PD Dr. A. Kleyer

Publications: PD Dr. med. A. Kleyer

Tascilar K, Fagni F, Kleyer A, Bayat S, Heidemann R, Steiger F, Krönke G, Bohr D, Ramming A, Hartmann F, Klett D, Federle A, Regensburger AP, Wagner AL, Knieling F, Neurath MF, Schett G, Waldner M, Simon D: Non-invasive metabolic profiling of inflammation in joints and entheses by multispectral optoacoustic tomography. Rheumatology (Oxford). 2023;62(2): 841-849
Fuchs F, Morf H, Mohn J, Mühlensiepen F, Ignatyev Y, Bohr D, Araujo E, Bergmann C, Simon D, Kleyer A, Vorbrüggen W, Ramming A, Distler JHW, Bartz-Bazzanella P, Schett G, Welcker M, Hueber AJ, Knitza J: Diagnostic delay stages and pre-diagnostic treatment in patients with suspected rheumatic diseases before special care consultation: results of a multicenter-based study. Rheumatol Int. 2023;43(3): 495-502
Labinsky H, Ukalovic D, Hartmann F, Runft V, Wichmann A, Jakubcik J, Gambel K, Otani K, Morf H, Taubmann J, Fagni F, Kleyer A, Simon D, Schett G, Reichert M, Knitza J: An AI-Powered Clinical Decision Support System to Predict Flares in Rheumatoid Arthritis: A Pilot Study. Diagnostics (Basel). 2023;13(1):
Vossen D, Knitza J, Klemm P, Haase I, Mucke J, Kernder A, Meyer M, Kleyer A, Sewerin P, Bendzuck G, Eis S, Krusche M, Morf H: [Acceptance of video consultation among patients with inflammatory rheumatic diseases depends on gender and location-Results of an online survey among patients and physicians]. Z Rheumatol. 2023;82(2): 108-113
Haschka J, Simon D, Bayat S, Messner Z, Kampylafka E, Fagni F, Skalicky S, Hackl M, Resch H, Zwerina J, Kleyer A, Cavallaro A, Sticherling M, Schett G, Kocijan R, Rech J: Identification of circulating microRNA patterns in patients in psoriasis and psoriatic arthritis. Rheumatology (Oxford). 2023;():
Sokolova MV, Hartmann F, Sieghart D, Bang H, Steiner G, Kleyer A, Schett G, Steffen U: Antibodies against citrullinated proteins of IgA isotype are associated with progression to rheumatoid arthritis in individuals at-risk. RMD Open. 2023;9(1):
Valor-Méndez L, Manger B, Knitza J, Schmidkonz C, Kleyer A, Schett G: Clinical Images: Tissue remodeling in autoimmune statin-induced necrotizing autoimmune myopathy. ACR Open Rheumatol. 2022;4(10): 835-836
Simon D, Tascilar K, Kleyer A, Bayat S, Kampylafka E, Sokolova M, Zekovic A, Hueber AJ, Rech J, Schuster L, Engel K, Sticherling M, Schett G: Association of Structural Entheseal Lesions With an Increased Risk of Progression From Psoriasis to Psoriatic Arthritis. Arthritis Rheumatol. 2022;74(2): 253-262
Valor-Méndez L, Wacker J, Schett G, Manger B, Fürst J, Strauß R, Kleyer A: Clinical Images: Voriconazole-induced synovitis, enthesitis, and periostitis. Arthritis Rheumatol. 2022;74(7):
Pachowsky ML, Morf H, Simon D, Schönau V, Valor-Mendez L, Knitza J, Fagni F, Engel K, Uder M, Hueber A, Schmidkonz C, Schett G, Kleyer A: Cinematic rendering in rheumatic diseases-Photorealistic depiction of pathologies improves disease understanding for patients. Front Med (Lausanne). 2022;9():
Knevel R, Knitza J, Hensvold A, Circiumaru A, Bruce T, Evans S, Maarseveen T, Maurits M, Beaart-van de Voorde L, Simon D, Kleyer A, Johannesson M, Schett G, Huizinga T, Svanteson S, Lindfors A, Klareskog L, Catrina A: Rheumatic?-A Digital Diagnostic Decision Support Tool for Individuals Suspecting Rheumatic Diseases: A Multicenter Pilot Validation Study. Front Med (Lausanne). 2022;9():
Knitza J, Muehlensiepen F, Ignatyev Y, Fuchs F, Mohn J, Simon D, Kleyer A, Fagni F, Boeltz S, Morf H, Bergmann C, Labinsky H, Vorbrüggen W, Ramming A, Distler JHW, Bartz-Bazzanella P, Vuillerme N, Schett G, Welcker M, Hueber AJ: Patient's Perception of Digital Symptom Assessment Technologies in Rheumatology: Results From a Multicentre Study. Front Public Health. 2022;10():
Wegener LC, Werner F, Kleyer A, Simon D, Uder M, Janka R, Trattnig S, Welsch GH, Pachowsky ML: Changes in T2 Relaxation Time Mapping of Intervertebral Discs Adjacent to Vertebrae after Kyphoplasty Correlate with the Physical Clinical Outcome of Patients. Diagnostics (Basel). 2022;12(3):
Simon D, Kleyer A, Bui CD, Hueber A, Bang H, Ramming A, Rech J, Schett G: Microstructural Bone Changes Are Associated With Broad-Spectrum Autoimmunity and Predict the Onset of Rheumatoid Arthritis. Arthritis Rheumatol. 2022;74(3): 418-426
Valor-Méndez L, Manger B, Wacker J, Kleyer A, Schett G: Lymph node and pulmonary tuberculosis during upadacitinib treatment in a psoriatic arthritis patient. Rheumatol Adv Pract. 2022;6(2):
Fagni F, Schmidt K, Bohr D, Valor-Méndez L, Hartmann F, Tascilar K, Manger K, Manger B, Kleyer A, Simon D, Schett G, Harrer T: Effects of casirivimab/imdevimab on systemic and mucosal immunity against SARS-CoV-2 in B-cell depleted patients with autoimmune rheumatic diseases refractory to vaccination. RMD Open. 2022;8(1):
Zarbl J, Eimer E, Gigg C, Bendzuck G, Korinth M, Elling-Audersch C, Kleyer A, Simon D, Boeltz S, Krusche M, Mucke J, Muehlensiepen F, Vuillerme N, Krönke G, Schett G, Knitza J: Remote self-collection of capillary blood using upper arm devices for autoantibody analysis in patients with immune-mediated inflammatory rheumatic diseases. RMD Open. 2022;8(2):
Simon D, Tascilar K, Fagni F, Schmidt K, Krönke G, Kleyer A, Ramming A, Schoenau V, Bohr D, Knitza J, Harrer T, Manger K, Manger B, Schett G: Efficacy and safety of SARS-CoV-2 revaccination in non-responders with immune-mediated inflammatory disease. Ann Rheum Dis. 2022;81(7): 1023-1027
Folle L, Bayat S, Kleyer A, Fagni F, Kapsner LA, Schlereth M, Meinderink T, Breininger K, Tacilar K, Krönke G, Uder M, Sticherling M, Bickelhaupt S, Schett G, Maier A, Roemer F, Simon D: Advanced neural networks for classification of MRI in psoriatic arthritis, seronegative, and seropositive rheumatoid arthritis. Rheumatology (Oxford). 2022;61(12): 4945-4951
Studenic P, Hensvold A, Kleyer A, van der Helm-van Mil A, Pratt AG, Sieghart D, Krönke G, Williams R, de Souza S, Karlfeldt S, Johannesson M, Krogh NS, Klareskog L, Catrina AI: Prospective Studies on the Risk of Rheumatoid Arthritis: The European Risk RA Registry. Front Med (Lausanne). 2022;9():
Folle L, Simon D, Tascilar K, Krönke G, Liphardt AM, Maier A, Schett G, Kleyer A: Deep Learning-Based Classification of Inflammatory Arthritis by Identification of Joint Shape Patterns-How Neural Networks Can Tell Us Where to "Deep Dive" Clinically. Front Med (Lausanne). 2022;9():
Mackensen A, Mueller F, Mougiakakos D, Boltz S, Wilhelm A, Aigner M, Volkl S, Simon D, Kleyer A, Munoz L, Kretschmann S, Kharboutli S, Gary R, Reimann H, Rosler W, Uderhardt S, Bang H, Herrmann M, Ekici AB, Buettner C, Habenicht KM, Winkler TH, Kronke G, Schett G: Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus (September, 10.1038/s41591-022-02017-5, 2022) Nat Med. 2022;():
Schmetzer C, Vogt E, Stellar L, Godonou ET, Liphardt AM, Muehlensiepen F, Vuillerme N, Hueber AJ, Kleyer A, Krönke G, Schett G, Simon D, Knitza J: Self-collection of capillary blood and saliva to determine COVID-19 vaccine immunogenicity in patients with immune-mediated inflammatory diseases and health professionals. Front Public Health. 2022;10():
Knitza J, Janousek L, Kluge F, von der Decken CB, Kleinert S, Vorbrüggen W, Kleyer A, Simon D, Hueber AJ, Muehlensiepen F, Vuillerme N, Schett G, Eskofier BM, Welcker M, Bartz-Bazzanella P: Machine learning-based improvement of an online rheumatology referral and triage system. Front Med (Lausanne). 2022;9():
Pachowsky ML, Raimondo MG, Xu C, Rauber S, Tascilar K, Labinsky H, Vogg M, Aziz Saad MS, Simon D, Rech J, Soare A, Braeuer L, Kleyer A, Schett G, Ramming A: Concise report: a minimal-invasive method to retrieve and identify entheseal tissue from psoriatic arthritis patients. Ann Rheum Dis. 2022;81(8): 1131-1135
Knitza J, Tascilar K, Vuillerme N, Eimer E, Matusewicz P, Corte G, Schuster L, Aubourg T, Bendzuck G, Korinth M, Elling-Audersch C, Kleyer A, Boeltz S, Hueber AJ, Krönke G, Schett G, Simon D: Accuracy and tolerability of self-sampling of capillary blood for analysis of inflammation and autoantibodies in rheumatoid arthritis patients-results from a randomized controlled trial. Arthritis Res Ther. 2022;24(1):
Simon D, Tascilar K, Kleyer A, Fagni F, Krönke G, Meder C, Dietrich P, Orlemann T, Kliem T, Mößner J, Liphardt AM, Schönau V, Bohr D, Schuster L, Hartmann F, Leppkes M, Ramming A, Pachowsky M, Schuch F, Ronneberger M, Kleinert S, Hueber AJ, Manger K, Manger B, Atreya R, Berking C, Sticherling M, Neurath MF, Schett G: Impact of Cytokine Inhibitor Therapy on the Prevalence, Seroconversion Rate, and Longevity of the Humoral Immune Response Against SARS-CoV-2 in an Unvaccinated Cohort. Arthritis Rheumatol. 2022;74(5): 783-790
Simon D, Tascilar K, Fagni F, Kleyer A, Krönke G, Meder C, Dietrich P, Orlemann T, Mößner J, Taubmann J, Mutlu MY, Knitza J, Kemenes S, Liphardt AM, Schönau V, Bohr D, Schuster L, Hartmann F, Minopoulou I, Leppkes M, Ramming A, Pachowsky M, Schuch F, Ronneberger M, Kleinert S, Hueber AJ, Manger K, Manger B, Atreya R, Berking C, Sticherling M, Neurath MF, Schett G: Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease: a prospective cohort study. Lancet Rheumatol.. 2022;4(9): e614-e625
Guckert M, Milanovic K, Hannig J, Simon D, Wettengl T, Evers D, Kleyer A, Keller T, Pitt J: The Disruption of Trust in the Digital Transformation Leading to Health 4.0. Front Digit Health. 2022;4():
Gräf M, Knitza J, Leipe J, Krusche M, Welcker M, Kuhn S, Mucke J, Hueber AJ, Hornig J, Klemm P, Kleinert S, Aries P, Vuillerme N, Simon D, Kleyer A, Schett G, Callhoff J: Comparison of physician and artificial intelligence-based symptom checker diagnostic accuracy. Rheumatol Int. 2022;42(12): 2167-2176
Valor-Méndez L, Dorn C, Manger B, Schett G, Kleyer A: Re-exposure with a TNF inhibitor bio-similar was well tolerated and led to sustained control of psoriatic arthritis after allergic reaction to the TNF inhibitor bio-originator. Rheumatol Adv Pract. 2022;6(3):
Simon D, Tascilar K, Schmidt K, Manger B, Weckwerth L, Sokolova M, Bucci L, Fagni F, Manger K, Schuch F, Ronneberger M, Hueber A, Steffen U, Mielenz D, Herrmann M, Harrer T, Kleyer A, Krönke G, Schett G: Humoral and Cellular Immune Responses to SARS-CoV-2 Infection and Vaccination in Autoimmune Disease Patients With B Cell Depletion. Arthritis Rheumatol. 2022;74(1): 33-37
Mackensen A, Müller F, Mougiakakos D, Böltz S, Wilhelm A, Aigner M, Völkl S, Simon D, Kleyer A, Munoz L, Kretschmann S, Kharboutli S, Gary R, Reimann H, Rösler W, Uderhardt S, Bang H, Herrmann M, Ekici AB, Buettner C, Habenicht KM, Winkler TH, Krönke G, Schett G: Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus. Nat Med. 2022;28(10): 2124-2132
Gasperi N, Schreiber N, Bosch P, Adinolfi A, Kleyer A, Hagen M, Gasperi C, Weger M, Kiechl S, Willeit J, Schett G, Iagnocco A, Gasperi A, Mayr A, Dejaco C: Ultrasound-detected inflammation is more common in clinically manifest hand osteoarthritis than in painless bony enlarged finger joints: subanalysis of the population-based Bruneck study. Ther Adv Musculoskelet Dis. 2022;14():
Bayat S, Tascilar K, Bohr D, Krönke G, Simon D, Knitza J, Hartmann F, Schett G, Kleyer A: Efficacy and drug persistence of baricitinib monotherapy is similar to combination therapy in patients with active RA: a prospective observational study. RMD Open. 2022;8(2):
Corte G, Bayat S, Tascilar K, Valor L, Schuster L, Knitza J, Schett G, Kleyer A, Simon D: ACCURACY AND PERFORMANCE OF A HANDHELD ULTRASOUND DEVICE TO ASSESS ARTICULAR AND PERIARTICULAR PATHOLOGIES IN PATIENTS WITH INFLAMMATORY ARTHRITIS Ann Rheum Dis. 2021;80 Suppl 1(): 979-980
Schenker HM, Tascilar K, Konerth L, Sergeeva M, Prade J, Strobelt S, Kleyer A, Simon D, Mendez L, Hagen M, Schönau V, Hueber A, Roesch J, Dörfler A, Hess A, Schett G, Rech J: Prediction of response to Certolizumab-Pegol in rheumatoid arthritis (PreCePRA) by functional MRI of the brain - Study protocol for a randomized double-blind controlled study. Contemp Clin Trials Commun. 2021;22():
Tascilar K, Simon D, Kroenke G, Kleyer A, Ramming A, Atreya R, Tenbusch M, Ueberla K, Berking C, Sticherling M, Neurath MF, Schett G: PATIENTS WITH IMMUNE MEDIATED INFLAMMATORY DISEASES ARE OVERREPRESENTED IN LOW-FREQUENCY VIRAL SYMPTOM CLUSTERS Ann Rheum Dis. 2021;80 Suppl 1(): 996-997
Simon D, Kleyer A, Bayat S, Knitza J, Valor-Mendez L, Schweiger M, Schett G, Tascilar K, Hueber AJ: Biomechanical stress in the context of competitive sports training triggers enthesitis. Arthritis Res Ther. 2021;23(1):
Valor-Méndez L, Sticherling M, Kleyer A, Schett G: Successful treatment of refractory palmoplantar psoriasis in a psoriatic arthritis patient with the JAK inhibitor tofacitinib. Clin Exp Rheumatol. 2021;39(1):
Simon D, Kleyer A, Bayat S, Knitza J, Valor L, Schweiger M, Schett G, Tascilar K, Hueber A: BIOMECHANICAL STRESS IN THE CONTEXT OF COMPETITIVE SPORTS TRAINING TRIGGERS ENTHESITIS Ann Rheum Dis. 2021;80 Suppl 1(): 1275-1275
Pfeil A, Franz M, Hoffmann T, Klemm P, Oelzner P, Müller-Ladner U, Hueber AJ, Lange U, Wolf G, Schett G, Simon D, Kleyer A: Virtual teaching for medical students during SARS-CoV-2 pandemic. Clin Exp Rheumatol. 2021;39(6): 1447-1448
Soellner ST, Welsch GH, Gelse K, Goldmann A, Kleyer A, Schett G, Pachowsky ML: gagCEST imaging at 3 T MRI in patients with articular cartilage lesions of the knee and intraoperative validation. Osteoarthritis Cartilage. 2021;29(8): 1163-1172
Valor-Méndez L, Manger B, Schett G, Kleyer A: [Severe Hepatitis E virus infection in a patient with rheumatoid arthritis treated with baricitinib]. Z Rheumatol. 2021;80(10): 980-983
Hagen M, Tascilar K, Reiser M, Valor L, Haschka J, Kleyer A, Hueber A, Manger B, Cobra J, Figuereido C, Finzel S, Tony HP, Wendler J, Kleinert S, Schuch F, Ronneberger M, Feuchtenberger M, Fleck M, Manger K, Ochs W, Schmitt-Haendle M, Lorenz HM, Alten R, Henes J, Krueger K, Rech J, Schett G: TREATMENT TAPERING AND WITHDRAWAL IN RHEUMATOID ARTHRITIS WITH STABLE REMISSION - FINAL ANALYSIS OF THE RETRO STUDY Ann Rheum Dis. 2021;80 Suppl 1(): 194-195
Folle L, Liu C, Simon D, Meinderink T, Liphardt AM, Kroenke G, Schett G, Maier A, Kleyer A: DIFFERENTIAL DIAGNOSIS OF RA AND PSA USING NEURAL NETWORKS ON THREE-DIMENSIONAL BONE SHAPE OF FINGER JOINTS Ann Rheum Dis. 2021;80 Suppl 1(): 86-87
Simon D, Tascilar K, Fagni F, Krönke G, Kleyer A, Meder C, Atreya R, Leppkes M, Kremer AE, Ramming A, Pachowsky ML, Schuch F, Ronneberger M, Kleinert S, Hueber AJ, Manger K, Manger B, Berking C, Sticherling M, Neurath MF, Schett G: SARS-CoV-2 vaccination responses in untreated, conventionally treated and anticytokine-treated patients with immune-mediated inflammatory diseases. Ann Rheum Dis. 2021;80(10): 1312-1316
Valor-Méndez L, Kleyer A, Rech J, Manger B, Schett G: Sustained clinical remission under infliximab/rituximab combination therapy in a patient with granulomatosis with polyangiitis. Auto Immun Highlights. 2021;12(1):
Tascilar K, Hagen M, Kleyer A, Simon D, Reiser M, Hueber AJ, Manger B, Englbrecht M, Finzel S, Tony HP, Schuch F, Kleinert S, Wendler J, Ronneberger M, Figueiredo CP, Cobra JF, Feuchtenberger M, Fleck M, Manger K, Ochs W, Schmitt-Haendle M, Lorenz HM, Nuesslein H, Alten R, Kruger K, Henes J, Schett G, Rech J: Treatment tapering and stopping in patients with rheumatoid arthritis in stable remission (RETRO): a multicentre, randomised, controlled, open-label, phase 3 trial Lancet Rheumatol.. 2021;3(11): E767-E777
Vodencarevic A, Tascilar K, Hartmann F, Reiser M, Hueber AJ, Haschka J, Bayat S, Meinderink T, Knitza J, Mendez L, Hagen M, Krönke G, Rech J, Manger B, Kleyer A, Zimmermann-Rittereiser M, Schett G, Simon D, RETRO study group: Advanced machine learning for predicting individual risk of flares in rheumatoid arthritis patients tapering biologic drugs. Arthritis Res Ther. 2021;23(1):
Klemm P, Kleyer A, Tascilar K, Schuster L, Meinderink T, Steiger F, Lange U, Mueller-Ladner U, Knitza J, Sewerin P, Mucke J, Pfeil A, Schett G, Hartmann F, Hueber A, Simon D: EVALUATION OF A VIRTUAL REALITY-BASED APPLICATION TO EDUCATE HEALTHCARE PROFESSIONALS AND MEDICAL STUDENTS ABOUT INFLAMMATORY ARTHRITIS Ann Rheum Dis. 2021;80 Suppl 1(): 1030-1031
Klemm P, Kleyer A, Tascilar K, Schuster L, Meinderink T, Steiger F, Lange U, Müller-Ladner U, Knitza J, Sewerin P, Mucke J, Pfeil A, Schett G, Hartmann F, Hueber AJ, Simon D: A Virtual Reality-Based App to Educate Health Care Professionals and Medical Students About Inflammatory Arthritis: Feasibility Study. JMIR Serious Games. 2021;9(2):
Kernder A, Morf H, Klemm P, Vossen D, Meyer M, Haase I, Mucke J, Kleyer A, Sewerin P, Bendzuck G, Eis S, Knitza J, Krusche M: DIGITAL RHEUMATOLOGY IN THE ERA OF COVID-19: RESULTS OF A NATIONAL PATIENT AND PHYSICIAN SURVEY Ann Rheum Dis. 2021;80 Suppl 1(): 1013-1014
Pachowsky M, Soellner S, Kleyer A, Welsch G, Schett G: CARTILAGE LESIONS OF THE KNEE: GAGCEST IMAGING AT 3 T MRI AND INTRAOPERATIVE VALIDATION Ann Rheum Dis. 2021;80 Suppl 1(): 60-61
Valor-Méndez L, Tascilar K, Simon D, Distler J, Kleyer A, Schett G, Rech J: Correspondence on 'Immunogenicity and safety of anti-SARS-CoV-2 mRNA vaccines in patients with chronic inflammatory conditions and immunosuppressive therapy in a monocentric cohort'. Ann Rheum Dis. 2021;80(10):
Kernder A, Morf H, Klemm P, Vossen D, Haase I, Mucke J, Meyer M, Kleyer A, Sewerin P, Bendzuck G, Eis S, Knitza J, Krusche M: Digital rheumatology in the era of COVID-19: results of a national patient and physician survey. RMD Open. 2021;7(1):
Lambrecht A, Vuillerme N, Raab C, Simon D, Messner EM, Hagen M, Bayat S, Kleyer A, Aubourg T, Schett G, Hueber A, Knitza J: Quality of a Supporting Mobile App for Rheumatic Patients: Patient-Based Assessment Using the User Version of the Mobile Application Scale (uMARS). Front Med (Lausanne). 2021;8():
Fagni F, Knitza J, Krusche M, Kleyer A, Tascilar K, Simon D: Digital Approaches for a Reliable Early Diagnosis of Psoriatic Arthritis. Front Med (Lausanne). 2021;8():
Valor-Méndez L, Kleyer A, Rech J, Manger B, Schett G: Long-term B-lymphocyte depletion and remission of granulomatosis with polyangiitis after two courses of rituximab treatment. Rheumatology (Oxford). 2021;60(5): e162-e164
Valor-Méndez L, Voskens C, Rech J, Kleyer A, Schett G: Herpes simplex infection in a patient with rheumatoid arthritis treated with baricitinib: a case report. Rheumatology (Oxford). 2021;60(4): e122-e123
Bleckwedel-Rolack L, Tascilar K, Nees V, Huehne J, Hueber A, Rech J, Schett G, Kleyer A, Liphardt AM: PATIENTS AT RISK FOR RA SHOW THE SAME AMOUNT OF ACUTE SOLUBLE CARTILAGE DEGRADATION MARKERS AFTER PHYSICAL ACTIVITY COMPARED TO PATIENTS WITH ESTABLISHED RA Ann Rheum Dis. 2021;80 Suppl 1(): 420-421
Andreev D, Liu M, Kachler K, Llerins Perez M, Kirchner P, Kölle J, Gießl A, Rauber S, Song R, Aust O, Grüneboom A, Kleyer A, Cañete JD, Ekici A, Ramming A, Finotto S, Schett G, Bozec A: Regulatory eosinophils induce the resolution of experimental arthritis and appear in remission state of human rheumatoid arthritis. Ann Rheum Dis. 2021;80(4): 451-468
Corte G, Bayat S, Tascilar K, Valor-Mendez L, Schuster L, Knitza J, Fagni F, Schett G, Kleyer A, Simon D: Performance of a Handheld Ultrasound Device to Assess Articular and Periarticular Pathologies in Patients with Inflammatory Arthritis. Diagnostics (Basel). 2021;11(7):
Phutane U, Liphardt AM, Bräunig J, Penner J, Klebl M, Tascilar K, Vossiek M, Kleyer A, Schett G, Leyendecker S: Evaluation of Optical and Radar Based Motion Capturing Technologies for Characterizing Hand Movement in Rheumatoid Arthritis-A Pilot Study. Sensors (Basel). 2021;21(4):
Zaharia OP, Pesta DH, Bobrov P, Kupriyanova Y, Herder C, Karusheva Y, Bódis K, Bönhof GJ, Knitza J, Simon D, Kleyer A, Hwang JH, Müssig K, Ziegler D, Burkart V, Schett G, Roden M, Szendroedi J: Reduced Muscle Strength Is Associated With Insulin Resistance in Type 2 Diabetes Patients With Osteoarthritis. J Clin Endocrinol Metab.. 2021;106(4): e1062-e1073
Knevel R, Knitza J, Hensvold A, Circiumaru A, Bruce T, Evans S, Maarseveen T, Maurits M, Beaart-van de Voorde L, Simon D, Kleyer A, Johannesson M, Schett G, Huizinga T, Svanteson S, Lindfors A, Klareskog L, Catrina A: RHEUMATIC? - A DIGITAL DIAGNOSTIC DECISION SUPPORT TOOL FOR INDIVIDUALS SUSPECTING RHEUMATIC DISEASES: A MULTICENTER VALIDATION STUDY Ann Rheum Dis. 2021;80 Suppl 1(): 87-88
Pfeil A, Marcus F, Hoffmann T, Klemm P, Oelzner P, Muller-Ladner U, Hueber A, Lange U, Wolf G, Schett G, Simon D, Kleyer A: EVALUATION OF A VIRTUAL REALITY TEACHING CONCEPT FOR MEDICAL STUDENTS DURING THE SARS-COV-2 PANDEMIC Ann Rheum Dis. 2021;80 Suppl 1(): 40-40
Friščić J, Böttcher M, Reinwald C, Bruns H, Wirth B, Popp SJ, Walker KI, Ackermann JA, Chen X, Turner J, Zhu H, Seyler L, Euler M, Kirchner P, Krüger R, Ekici AB, Major T, Aust O, Weidner D, Fischer A, Andes FT, Stanojevic Z, Trajkovic V, Herrmann M, Korb-Pap A, Wank I, Hess A, Winter J, Wixler V, Distler J, Steiner G, Kiener HP, Frey B, Kling L, Raza K, Frey S, Kleyer A, Bäuerle T, Hughes TR, Grüneboom A, Steffen U, Krönke G, Croft AP, Filer A, Köhl J, Klein K, Buckley CD, Schett G, Mougiakakos D, Hoffmann MH: The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts. Immunity. 2021;54(5): 1002-1021.e10
Kleyer A, Roemer F, Schett G, Manger B: Differenzialdiagnose Ruckenschmerzen mit Entzundungsparametern: Fallvorstellung: Manifestation einer CPPD als Crowned Dens Syndrom mit Befall peripherer Gelenke Aktuelle Rheumatol. 2021;46(01): 76-79
Valor-Méndez L, Kleyer A, Schett G, Manger B, Sticherling M: Contrary immediate effect of abatacept on skin and joint manifestations in psoriatic arthritis. Rheumatology (Oxford). 2021;60(9): e312-e313
Mucke J, Knitza J, Muehlensiepen F, Grahammer M, Stenzel R, Simon D, Kleyer A, Krönke G, Sharp C, Bendzuck G, Korinth M, Elling-Audersch C, Vuillerme N, Schett G, Pecher AC, Krusche M: TELERA-Asynchronous TELEmedicine for Patients With Rheumatoid Arthritis: Study Protocol for a Prospective, Multi-Center, Randomized Controlled Trial. Front Med (Lausanne). 2021;8():
Knitza J, Tascilar K, Gruber E, Kaletta H, Hagen M, Liphardt AM, Schenker H, Krusche M, Wacker J, Kleyer A, Simon D, Vuillerme N, Schett G, Hueber AJ: Accuracy and usability of a diagnostic decision support system in the diagnosis of three representative rheumatic diseases: a randomized controlled trial among medical students. Arthritis Res Ther. 2021;23(1):
Folle L, Meinderink T, Simon D, Liphardt AM, Krönke G, Schett G, Kleyer A, Maier A: Deep learning methods allow fully automated segmentation of metacarpal bones to quantify volumetric bone mineral density. Sci Rep. 2021;11(1):
Tascilar K, Simon D, Liphardt AM, Meinderink T, Bayat S, Rech J, Hueber A, Kroenke G, Schett G, Kleyer A: SPATIOTEMPORAL DYNAMICS OF BONE LOSS BEFORE AND AFTER THE ONSET OF RHEUMATOID ARTHRITIS Ann Rheum Dis. 2021;80 Suppl 1(): 88-89
Knitza J, Mohn J, Bergmann C, Kampylafka E, Hagen M, Bohr D, Morf H, Araujo E, Englbrecht M, Simon D, Kleyer A, Meinderink T, Vorbrüggen W, von der Decken CB, Kleinert S, Ramming A, Distler JHW, Vuillerme N, Fricker A, Bartz-Bazzanella P, Schett G, Hueber AJ, Welcker M: Accuracy, patient-perceived usability, and acceptance of two symptom checkers (Ada and Rheport) in rheumatology: interim results from a randomized controlled crossover trial. Arthritis Res Ther. 2021;23(1):
Simon D, Tascilar K, Kleyer A, Bayat S, Kampylafka E, Hueber A, Rech J, Schuster L, Engel K, Sticherling M, Schett G: Structural Entheseal Lesions in Psoriasis Patients Are Associated with an Increased Risk Ofprogression to Psoriatic Arthritis - A Prospective Cohort Study Arthritis Rheumatol. 2020;72 Suppl 10():
Rech J, Schenker H, Tascilar K, Hagen M, Kleyer A, Simon D, Mendez LV, Schoenau V, Prade J, Sergeeva M, Sulvakumar M, Strobelt S, Konerth L, Behrens F, Baerwald C, Finzel S, Voll R, Hueber A, Roesch J, Feist E, da Silva JAP, Doerfler A, Damjanov N, Hess A, Schett G: Brain fMRI Predicts Responses to Certolizumab Pegol in RA. an International, Multi-center, Randomized, Double-blind, Placebocontrolled Trial (PreCePRA) Arthritis Rheumatol. 2020;72 Suppl 10():
Ellmann H, Bayat S, Araujo E, Manger B, Kleyer A, Cavallaro A, Lell M, Schenker H, Simon D, Tascilar K, Baraf HSB, Schett G, Rech J: Effects of Conventional Uric Acid-Lowering Therapy on Monosodium Urate Crystal Deposits Arthritis Rheumatol. 2020;72(1): 150-156
Rech J, Tascilar K, Schenker H, Hagen M, Sergeeva M, Selvakumar M, Konerth L, Prade J, Strobelt S, Schonau V, Valor L, Hueber A, Simon D, Kleyer A, Behrens F, Baerwald C, Finzel S, Voll R, Feist E, Da Silva JAP, Doerfler A, Damjanov N, Hess A, Schett G: LONGITUDINAL CHANGE IN THE CENTRAL NERVOUS SYSTEM PAIN RESPONSE AFTER TREATMENT WITH CERTOLIZUMAB OR PLACEBO. A POST-HOC ANALYSIS FROM THE PRECEPRA TRIAL Ann Rheum Dis. 2020;79 Suppl 1(): 77-78
Knitza J, Mohn J, Bergmann C, Kampylafka E, Hagen M, Bohr D, Araujo E, Englbrecht M, Simon D, Kleyer A, Meinderink T, Vorbruggen W, Von der Decken CB, Kleinert S, Ramming A, Distler J, Bartz-Bazzanella P, Schett G, Hueber A, Welcker M: REAL-WORLD EFFECTIVENESS AND PERCEIVED USEFULNESS OF SYMPTOM CHECKERS IN RHEUMATOLOGY: INTERIM REPORT FROM THE PROSPECTIVE MULTICENTER BETTER STUDY Ann Rheum Dis. 2020;79 Suppl 1(): 1957-1957
Kampylafka E, Tascilar K, Lerchen V, Linz C, Sokolova M, Zekovic A, Kleyer A, Simon D, Rech J, Sticherling M, Schett G, Hueber A: Interleukin-17 Blockade Leads to Shifts from Stage-based Towards Response-based Disease Clusters- Comparative Data from Very Early and Established Psoriatic Arthritis Arthritis Rheumatol. 2020;72 Suppl 10():
Schenker H, Rech J, Tascilar K, Hagen M, Schoenau V, Sergeeva M, Selvakumar M, Konerth L, Prade J, Strobelt S, Valor L, Hueber A, Simon D, Kleyer A, Behrens F, Da Silva JAP, Baerwald C, Finzel S, Voll R, Feist E, Doerfler A, Damjanov N, Hess A, Schett G: CENTRAL NERVOUS SYSTEM PAIN RESPONSE AND COMPONENTS OF DISEASE ACTIVITY IN RA PATIENTS AFTER TREATMENT WITH CERTOLIZUMAB OR PLACEBO: A POST-HOC ANALYSIS FROM THE PRECEPRA TRIAL Ann Rheum Dis. 2020;79 Suppl 1(): 135-136
Rech J, Tascilar K, Schenker H, Sergeeva M, Selvakumar M, Konerth L, Prade J, Strobelt S, Hagen M, Schonau V, Valor L, Hueber A, Simon D, Kleyer A, Behrens F, Da Silva JAP, Baerwald C, Finzel S, Voll R, Feist E, Doerfler A, Damjanov N, Hess A, Schett G: PREDICTION OF RESPONSE TO CERTOLIZUMAB PEGOL TREATMENT BY FUNCTIONAL MRI OF THE BRAIN: AN INTERNATIONAL, MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL (PRECEPRA) Ann Rheum Dis. 2020;79 Suppl 1(): 952-952
Liphardt AM, Manger E, Liehr S, Bieniek L, Kleyer A, Simon D, Tascilar K, Sticherling M, Rech J, Schett G, Hueber A: Similar Impact of Psoriatic Arthritis and Rheumatoid Arthritis on Objective and Subjective Parameters of Hand Function Arthritis Rheumatol. 2020;72 Suppl 10():
Schmidkonz C, Rauber S, Atzinger A, Agarwal R, Götz TI, Soare A, Cordes M, Prante O, Bergmann C, Kleyer A, Ritt P, Maschauer S, Hennig P, Toms J, Köhner M, Manger B, Stone JH, Haberkorn U, Baeuerle T, Distler JHW, Agaimy A, Kuwert T, Schett G, Ramming A: Disentangling inflammatory from fibrotic disease activity by fibroblast activation protein imaging. Ann Rheum Dis. 2020;79(11): 1485-1491
Maarseveen TD, Meinderink T, Reinders MJT, Knitza J, Huizinga TWJ, Kleyer A, Simon D, van den Akker EB, Knevel R: Machine Learning Electronic Health Record Identification of Patients with Rheumatoid Arthritis: Algorithm Pipeline Development and Validation Study. JMIR Med Inform. 2020;8(11):
Treutlein C, Bäuerle T, Nagel AM, Guermazi A, Kleyer A, Simon D, Schett G, Hepp T, Uder M, Roemer FW: Comprehensive assessment of knee joint synovitis at 7 T MRI using contrast-enhanced and non-enhanced sequences. BMC Musculoskelet Disord. 2020;21(1):
Knitza J, Callhoff J, Chehab G, Hueber A, Kiltz U, Kleyer A, Krusche M, Simon D, Specker C, Schneider M, Voormann A, Welcker M, Richter JG: [Position paper of the commission on digital rheumatology of the German Society of Rheumatology: tasks, targets and perspectives for a modern rheumatology]. Z Rheumatol. 2020;79(6): 562-569
Bayat S, Tascilar K, Kleyer A, Simon D, Hueber A, Schett G: High Remission Rates in RA - Real Life Data from Bariticinib Arthritis Rheumatol. 2020;72 Suppl 10():
Simon D, Tascilar K, Krönke G, Kleyer A, Zaiss MM, Heppt F, Meder C, Atreya R, Klenske E, Dietrich P, Abdullah A, Kliem T, Corte G, Morf H, Leppkes M, Kremer AE, Ramming A, Pachowsky M, Schuch F, Ronneberger M, Kleinert S, Maier C, Hueber AJ, Manger K, Manger B, Berking C, Tenbusch M, Überla K, Sticherling M, Neurath MF, Schett G: Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion. Nat Commun. 2020;11(1):
Knitza J, Kleyer A, Klüppel M, Krauser M, Wacker J, Schett G, Simon D: [Online ultrasound learning modules in rheumatology : Innovative elective course increases student interest in the discipline of rheumatology]. Z Rheumatol. 2020;79(3): 276-279
Bayat S, Simon D, Schuster L, Schett G, Kleyer A: Cinematic Rendering Enables Depiction of Bone Anabolic Effects in Patients Treated with Baricitinib Arthritis Rheumatol. 2020;72 Suppl 10():
Valor-Méndez L, Hagen M, Kleyer A, Manger B, Schett G: Massive nodulous lesions on hands and feet in a RA patient and improvement under baricitinib treatment. RMD Open. 2020;6(3):
Bayat S, Tascilar K, Kaufmann V, Kleyer A, Simon D, Knitza J, Hartmann F, Adam S, Hueber A, Schett G: HIGH REMISSION RATES IN RA - REAL LIFE DATA FROM BARITICINIB Ann Rheum Dis. 2020;79 Suppl 1(): 1459-1460
Simon D, Haschka J, Muschitz C, Kocijan A, Baierl A, Kleyer A, Schett G, Kapiotis S, Resch H, Sticherling M, Rech J, Kocijan R: Bone microstructure and volumetric bone mineral density in patients with hyperuricemia with and without psoriasis. Osteoporos Int. 2020;31(5): 931-939
Pecherstorfer C, Simon D, Unbehend S, Ellmann H, Englbrecht M, Hartmann F, Figueiredo C, Hueber A, Haschka J, Kocijan R, Kleyer A, Schett G, Rech J, Bayat S: A Detailed Analysis of the Association between Urate Deposition and Erosions and Osteophytes in Gout. ACR Open Rheumatol. 2020;2(10): 565-572
Pachowsky ML, Kleyer A, Wagner L, Langenbach A, Simon D, Janka R, May M, Welsch GH: Quantitative T2 Mapping Shows Increased Degeneration in Adjacent Intervertebral Discs Following Kyphoplasty. Cartilage. 2020;11(2): 152-159
Kleyer A, Pachowsky M, Schuster L, Valor-Mendez L, Schett G, Hueber A, Simon D: Understanding Ankylosing Spondylitis - Arthritis Rheumatol. 2020;72 Suppl 10():
Adam S, Simon N, Steffen U, Andes FT, Scholtysek C, Müller DIH, Weidner D, Andreev D, Kleyer A, Culemann S, Hahn M, Schett G, Krönke G, Frey S, Hueber AJ: JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function. Sci Transl Med. 2020;12(530):
Simon D, Tascilar K, Unbehend S, Bayat S, Berlin A, Liphardt AM, Meinderink T, Rech J, Hueber AJ, Schett G, Kleyer A: Bone Mass, Bone Microstructure and Biomechanics in Patients with Hand Osteoarthritis. J Bone Miner Res. 2020;35(9): 1695-1702

PD Dr. A. Kleyer

Publications: PD Dr. med. A. Kleyer

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