Yoshida K, Yoshii SR, Yoshimori T, Yousefi B, Yu B, Yu H, Yu J, Yu J, Yu L, Yu ML, Yu SW, Yu VC, Yu WH, Yu Z, Yu Z, Yuan J, Yuan LQ, Yuan S, Yuan SF, Yuan Y, Yuan Z, Yue J, Yue Z, Yun J, Yung RL, Zacks DN, Zaffagnini G, Zambelli VO, Zanella I, Zang QS, Zanivan S, Zappavigna S, Zaragoza P, Zarbalis KS, Zarebkohan A, Zarrouk A, Zeitlin SO, Zeng J, Zeng JD, Žerovnik E, Zhan L, Zhang B, Zhang DD, Zhang H, Zhang H, Zhang H, Zhang H, Zhang H, Zhang H, Zhang H, Zhang HL, Zhang J, Zhang J, Zhang JP, Zhang KYB, Zhang LW, Zhang L, Zhang L, Zhang L, Zhang L, Zhang M, Zhang P, Zhang S, Zhang W, Zhang X, Zhang XW, Zhang X, Zhang X, Zhang X, Zhang X, Zhang XD, Zhang Y, Zhang Y, Zhang Y, Zhang YD, Zhang Y, Zhang YY, Zhang Y, Zhang Z, Zhang Z, Zhang Z, Zhang Z, Zhang Z, Zhang Z, Zhao H, Zhao L, Zhao S, Zhao T, Zhao XF, Zhao Y, Zhao Y, Zhao Y, Zhao Y, Zheng G, Zheng K, Zheng L, Zheng S, Zheng XL, Zheng Y, Zheng ZG, Zhivotovsky B, Zhong Q, Zhou A, Zhou B, Zhou C, Zhou G, Zhou H, Zhou H, Zhou H, Zhou J, Zhou J, Zhou J, Zhou J, Zhou K, Zhou R, Zhou XJ, Zhou Y, Zhou Y, Zhou Y, Zhou ZY, Zhou Z, Zhu B, Zhu C, Zhu GQ, Zhu H, Zhu H, Zhu H, Zhu WG, Zhu Y, Zhu Y, Zhuang H, Zhuang X, Zientara-Rytter K, Zimmermann CM, Ziviani E, Zoladek T, Zong WX, Zorov DB, Zorzano A, Zou W, Zou Z, Zou Z, Zuryn S, Zwerschke W, Brand-Saberi B, Dong XC, Kenchappa CS, Li Z, Lin Y, Oshima S, Rong Y, Sluimer JC, Stallings CL, Tong CK: Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021;17(1): 1-382
  • Dobrota R, Jordan S, Juhl P, Maurer B, Wildi L, Bay-Jensen AC, Karsdal MA, Herrick AL, Distler JHW, Allanore Y, Hoffmann-Vold AM, Siebuhr AS, Distler O: Circulating collagen neo-epitopes and their role in the prediction of fibrosis in patients with systemic sclerosis: a multicentre cohort study Lancet Rheumatol.. 2021;3(3): E175-E184
  • Wollin L, Trinh-Minh T, Zhang Y, Distler JHW: The effect of nintedanib versus mycophenolate mofetil in the Fra2 mouse model of systemic sclerosis-associated interstitial lung disease Clin Exp Rheumatol. 2021;39 Suppl 131(4): S134-S141
  • Stojanović SD, Fuchs M, Liang C, Schmidt K, Xiao K, Just A, Pfanne A, Pich A, Warnecke G, Braubach P, Petzold C, Jonigk D, Distler JHW, Fiedler J, Thum T, Kunz M: Reconstruction of the miR-506-Quaking axis in Idiopathic Pulmonary Fibrosis using integrative multi-source bioinformatics. Sci Rep. 2021;11(1):
  • Bergmann C, Distler JHW, Treutlein C, Tascilar K, Mueller AT, Atzinger A, Matei AE, Knitza J, Gyorfi AH, Lueck A, Dees C, Soare A, Ramming A, Schonau V, Distler O, Prante O, Ritt P, Goetz I, Koehner M, Cordes M, Baeuerle T, Kuwert T, Schett G, Schmidkonz C: 68GA-FAPI-04 PET/CT STUDY EXTENSION FOR THE ASSESSMENT OF FIBROBLAST ACTIVATION AND RISK EVALUATION IN SYSTEMIC SCLEROSIS-RELATED INTERSTITIAL LUNG DISEASE Ann Rheum Dis. 2021;80 Suppl 1(): 165-166
  • Distler JHW, Bergmann C, Kuwert T, Schmidkonz C: Quantification of Ga-68-FAPI-04 in systemic sclerosis-associated interstitial lung disease Reply Lancet Rheumatol.. 2021;3(7): E475-E477
  • Chakraborty D, Šumová B, Mallano T, Chen CW, Distler A, Bergmann C, Ludolph I, Horch RE, Gelse K, Ramming A, Distler O, Schett G, Šenolt L, Distler JHW: Author Correction: Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis. Nat Commun. 2021;12(1):
  • Duffy L, Henderson J, Brown M, Pryzborski S, Fullard N, Summa L, Distler JHW, Stratton R, O'Reilly S: Bone Morphogenetic Protein Antagonist Gremlin-1 Increases Myofibroblast Transition in Dermal Fibroblasts: Implications for Systemic Sclerosis. Front Cell Dev Biol. 2021;9():
  • Štorkánová H, Štorkánová L, Navrátilová A, Bečvář V, Hulejová H, Oreská S, Heřmánková B, Špiritović M, Bečvář R, Pavelka K, Vencovský J, Distler JHW, Šenolt L, Tomčík M: Inhibition of Hsp90 Counteracts the Established Experimental Dermal Fibrosis Induced by Bleomycin. Biomedicines. 2021;9(6):
  • Storkanova H, Cerezo LA, Oreska S, Spiritovic M, Hermankova B, Komarc M, Pavelka K, Vencovsky J, Distler JHW, Senolt L, Becvar R, Tomcik M: S100A4 PLASMA LEVELS CORRELATE WITH DISEASE ACTIVITY, SKIN FIBROSIS AND INTERSTITIAL LUNG DISEASE IN SYSTEMIC SCLEROSIS PATIENTS Ann Rheum Dis. 2021;80 Suppl 1(): 1233-1233
  • Matei AE, Marketa K, Gyorfi AH, Boxberger E, Soteriou D, Papava M, Muth J, Krater M, Schett G, Guck J, Distler JHW: CIRCULATING MONOCYTES HAVE DISTINCT PHYSICAL PROPERTIES THAT CORRELATE WITH DISEASE ACTIVITY AND SEVERITY AND PREDICT PROGRESSION IN SYSTEMIC SCLEROSIS Ann Rheum Dis. 2021;80 Suppl 1(): 1238-1238
  • Štorkánová H, Oreská S, Špiritović M, Heřmánková B, Bubová K, Komarc M, Pavelka K, Vencovský J, Distler JHW, Šenolt L, Bečvář R, Tomčík M: Plasma Hsp90 levels in patients with systemic sclerosis and relation to lung and skin involvement: a cross-sectional and longitudinal study. Sci Rep. 2021;11(1):
  • Bergmann C, Hallenberger L, Chenguiti Fakhouri S, Merlevede B, Brandt A, Dees C, Zhu H, Zehender A, Zhou X, Schwab A, Chen CW, Györfi AH, Matei AE, Chakraborty D, Trinh-Minh T, Rauber S, Coras R, Bozec A, Kreuter A, Ziemer M, Schett G, Distler JHW: X-linked inhibitor of apoptosis protein (XIAP) inhibition in systemic sclerosis (SSc). Ann Rheum Dis. 2021;80(8): 1048-1056
  • Györfi AH, Kopp M, May M, Vetter M, Uder M, Kremer AE, Schett G, Harrer T, Distler JHW: Glucocorticoid-induced relapse of COVID-19 in a patient with sarcoidosis. Ann Rheum Dis. 2021;80(6):
  • Xu X, Li YN, Chen CW, Trinh-Minh T, Schett G, Distler JHW: INACTIVATION OF ALDEHYDE DEHYDROGENASE 3A2 INHIBITS FIBROBLAST ACTIVATION AND TISSUE FIBROSIS Ann Rheum Dis. 2021;80 Suppl 1(): 391-391
  • Zehender A, Li YN, Lin NY, Gyoerfi AH, Soare A, Bergmann C, Ramming A, Schett G, Distler JHW: INHIBITION OF AUTOPHAGY PREVENTS PROGRESSION OF FIBROSIS IN MURINE MODELS OF SYSTEMIC SCLEROSIS Ann Rheum Dis. 2021;80 Suppl 1(): 1075-1075
  • Ross RL, Corinaldesi C, Migneco G, Carr IM, Antanaviciute A, Wasson CW, Carriero A, Distler JHW, Holmes S, El-Sherbiny YM, McKimmie CS, Del Galdo F: Targeting human plasmacytoid dendritic cells through BDCA2 prevents skin inflammation and fibrosis in a novel xenotransplant mouse model of scleroderma. Ann Rheum Dis. 2021;80(7): 920-929
  • Zhang Y, Shen L, Dreissigacker K, Zhu H, Trinh-Minh T, Meng X, Tran-Manh C, Dees C, Matei AE, Chen CW, Ditschkowski M, Krauss S, Winkler J, Wolff D, Ziemer M, Beilhack A, Karrer S, Herr W, Mackensen A, Schett G, Spriewald BM, Distler JHW: Targeting of canonical WNT signaling ameliorates experimental sclerodermatous chronic graft-versus-host disease. Blood. 2021;137(17): 2403-2416
  • Chen CW, Li YN, Trinh-Minh T, Honglin Z, Matei AE, Ding X, Manh CT, Xu X, Liebel C, Liang R, Huang MC, Lin NY, Ramming A, Schett G, Distler JHW: DYNAMIC CHANGES IN O-GLCNACYLATION REGULATE OSTEOCLAST DIFFERENTIATION AND BONE LOSS IN ARTHRITIS Ann Rheum Dis. 2021;80 Suppl 1(): 121-122
  • Highland KB, Distler O, Kuwana M, Allanore Y, Assassi S, Azuma A, Bourdin A, Denton CP, Distler JHW, Hoffmann-Vold AM, Khanna D, Mayes MD, Raghu G, Vonk MC, Gahlemann M, Clerisme-Beaty E, Girard M, Stowasser S, Zoz D, Maher TM, SENSCIS trial investigators: Efficacy and safety of nintedanib in patients with systemic sclerosis-associated interstitial lung disease treated with mycophenolate: a subgroup analysis of the SENSCIS trial. Lancet Respir Med. 2021;9(1): 96-106
  • Stegemann A, Flis D, Ziolkowski W, Distler JHW, Steinbrink K, Böhm M: The α7 Nicotinic Acetylcholine Receptor: A Promising Target for the Treatment of Fibrotic Skin Disorders. J Invest Dermatol. 2020;140(12): 2371-2379
  • Distler O, Assassi S, Cottin V, Cutolo M, Danoff SK, Denton CP, Distler JHW, Hoffmann-Vold AM, Johnson SR, Müller Ladner U, Smith V, Volkmann ER, Maher TM: Predictors of progression in systemic sclerosis patients with interstitial lung disease. Eur Respir J. 2020;55(5):
  • Knitza J, Cavagna L, Schett G, Distler JHW: Comment on: 'Idiopathic inflammatory myopathies and antisynthetase syndrome: contribution of antisynthetase antibodies to improve current classification criteria' by Greco et al. Ann Rheum Dis. 2020;79(7):
  • Worrell JC, Leslie J, Smith GR, Zaki MYW, Paish HL, Knox A, James ML, Cartwright TN, O'Reilly S, Kania G, Distler O, Distler JHW, Herrick AL, Jeziorska M, Borthwick LA, Fisher AJ, Mann J, Mann DA, Oakley F: cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosis. Rheumatology (Oxford). 2020;59(12): 3939-3951
  • Bütikofer L, Varisco PA, Distler O, Kowal-Bielecka O, Allanore Y, Riemekasten G, Villiger PM, Adler S, EUSTAR collaborators , Avouac J, Walker UA, Guiducci S, Riemekasten G, Airò P, Hachulla E, Valentini G, Carreira PE, Cozzi F, Gurman AB, Braun-Moscovici Y, Damjanov N, Ananieva LP, Scorza R, Jimenez S, Busquets J, Li M, Müller-Ladner U, Maurer B, Tyndall A, Lapadula G, Iannone F, Becvar R, Sierakowsky S, Bielecka OK, Cutolo M, Sulli A, Cuomo G, Vettori S, Rednic S, Nicoara I, Vlachoyiannopoulos P, Montecucco C, Caporali R, Novak S, Czirják L, Varju C, Chizzolini C, Kucharz EJ, Kotulska A, Kopec-Medrek M, Widuchowska M, Rozman B, Mallia C, Coleiro B, Gabrielli A, Farge D, Hij A, Hesselstrand R, Scheja A, Wollheim F, Martinovic D, Govoni M, Monaco AL, Hunzelmann N, Pellerito R, Bambara LM, Caramaschi P, Black C, Denton C, Henes J, Santamaria VO, Heitmann S, Krasowska D, Seidel M, Oleszowsky M, Burkhardt H, Himsel A, Salvador MJ, Stamenkovic B, Stankovic A, Tikly M, Starovoytova MN, Engelhart M, Strauss G, Nielsen H, Damgaard K, Szücs G, Mendoza AZ, de la Puente Buijdos C, Sifuentes Giraldo WA, Midtvedt Ø, Garen T, Launay D, Valesini G, Riccieri V, Ionescu RM, Opris D, Groseanu L, Wigley FM, Mihai CM, Cornateanu RS, Ionitescu R, Gherghe AM, Gorga M, Dobrota R, Bojinca M, Schett G, Distler JHW, Meroni P, Zeni S, Mouthon L, De Keyser F, Smith V, Cantatore FP, Corrado A, Ullman S, Iversen L, Pozzi MR, Eyerich K, Hein R, Knott E, Szechinski J, Wiland P, Szmyrka-Kaczmarek M, Sokolik R, Morgiel E, Krummel-Lorenz B, Saar P, Aringer M, Günther C, Anic B, Baresic M, Mayer M, Radominski SC, de Souza Müller C, Azevedo VF, Agachi S, Groppa L, Chiaburu L, Russu E, Zenone T, Stebbings S, Highton J, Stamp L, Chapman P, Baron M, O'Donnell J, Solanki K, Doube A, Veale D, O'Rourke M, Loyo E, Rosato E, Pisarri S, Tanaseanu CM, Popescu M, Dumitrascu A, Tiglea I, Chirieac R, Ancuta C, Furst DE, Kafaja S, de la Peña Lefebvre PG, Rubio SR, Exposito MV, Sibilia J, Chatelus E, Gottenberg JE, Chifflot H, Litinsky I, Venalis A, Butrimiene I, Venalis P, Rugiene R, Karpec D, Kerzberg E, Montoya F, Cosentino V, Castellvi I: ACE inhibitors in SSc patients display a risk factor for scleroderma renal crisis-a EUSTAR analysis. Arthritis Res Ther. 2020;22(1):
  • Moinzadeh P, Kuhr K, Siegert E, Blank N, Sunderkoetter C, Henes J, Krusche M, Schmalzing M, Worm M, Schmeiser T, Günther C, Aberer E, Susok L, Riemekasten G, Kreuter A, Zeidler G, Juche A, Hadjiski D, Müller-Ladner U, Gaebelein-Wissing N, Distler JHW, Sárdy M, Krieg T, Hunzelmann N: Scleroderma Renal Crisis: Risk Factors for an Increasingly Rare Organ Complication. J Rheumatol. 2020;47(2): 241-248
  • Hoffmann-Vold AM, Maher TM, Philpot EE, Ashrafzadeh A, Barake R, Barsotti S, Bruni C, Carducci P, Carreira PE, Castellvi I, Del Galdo F, Distler JHW, Foeldvari I, Fraticelli P, George PM, Griffiths B, Guillen-Del-Castillo A, Hamid AM, Horvath R, Hughes M, Kreuter M, Moazedi-Fuerst F, Olas J, Paul S, Rotondo C, Rubio-Rivas M, Seferian A, Tomcik M, Uzunhan Y, Walker UA, Wiesik-Szewczyk E, Distler O: The identification and management of interstitial lung disease in systemic sclerosis: evidence-based European consensus statements Lancet Rheumatol.. 2020;2(2): E71-E83
  • Soare A, Gyoerfi HA, Matei AE, Dees C, Rauber S, Wohlfahrt T, Chen CW, Ludolph I, Horch RE, Baeuerle T, von Hoersten S, Mihai C, Distler O, Ramming A, Schett G, Distler JHW: Dipeptidylpeptidase 4 as a Marker of Activated Fibroblasts and a Potential Target for the Treatment of Fibrosis in Systemic Sclerosis Arthritis Rheumatol. 2020;72(1): 137-149
  • Ledein L, Léger B, Dees C, Beyer C, Distler A, Vettori S, Boukaiba R, Bidouard JP, Schaefer M, Pernerstorfer J, Ruetten H, Jagerschmidt A, Janiak P, Distler JHW, Distler O, Illiano S: Translational engagement of lysophosphatidic acid receptor 1 in skin fibrosis: from dermal fibroblasts of patients with scleroderma to tight skin 1 mouse. Br J Pharmacol. 2020;177(18): 4296-4309
  • Matteson E, Distler O, Distler JHW, Kuwana M, Pope J, Seibold J, James A, Schlenker-Herceg R, Rohr K, Flaherty K: Reduced Decline in Forced Vital Capacity in Patients with Progressive Fibrosing Autoimmune Disease-Related Interstitial Lung Diseases (ILDs) Treated with Nintedanib Arthritis Rheumatol. 2020;72 Suppl 10():
  • Wuyts WA, Azuma A, Distler JHW, Sondergaard K, Proudman S, Cottin V, Erhardt E, Quaresma M, Gahlemann M, Alves M, Maher TM: Effects of nintedanib in patients with SSc-ILD and preserved and highly impaired lung function Eur Respir J. 2020;56 Suppl 64():
  • Moinzadeh P, Kuhr K, Siegert E, Mueller-Ladner U, Riemekasten G, Günther C, Kötter I, Henes J, Blank N, Zeidler G, Pfeiffer C, Juche A, Jandova I, Ehrchen J, Schmalzing M, Susok L, Schmeiser T, Sunderkoetter C, Distler JHW, Worm M, Kreuter A, Krieg T, Hunzelmann N, Registry of the German Network for Systemic Scleroderma: Older age onset of systemic sclerosis - accelerated disease progression in all disease subsets. Rheumatology (Oxford). 2020;59(11): 3380-3389
  • Storkanova H, Storkanova L, Oreska S, Spiritovic M, Hermankova B, Becvar R, Pavelka K, Vencovsky J, Distler JHW, Senolt L, Tomcik M: Hsp90 Inhibition Effectively Prevents Progression of Dermal Fibrosis and Induces Regression of Established Bleomycin-Induced Dermal Fibrosis Arthritis Rheumatol. 2020;72 Suppl 10():
  • Dees C, Pötter S, Zhang Y, Bergmann C, Zhou X, Luber M, Wohlfahrt T, Karouzakis E, Ramming A, Gelse K, Yoshimura A, Jaenisch R, Distler O, Schett G, Distler JH: TGF-β-induced epigenetic deregulation of SOCS3 facilitates STAT3 signaling to promote fibrosis. J Clin Invest. 2020;130(5): 2347-2363
  • Zhang Y, Shen L, Zhu H, Dreissigacker K, Distler D, Zhou X, Györfi AH, Bergmann C, Meng X, Dees C, Trinh-Minh T, Ludolph I, Horch R, Ramming A, Schett G, Distler JHW: PGC-1α regulates autophagy to promote fibroblast activation and tissue fibrosis. Ann Rheum Dis. 2020;79(9): 1227-1233
  • Schmidkonz C, Rauber S, Atzinger A, Agarwal R, Götz TI, Soare A, Cordes M, Prante O, Bergmann C, Kleyer A, Ritt P, Maschauer S, Hennig P, Toms J, Köhner M, Manger B, Stone JH, Haberkorn U, Baeuerle T, Distler JHW, Agaimy A, Kuwert T, Schett G, Ramming A: Disentangling inflammatory from fibrotic disease activity by fibroblast activation protein imaging. Ann Rheum Dis. 2020;79(11): 1485-1491
  • Zhang Y, Zhu H, Layritz F, Luo H, Wohlfahrt T, Chen CW, Soare A, Bergmann C, Ramming A, Groeber F, Reuter C, Fornasini G, Soukhareva N, Schreiber B, Ramamurthy S, Amann K, Schett G, Distler JHW: Recombinant Adenosine Deaminase Ameliorates Inflammation, Vascular Disease, and Fibrosis in Preclinical Models of Systemic Sclerosis. Arthritis Rheumatol. 2020;72(8): 1385-1395
  • Pachera E, Assassi S, Salazar GA, Stellato M, Renoux F, Wunderlin A, Blyszczuk P, Lafyatis R, Kurreeman F, de Vries-Bouwstra J, Messemaker T, Feghali-Bostwick CA, Rogler G, van Haaften WT, Dijkstra G, Oakley F, Calcagni M, Schniering J, Maurer B, Distler JH, Kania G, Frank-Bertoncelj M, Distler O: Long noncoding RNA H19X is a key mediator of TGF-β-driven fibrosis. J Clin Invest. 2020;130(9): 4888-4905
  • Alexander T, Henes J, Distler JHW, Schmalzing M, Blank N, Kötter I, Hiepe F: [Autologous hematopoietic stem cell transplantation for systemic sclerosis : Position statement of the stem cell therapy working party of the German Society of Rheumatology]. Z Rheumatol. 2020;79(5): 429-436
  • Jaeger VK, Tikly M, Xu D, Siegert E, Hachulla E, Airò P, Valentini G, Matucci Cerinic M, Distler O, Cozzi F, Carreira P, Allanore Y, Müller-Ladner U, Ananieva LP, Balbir-Gurman A, Distler JHW, Czirják L, Li M, Henes J, Jimenez SA, Smith V, Damjanov N, Denton CP, DelGaldo F, Saketkoo LA, Walker UA, and EUSTAR co-authors: Racial differences in systemic sclerosis disease presentation: a European Scleroderma Trials and Research group study. Rheumatology (Oxford). 2020;59(7): 1684-1694
  • González-Serna D, Ochoa E, López-Isac E, Julià A, Degenhardt F, Ortego-Centeno N, Radstake TRDJ, Franke A, Marsal S, Mayes MD, Martín J, Márquez A, Scleroderma Genetic Consortium , Assassi S, Zhou X, Tan FK, Arnett FC, Reveille JD, Gorlova O, Chen WV, Ying J, Gregersen PK, Lee AT, Voskuyl AE, de Vries-Bouwstra J, Magro-Checa C, Broen J, Koeleman BPC, Simeón CP, Fonollosa V, Guillén A, Carreira P, Castellví I, González-Gay MA, Ríos R, Callejas-Rubio JL, Vargas-Hitos JA, García-Portales R, Camps MT, Fernández-Nebro A, González-Escribano MF, García-Hernández FJ, Castillo MJ, Aguirre MÁ, Gómez-Gracia I, Rodríguez-Rodríguez L, Fernández-Gutiérrez B, de la Peña PG, Vicente E, Andreu JL, Fernández de Castro M, López-Longo FJ, Martínez L, Espinosa G, Tolosa C, Pros A, Rodríguez-Carballeira M, Narváez FJ, Rubio-Rivas M, Ortiz-Santamaría V, Madroñero AB, Díaz B, Trapiella L, Sousa A, Egurbide MV, Fanlo-Mateo P, Sáez-Comet L, Díaz-González F, Hernández V, Beltrán E, Román-Ivorra JA, Grau E, Alegre-Sancho JJ, Blanco-García FJ, Oreiro N, Freire M, Balsa A, Ortiz AM, Hunzelmann N, Riemekasten G, Distler JHW, Witte T, Airó P, Beretta L, Santaniello A, Bellocchi C, Lunardi C, Moroncini G, Gabrielli A: A cross-disease meta-GWAS identifies four new susceptibility loci shared between systemic sclerosis and Crohn's disease. Sci Rep. 2020;10(1):
  • Renoux F, Stellato M, Haftmann C, Vogetseder A, Huang R, Subramaniam A, Becker MO, Blyszczuk P, Becher B, Distler JHW, Kania G, Boyman O, Distler O: The AP1 Transcription Factor Fosl2 Promotes Systemic Autoimmunity and Inflammation by Repressing Treg Development. Cell Rep. 2020;31(13):
  • Chakraborty D, Zhu H, Jüngel A, Summa L, Li YN, Matei AE, Zhou X, Huang J, Trinh-Minh T, Chen CW, Lafyatis R, Dees C, Bergmann C, Soare A, Luo H, Ramming A, Schett G, Distler O, Distler JHW: Fibroblast growth factor receptor 3 activates a network of profibrotic signaling pathways to promote fibrosis in systemic sclerosis. Sci Transl Med. 2020;12(563):
  • Liang RF, Kagwiria R, Zehender A, Dees C, Bergmann C, Ramming A, Krasowska D, Michalska-Jakubus M, Kreuter A, Kraner ME, Schett G, Distler JHW: Acyltransferase skinny hedgehog regulates TGF beta-dependent fibroblast activation in SSc Ann Rheum Dis. 2019;78(9): 1269-1273
  • Codullo V, Cova E, Pandolfi L, Breda S, Morosini M, Frangipane V, Malatesta M, Calderan L, Cagnone M, Pacini C, Cavagna L, Recalde H, Distler JHW, Giustra M, Prosperi D, Colombo M, Meloni F, Montecucco C: Imatinib-loaded gold nanoparticles inhibit proliferation of fibroblasts and macrophages from systemic sclerosis patients and ameliorate experimental bleomycin-induced lung fibrosis J Control Release. 2019;310(): 198-208
  • Matei AE, Chen CW, Kiesewetter L, Gyoerfi AH, Li YN, Thuong Trinh-Minh TM, Xu XH, Cuong Tran Manh CT, van Kuppevelt T, Hansmann J, Jungel A, Schett G, Groeber-Becker F, Distler JHW: Vascularised human skin equivalents as a novel in vitro model of skin fibrosis and platform for testing of antifibrotic drugs Ann Rheum Dis. 2019;78(12): 1686-1692
  • Kreuter M, Bonella F, Blank N, Siegert E, Henes J, Worm M, Sunderkoetter C, Schmalzing M, Kreuter A, Guenther C, Susok L, Zeidler G, Koetter I, Mueller-Ladner U, Krieg T, Juche A, Schmeiser T, Riemekasten G, Aberer E, Gaebelein-Wissing N, Distler JHW, Sardy M, Pfeiffer C, Kuhr K, Lorenz H, Moinzadeh P, Hunzelmann N: Predictors for the Development of Systemic Sclerosis Associated Interstitial Lung Disease (SSc-ILD) - Data from the German SSc-Network Am J Respir Crit Care Med. 2019;199():
  • Lopez-Isac E, Acosta-Herrera M, Kerick M, Assassi S, Satpathy AT, Granja J, Mumbach MR, Beretta L, Simeon CP, Carreira P, Ortego-Centeno N, Castellvi I, Bossini-Castillo L, David Carmona FD, Orozco G, Hunzelmann N, Distler JHW, Franke A, Lunardi C, Moroncini G, Gabrielli A, de Vries-Bouwstra J, Wijmenga C, Koeleman BPC, Nordin A, Padyukov L, Hoffmann-Vold AM, Lie B, Rios R, Callejas JL, Vargas-Hitos JA, Garcia-Portales R, Camps MT, Fernandez-Nebro A, Gonzalez-Escribano MF, Garcia-Hernandez FJ, Castillo MJ, Aguirre MA, Gomez-Gracia I, Fernandez-Gutierrez B, Rodriguez-Rodriguez L, Garcia de la Pena PG, Vicente E, Andreu JL, Fernandez de Castro MF, Lopez-Longo FJ, Martinez L, Fonollosa V, Guillen A, Espinosa G, Tolosa C, Pros A, Rodriguez-Carballeira M, Narvaez FJ, Rubio-Rivas M, Ortiz-Santamaria V, Madronero AB, Gonzalez-Gay MA, Diaz B, Trapiella L, Sousa A, Egurbide MV, Fanlo-Mateo P, Saez-Comet L, Diaz F, Hernandez V, Beltran E, Roman-Ivorra JA, Grau E, Alegre-Sancho JJ, Freire M, Blanco-Garcia FJ, Oreiro N, Witte T, Kreuter A, Riemekasten G, Airo P, Magro C, Voskuyl AE, Vonk MC, Hesselstrand R, Proudman S, Stevens W, Nikpour M, Zochling J, Sahhar J, Roddy J, Nash P, Tymms K, Rischmueller M, Lester S, Vyse T, Herrick AL, Worthington J, Denton CP, Allanore Y, Brown MA, Radstake TRDJ, Fonseca C, Chang HY, Mayes MD, Martin J, European Scleroderma Grp ASIG: GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways Nat Commun. 2019;10():
  • Kreuter M, Bonella F, Blank N, Siegert E, Henes J, Worm M, Sunderkoetter C, Schmalzing M, Kreuter A, Guenther C, Susok L, Zeidler G, Koetter I, Mueller-Ladner U, Krieg T, Juche A, Schmeiser T, Riemekasten G, Aberer E, Gaebelein-Wissing N, Distler JHW, Sardy M, Pfeiffer C, Kuhr K, Lorenz HM, Moinzadeh P, Hunzelmann N: Does anti-acid treatment influence disease progression in SSc-ILD ? data from the German SSc-network Eur Respir J. 2019;54():
  • Kozlova A, Pachera E, Maurer B, Juengel A, Distler JHW, Kania G, Distler O: Regulation of Fibroblast Apoptosis and Proliferation by MicroRNA-125b in Systemic Sclerosis Arthritis Rheumatol. 2019;71(12): 2068-2080
  • Kreuter M, Bonella F, Blank N, Siegert E, Henes J, Worm M, Sunderkoetter C, Schmalzing M, Kreuter A, Guenther C, Susok L, Zeidler G, Koetter I, Mueller-Ladner U, Krieg T, Juche A, Schmeiser T, Riemekasten G, Aberer E, Gaebelein-Wissing N, Distler JHW, Sardy M, Pfeiffer C, Kuhr K, Lorenz HM, Moinzadeh P, Hunzelmann N: Long term outcomes of immunomodulatory drugs in SSc-ILD - data from the German SSc-network Eur Respir J. 2019;54():
  • Fasano S, Riccardi A, Messiniti V, Caramaschi P, Rosato E, Maurer B, Smith V, Siegert E, De Langhe E, Riccieri V, Airo P, Mihai C, Avouac J, Zanatta E, Walker UA, Iannone F, De la Pena Lefebvre PGD, Distler JHW, Vacca A, Distler O, Kowal-Bielecka O, Allanore Y, Valentini G: Revised European Scleroderma Trials and Research Group Activity Index is the best predictor of short-term severity accrual Ann Rheum Dis. 2019;78(12): 1681-1685
  • Distler JHW, Gyoerfi AH, Ramanujam M, Whitfield ML, Koenigshoff M, Lafyatis R: Shared and distinct mechanisms of fibrosis Nat Rev Rheumatol. 2019;15(12): 705-730
  • Wohlfahrt T, Rauber S, Uebe S, Luber M, Soare A, Ekici A, Weber S, Matei AE, Chen CW, Maier C, Karouzakis E, Kiener HP, Pachera E, Dees C, Beyer C, Daniel C, Gelse K, Kremer AE, Naschberger E, Stürzl M, Butter F, Sticherling M, Finotto S, Kreuter A, Kaplan MH, Jüngel A, Gay S, Nutt SL, Boykin DW, Poon GMK, Distler O, Schett G, Distler JHW, Ramming A: PU.1 controls fibroblast polarization and tissue fibrosis. Nature. 2019;566(7744): 344-349
  • Wollin L, Distler JHW, Redente EF, Riches DWH, Stowasser S, Schlenker-Herceg R, Maher TM, Kolb M: Potential of nintedanib in treatment of progressive fibrosing interstitial lung diseases Eur Respir J. 2019;54(3):
  • Sobanski V, Giovannelli J, Allanore Y, Riemekasten G, Airó P, Vettori S, Cozzi F, Distler O, Matucci-Cerinic M, Denton C, Launay D, Hachulla E, EUSTAR collaborators , Cerinic MM, Guiducci S, Walker U, Lapadula G, Iannone F, Becvar R, Sierakowsky S, Cutolo M, Sulli A, Valentini G, Cuomo G, Vettori S, Riemekasten G, Siegert E, Rednic S, Nicoara I, Kahan A, Vlachoyiannopoulos P, Montecucco C, Caporali R, Carreira PE, Novak S, Czirják L, Varju C, Chizzolini C, Kucharz EJ, Kotulska A, Kopec-Medrek M, Widuchowska M, Cozzi F, Rozman B, Mallia C, Coleiro B, Gabrielli A, Farge D, Wu C, Marjanovic Z, Faivre H, Hij D, Dhamadi R, Airó P, Hesselstrand R, Wollheim F, Wuttge DM, Andréasson K, Martinovic D, Balbir-Gurman A, Braun-Moscovici Y, Trotta F, Monaco AL, Hunzelmann N, Pellerito R, Bambara LM, Caramaschi P, Black C, Denton C, Damjanov N, Henes J, Santamaria VO, Heitmann S, Krasowska D, Seidel M, Burkhardt H, Himsel A, Salvador MJ, Da Silva JAP, Stamenkovic B, Stankovic A, Tikly M, Ananieva LP, Denisov LN, Müller-Ladner U, Frerix M, Tarner I, Scorza R, Engelhart M, Strauss G, Nielsen H, Damgaard K, Mendoza AZ, de la Puente C, Sifuentes Giraldo WA, Midtvedt Ø, Reiseter S, Hachulla E, Launay D, Valesini G, Riccieri V, Ionescu RM, Opris D, Groseanu L, Cornateanu RS, Ionitescu R, Gherghe AM, Soare A, Gorga M, Bojinca M, Schett G, Distler JH, Beyer C, Meroni P, Ingegnoli F, Mouthon L, Keyser F, Smith V, Cantatore FP, Corrado A, Pozzi MR, Eyerich K, Hein R, Knott E, Wiland P, Szmyrka-Kaczmarek M, Sokolik R, Morgiel E, Madej M, Krummel-Lorenz B, Saar P, Aringer M, Günther C, Westhovens R, De Langhe E, Lenaerts J, Anic B, Baresic M, Mayer M, Radominski SC, de Souza Müller C, Azevedo VF, Agachi S, Groppa L, Chiaburu L, Russu E, Popa S, Zenone T, Stebbings S, Highton J, Stamp L, Chapman P, O'Donnell J, Solanki K, Doube A, Veale D, O'Rourke M, Loyo E, Li M, Rosato E, Amoroso A, Gigante A, Tanaseanu CM, Popescu M, Dumitrascu A, Tiglea I, Foti R, Chirieac R, Ancuta C, Villiger P, Adler S, de la Pena Lefebvre PG, Rubio SR, Exposito MV, Sibilia J, Chatelus E, Gottenberg JE, Chifflot H, Litinsky I, Venalis A, Butrimiene I, Venalis P, Rugiene R, Karpec D, Saketkoo LA, Lasky JA, Kerzberg E, Montoya F, Cosentino V, Limonta M, Brucato AL, Lupi E, Spertini F, Ribi C, Buss G, Pasquali JL, Martin T, Gorse A: Phenotypes Determined by Cluster Analysis and Their Survival in the Prospective European Scleroderma Trials and Research Cohort of Patients With Systemic Sclerosis. Arthritis Rheumatol. 2019;71(9): 1553-1570
  • Elhai M, Boubaya M, Distler O, Smith V, Matucci-Cerinic M, Alegre Sancho JJ, Truchetet ME, Braun-Moscovici Y, Iannone F, Novikov PI, Lescoat A, Siegert E, Castellví I, Airó P, Vettori S, De Langhe E, Hachulla E, Erler A, Ananieva L, Krusche M, López-Longo FJ, Distler JHW, Hunzelmann N, Hoffmann-Vold AM, Riccieri V, Hsu VM, Pozzi MR, Ancuta C, Rosato E, Mihai C, Kuwana M, Saketkoo LA, Chizzolini C, Hesselstrand R, Ullman S, Yavuz S, Rednic S, Caimmi C, Bloch-Queyrat C, Allanore Y, for EUSTAR network , Guiducci S, Walker UA, Kyburz D, Lapadula G, Maurer B, Jordan S, Dobrota R, Becvar R, Sierakowsky S, Bielecka OK, Sulli A, Cutolo M, Cuomo G, Nicoara I, Kahan A, Vlachoyiannopoulos PG, Montecucco CM, Caporali R, Stork J, Inanc M, Carreira PE, Novak S, Czirják L, Varju C, Kucharz EJ, Kotulska A, Kopec-Medrek M, Widuchowska M, Cozzi F, Rozman B, Mallia C, Coleiro B, Gabrielli A, Farge D, Wu C, Marjanovic Z, Faivre H, Hij D, Dhamadi R, Wollheim F, Scheja A, Wuttge DM, Andréasson K, Martinovic D, Balbir-Gurman A, Trotta F, Monaco AL, Pellerito R, Mauriziano O, Caramaschi P, Morovic-Vergles J, Black C, Denton C, Damjanov N, Henes J, Santamaria VO, Heitmann S, Krasowska Matthias D, Hasler P, Burkhardt H, Himsel A, Bajocchi G, Pereira Da Silva JA, Salvador MJ, Stamenkovic B, Stankovic A, Selmi CF, Santis M, Tikly M, Denisov LN, Müller-Ladner U, Frerix M, Tarner I, Scorza R, Puppo F, Engelhart M, Strauss G, Nielsen H, Damgaard K, Szucs G, Mendoza AZ, Puente C, Sifuentes Giraldo WA, Midtvedt Ø, Reiseter S, Garen T, Launay D, Valesini G, Ionescu RM, Groseanu L, Opris D, Cornateanu RS, Ionitescu R, Gherghe AM, Soare A, Gorga M, Bojinca M, Milicescu M, Sunderkötter C, Kuhn A, Sandorfi N, Schett G, Beyer C, Meroni P, Ingegnoli F, Mouthon L, Keyser F, Melsens K, Cantatore FP, Corrado A, Iversen L, Mühlen CAV, Bohn JM, Lonzetti LS, Eyerich K, Hein R, Knott E, Wiland P, Szmyrka-Kaczmarek M, Sokolik R, Morgiel E, Madej M, Houssiau FA, Krummel-Lorenz B, Saar P, Aringer M, Günther C, Westhovens R, Lenaerts J, Anic B, Baresic M, Mayer M, Üprus M, Otsa K, Granel B, Müller CS, Radominski SC, Azevedo VF, Jimenez S, Busquets J, Agachi S, Groppa L, Chiaburu L, Russu E, Popa S, Zenone T, Pileckyte M, Mathieu A, Vacca A, Sampaio-Barros PD, Yoshinari NH, Marangoni RG, Martin P, Fuocco L, Stebbings S, Highton J, Chapman P, O'Donnell J, Stamp L, Doube A, Solanki K, Veale D, O'Rourke M, Loyo E, Li M, Abdel Atty Mohamed WA, Amoroso A, Gigante A, Oksel F, Yargucu F, Tanaseanu CM, Popescu M, Dumitrascu A, Tiglea I, Foti R, Chirieac R, Fürst D, Villiger P, Adler S, Laar JV, Kayser C, Fathi N, Hassanien M, de la Pena Lefebvre PG, Rubio SR, Exposito MV, Chatelus E, Sibilia J, Gottenberg JE, Chifflot H, Litinsky I, Emery P, Buch M, Galdo FD, Venalis A, Butrimiene I, Venalis P, Rugiene R, Karpec D, Lasky JA, Cosentino V, Kerzberg E, Montoya F, Bianchi W, Carneiro S, Maretti GB, Bianchi DV, Limonta M, Brucato AL, Lupi E, Rosner I, Rozenbaum M, Slobodin G, Boulman N, Rimar D, Couto M, Kahl S, Chen F, McCloskey D, Malveaux H, Spertini F, Ribi C, Buss G, Martin T, Guffroy A, Poindron V, Chotchaeva F, Mukhin NA, Moiseev S, Herrick A: Outcomes of patients with systemic sclerosis treated with rituximab in contemporary practice: a prospective cohort study. Ann Rheum Dis. 2019;78(7): 979-987
  • Hsu VM, Denton CP, Domsic RT, Furst DE, Rischmueller M, Stanislav M, Steen VD, Distler JHW, Korish S, Cooper A, Choi S, Schafer PH, Horan G, Hough DR: Pomalidomide in Patients with Interstitial Lung Disease due to Systemic Sclerosis: A Phase II, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study. J Rheumatol. 2018;45(3): 405-410
  • Gyoerfi AH, Matei AE, Distler JHW: Targeting TGF-beta signaling for the treatment of fibrosis Matrix Biol. 2018;68-69(): 8-27
  • Gocht A, Distler JHW, Spriewald B, Ramsperger-Gleixner M, Weyand M, Ensminger SM, Heim C: Effects of different serotonin receptor subtype antagonists on the development of cardiac allograft vasculopathy in murine aortic allografts. Transpl Immunol. 2018;49(): 43-53
  • Distler JHW: [New molecular mechanisms in the pathophysiology of rheumatic diseases]. Z Rheumatol. 2018;77(9): 766-768
  • Gocht A, Spriewald B, Distler JHW, Ramsperger-Gleixner M, Ensminger SM, Weyand M, Heim C: Small Molecule Tyrosine Kinase Inhibitor Nintedanib Reduces Development of Cardiac Allograft Vasculopathy in Murine Aortic Allografts. Transplant Direct. 2018;4(7):
  • Kozlova A, Pachera E, Maurer B, Juengel A, Distler JH, Kania G, Distler O: MICRORNA-125B REGULATES APOPTOSIS IN SYSTEMIC SCLEROSIS Ann Rheum Dis. 2018;77(): 733-734
  • Wei J, Marangoni RG, Fang F, Wang W, Huang J, Distler JHW, Varga J: The non-neuronal cyclin-dependent kinase 5 is a fibrotic mediator potentially implicated in systemic sclerosis and a novel therapeutic target. Oncotarget. 2018;9(12): 10294-10306
  • Biermann MHC, Boeltz S, Pieterse E, Knopf J, Rech J, Bilyy R, van der Vlag J, Tincani A, Distler JHW, Kroenke G, Schett GA, Herrmann M, Munoz LE: Autoantibodies Recognizing Secondary NEcrotic Cells Promote Neutrophilic Phagocytosis and Identify Patients With Systemic Lupus Erythematosus Front Immunol. 2018;9():
  • Matei AE, Beyer C, Györfi AH, Soare A, Chen CW, Dees C, Bergmann C, Ramming A, Friebe A, Hofmann F, Distler O, Schett G, Distler JHW: Protein kinases G are essential downstream mediators of the antifibrotic effects of sGC stimulators. Ann Rheum Dis. 2018;77(3):
  • Lopez-Isac E, Acosta-Herrera M, Assassi S, Simeon CP, Carreira PE, Castellvi I, Ortego-Centeno N, Beretta L, Lunardi C, Gabrielli A, Moroncini G, Hunzelmann N, Witte T, Distler JH, Franke A, Voskuyl AE, de Vries-Bouwstra J, Wijmenga C, Hesselstrand R, Nordin A, Hoffmann-Vold AM, Herrick A, Worthington J, Denton CP, Brown MA, Allanore Y, Radstake TR, Fonseca C, Mayes MD, Martin J, Australian Scleroderma Interest French GENESYS Consortium Spanish Scleroderma Grp: NEW SYSTEMIC SCLEROSIS RISK LOCI IDENTIFIED THROUGH A META-GWAS STRATEGY Ann Rheum Dis. 2018;77(): 189-189
  • Soare A, Weber S, Maul L, Rauber S, Gheorghiu AM, Luber M, Houssni I, Kleyer A, von Pickardt G, Gado M, Simon D, Rech J, Schett G, Distler JHW, Ramming A: Cutting Edge: Homeostasis of Innate Lymphoid Cells Is Imbalanced in Psoriatic Arthritis. J Immunol. 2018;200(4): 1249-1254
  • Zhang Y, Pötter S, Chen CW, Liang R, Gelse K, Ludolph I, Horch RE, Distler O, Schett G, Distler JHW, Dees C: Poly(ADP-ribose) polymerase-1 regulates fibroblast activation in systemic sclerosis. Ann Rheum Dis. 2018;77(5): 744-751
  • Herrick AL, Peytrignet S, Lunt M, Pan X, Hesselstrand R, Mouthon L, Silman AJ, Dinsdale G, Brown E, Czirják L, Distler JHW, Distler O, Fligelstone K, Gregory WJ, Ochiel R, Vonk MC, Ancu?a C, Ong VH, Farge D, Hudson M, Matucci-Cerinic M, Balbir-Gurman A, Jobanputra P, Jordan AC, Stevens W, Moinzadeh P, Hall FC, Agard C, Anderson ME, Diot E, Madhok R, Akil M, Buch MH, Chung L, Damjanov NS, Gunawardena H, Lanyon P, Ahmad Y, Chakravarty K, MacGregor AJ, McHugh N, Müller-Ladner U, Riemekasten G, Becker M, Roddy J, Carreira PE, Fauchais AL, Hachulla E, Hamilton J, ?nanç M, McLaren JS, van Laar JM, Pathare S, Proudman SM, Rudin A, Sahhar J, Coppere B, Serratrice C, Sheeran T, Veale DJ, Grange C, Trad GS, Denton CP: Patterns and predictors of skin score change in early diffuse systemic sclerosis from the European Scleroderma Observational Study. Ann Rheum Dis. 2018;77(4): 563-570
  • Peytrignet S, Denton CP, Lunt M, Hesselstrand R, Mouthon L, Silman A, Pan X, Brown E, Czirják L, Distler JHW, Distler O, Fligelstone K, Gregory WJ, Ochiel R, Vonk M, Ancuta C, Ong VH, Farge D, Hudson M, Matucci-Cerinic M, Balbir-Gurman A, Jordan AC, Stevens W, Moinzadeh P, Hall FC, Agard C, Anderson ME, Diot E, Madhok R, Akil M, Buch MH, Chung L, Damjanov N, Gunawardena H, Lanyon P, Ahmad Y, Chakravarty K, MacGregor AJ, McHugh N, Müller-Ladner U, Riemekasten G, Becker M, Roddy J, Carreira PE, Fauchais AL, Hachulla E, Hamilton J, Inanc M, McLaren JS, van Laar JM, Pathare S, Proudman S, Rudin A, Sahhar J, Coppere B, Serratrice C, Sheeran T, Veale DJ, Grange C, Trad GS, Herrick AL: Disability, fatigue, pain and their associates in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study. Rheumatology (Oxford). 2018;57(2): 370-381
  • Jaeger VK, Siegert E, Hachulla E, Airo P, Valentini G, Matucci-Cerinic M, Scorza R, Distler O, Cozzi F, Carreira P, Allanore Y, Mueller-Ladner U, Ananieva LP, Balbir-Gurman A, Distler JHW, Czirjak L, n.a. MT, Henes J, Jimenez S, Smith V, Damjanov N, Denton C, delGaldo F, Tikly M, Saketkoo LA, Walker UA: Racial differences in SSc disease presentation: a European scleroderma trials and research group (EUSTAR) study Swiss Med Wkly. 2018;148(): 9S-9S
  • Kreuter M, Bonella F, Blank N, Siegert E, Henes J, Worm M, Sunderkoetter C, Schmalzing M, Kreuter A, Guenther C, Susok L, Zeidler G, Koetter I, Mueller-Ladner U, Krieg T, Juche A, Schmeiser T, Riemekasten G, Aberer E, Gaebelein-Wissing N, Distler JHW, Sardy M, Pfeiffer C, Kuhr K, Lorenz HM, Moinzadeh P, Hunzelmann N: Significance of pulmonary involvement in systemic sclerosis (SSc)- data from the German SSc-network Eur Respir J. 2018;52():
  • Horsburgh S, Todryk S, Ramming A, Distler JHW, O'Reilly S: Innate lymphoid cells and fibrotic regulation. Immunol Lett. 2018;195(): 38-44