Publications: PD Dr. med. A. Kleyer
- Humoral and Cellular Immune Responses to SARS-CoV-2 Infection and Vaccination in Autoimmune Disease Patients With B Cell Depletion. Arthritis Rheumatol. 2022;74(1): 33-37
- Impact of Cytokine Inhibitor Therapy on the Prevalence, Seroconversion Rate, and Longevity of the Humoral Immune Response Against SARS-CoV-2 in an Unvaccinated Cohort. Arthritis Rheumatol. 2022;74(5): 783-790
- Association of Structural Entheseal Lesions With an Increased Risk of Progression From Psoriasis to Psoriatic Arthritis. Arthritis Rheumatol. 2022;74(2): 253-262
- Microstructural Bone Changes Are Associated With Broad-Spectrum Autoimmunity and Predict the Onset of Rheumatoid Arthritis. Arthritis Rheumatol. 2022;74(3): 418-426
- Long-term B-lymphocyte depletion and remission of granulomatosis with polyangiitis after two courses of rituximab treatment. Rheumatology (Oxford). 2021;60(5): e162-e164
- TELERA-Asynchronous TELEmedicine for Patients With Rheumatoid Arthritis: Study Protocol for a Prospective, Multi-Center, Randomized Controlled Trial. Front Med (Lausanne). 2021;8():
- Herpes simplex infection in a patient with rheumatoid arthritis treated with baricitinib: a case report. Rheumatology (Oxford). 2021;60(4): e122-e123
- Contrary immediate effect of abatacept on skin and joint manifestations in psoriatic arthritis. Rheumatology (Oxford). 2021;60(9): e312-e313
- Accuracy, patient-perceived usability, and acceptance of two symptom checkers (Ada and Rheport) in rheumatology: interim results from a randomized controlled crossover trial. Arthritis Res Ther. 2021;23(1):
- Regulatory eosinophils induce the resolution of experimental arthritis and appear in remission state of human rheumatoid arthritis. Ann Rheum Dis. 2021;80(4): 451-468
- Accuracy and usability of a diagnostic decision support system in the diagnosis of three representative rheumatic diseases: a randomized controlled trial among medical students. Arthritis Res Ther. 2021;23(1):
- Deep learning methods allow fully automated segmentation of metacarpal bones to quantify volumetric bone mineral density. Sci Rep. 2021;11(1):
- SPATIOTEMPORAL DYNAMICS OF BONE LOSS BEFORE AND AFTER THE ONSET OF RHEUMATOID ARTHRITIS Ann Rheum Dis. 2021;80 Suppl 1(): 88-89
- Prediction of response to Certolizumab-Pegol in rheumatoid arthritis (PreCePRA) by functional MRI of the brain - Study protocol for a randomized double-blind controlled study. Contemp Clin Trials Commun. 2021;22():
- EVALUATION OF A VIRTUAL REALITY-BASED APPLICATION TO EDUCATE HEALTHCARE PROFESSIONALS AND MEDICAL STUDENTS ABOUT INFLAMMATORY ARTHRITIS Ann Rheum Dis. 2021;80 Suppl 1(): 1030-1031
- Reduced Muscle Strength Is Associated With Insulin Resistance in Type 2 Diabetes Patients With Osteoarthritis. J Clin Endocrinol Metab.. 2021;106(4): e1062-e1073
- ACCURACY AND PERFORMANCE OF A HANDHELD ULTRASOUND DEVICE TO ASSESS ARTICULAR AND PERIARTICULAR PATHOLOGIES IN PATIENTS WITH INFLAMMATORY ARTHRITIS Ann Rheum Dis. 2021;80 Suppl 1(): 979-980
- Virtual teaching for medical students during SARS-CoV-2 pandemic. Clin Exp Rheumatol. 2021;39(6): 1447-1448
- PATIENTS WITH IMMUNE MEDIATED INFLAMMATORY DISEASES ARE OVERREPRESENTED IN LOW-FREQUENCY VIRAL SYMPTOM CLUSTERS Ann Rheum Dis. 2021;80 Suppl 1(): 996-997
- Biomechanical stress in the context of competitive sports training triggers enthesitis. Arthritis Res Ther. 2021;23(1):
- BIOMECHANICAL STRESS IN THE CONTEXT OF COMPETITIVE SPORTS TRAINING TRIGGERS ENTHESITIS Ann Rheum Dis. 2021;80 Suppl 1(): 1275-1275
- gagCEST imaging at 3 T MRI in patients with articular cartilage lesions of the knee and intraoperative validation. Osteoarthritis Cartilage. 2021;29(8): 1163-1172
- [Severe Hepatitis E virus infection in a patient with rheumatoid arthritis treated with baricitinib]. Z Rheumatol. 2021;80(10): 980-983
- TREATMENT TAPERING AND WITHDRAWAL IN RHEUMATOID ARTHRITIS WITH STABLE REMISSION - FINAL ANALYSIS OF THE RETRO STUDY Ann Rheum Dis. 2021;80 Suppl 1(): 194-195
- Sustained clinical remission under infliximab/rituximab combination therapy in a patient with granulomatosis with polyangiitis. Auto Immun Highlights. 2021;12(1):
- DIFFERENTIAL DIAGNOSIS OF RA AND PSA USING NEURAL NETWORKS ON THREE-DIMENSIONAL BONE SHAPE OF FINGER JOINTS Ann Rheum Dis. 2021;80 Suppl 1(): 86-87
- SARS-CoV-2 vaccination responses in untreated, conventionally treated and anticytokine-treated patients with immune-mediated inflammatory diseases. Ann Rheum Dis. 2021;80(10): 1312-1316
- Treatment tapering and stopping in patients with rheumatoid arthritis in stable remission (RETRO): a multicentre, randomised, controlled, open-label, phase 3 trial Lancet Rheumatol.. 2021;3(11): E767-E777
- Advanced machine learning for predicting individual risk of flares in rheumatoid arthritis patients tapering biologic drugs. Arthritis Res Ther. 2021;23(1):
- Efficacy and safety of SARS-CoV-2 revaccination in non-responders with immune-mediated inflammatory disease. Ann Rheum Dis. 2021;():
- CARTILAGE LESIONS OF THE KNEE: GAGCEST IMAGING AT 3 T MRI AND INTRAOPERATIVE VALIDATION Ann Rheum Dis. 2021;80 Suppl 1(): 60-61
- A Virtual Reality-Based App to Educate Health Care Professionals and Medical Students About Inflammatory Arthritis: Feasibility Study. JMIR Serious Games. 2021;9(2):
- DIGITAL RHEUMATOLOGY IN THE ERA OF COVID-19: RESULTS OF A NATIONAL PATIENT AND PHYSICIAN SURVEY Ann Rheum Dis. 2021;80 Suppl 1(): 1013-1014
- [Acceptance of video consultation among patients with inflammatory rheumatic diseases depends on gender and location-Results of an online survey among patients and physicians]. Z Rheumatol. 2021;():
- Successful treatment of refractory palmoplantar psoriasis in a psoriatic arthritis patient with the JAK inhibitor tofacitinib. Clin Exp Rheumatol. 2021;39(1):
- EVALUATION OF A VIRTUAL REALITY TEACHING CONCEPT FOR MEDICAL STUDENTS DURING THE SARS-COV-2 PANDEMIC Ann Rheum Dis. 2021;80 Suppl 1(): 40-40
- Quality of a Supporting Mobile App for Rheumatic Patients: Patient-Based Assessment Using the User Version of the Mobile Application Scale (uMARS). Front Med (Lausanne). 2021;8():
- Digital Approaches for a Reliable Early Diagnosis of Psoriatic Arthritis. Front Med (Lausanne). 2021;8():
- Correspondence on 'Immunogenicity and safety of anti-SARS-CoV-2 mRNA vaccines in patients with chronic inflammatory conditions and immunosuppressive therapy in a monocentric cohort'. Ann Rheum Dis. 2021;80(10):
- Digital rheumatology in the era of COVID-19: results of a national patient and physician survey. RMD Open. 2021;7(1):
- Differenzialdiagnose Ruckenschmerzen mit Entzundungsparametern: Fallvorstellung: Manifestation einer CPPD als Crowned Dens Syndrom mit Befall peripherer Gelenke Aktuelle Rheumatol. 2021;46(01): 76-79
- PATIENTS AT RISK FOR RA SHOW THE SAME AMOUNT OF ACUTE SOLUBLE CARTILAGE DEGRADATION MARKERS AFTER PHYSICAL ACTIVITY COMPARED TO PATIENTS WITH ESTABLISHED RA Ann Rheum Dis. 2021;80 Suppl 1(): 420-421
- Evaluation of Optical and Radar Based Motion Capturing Technologies for Characterizing Hand Movement in Rheumatoid Arthritis-A Pilot Study. Sensors (Basel). 2021;21(4):
- Performance of a Handheld Ultrasound Device to Assess Articular and Periarticular Pathologies in Patients with Inflammatory Arthritis. Diagnostics (Basel). 2021;11(7):
- The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts. Immunity. 2021;54(5): 1002-1021.e10
- RHEUMATIC? - A DIGITAL DIAGNOSTIC DECISION SUPPORT TOOL FOR INDIVIDUALS SUSPECTING RHEUMATIC DISEASES: A MULTICENTER VALIDATION STUDY Ann Rheum Dis. 2021;80 Suppl 1(): 87-88
- HIGH REMISSION RATES IN RA - REAL LIFE DATA FROM BARITICINIB Ann Rheum Dis. 2020;79 Suppl 1(): 1459-1460
- Bone microstructure and volumetric bone mineral density in patients with hyperuricemia with and without psoriasis. Osteoporos Int. 2020;31(5): 931-939
- A Detailed Analysis of the Association between Urate Deposition and Erosions and Osteophytes in Gout. ACR Open Rheumatol. 2020;2(10): 565-572
- Understanding Ankylosing Spondylitis - Arthritis Rheumatol. 2020;72 Suppl 10():
- JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function. Sci Transl Med. 2020;12(530):
- Quantitative T2 Mapping Shows Increased Degeneration in Adjacent Intervertebral Discs Following Kyphoplasty. Cartilage. 2020;11(2): 152-159
- Bone Mass, Bone Microstructure and Biomechanics in Patients with Hand Osteoarthritis. J Bone Miner Res. 2020;35(9): 1695-1702
- Mobile Health Usage, Preferences, Barriers, and eHealth Literacy in Rheumatology: Patient Survey Study. JMIR Mhealth Uhealth. 2020;8(8):
- Quantification of hand muscle volume and composition in patients with rheumatoid arthritis, psoriatic arthritis and psoriasis. BMC Musculoskelet Disord. 2020;21(1):
- ELECTRONIC PATIENT-REPORTED OUTCOMES: A SURVEY ABOUT ACCEPTANCE, USAGE AND BARRIERS AMONG GERMAN RHEUMATOLOGISTS Ann Rheum Dis. 2020;79 Suppl 1(): 551-552
- T2 Mapping as a New Method for Quantitative Assessment of Cartilage Damage in Rheumatoid Arthritis. J Rheumatol. 2020;47(6): 820-825
- STRUCTURAL ENTHESEAL LESIONS IN PSORIASIS PATIENTS ARE ASSOCIATED WITH AN INCREASED RISK OF PROGRESSION TO PSORIATIC ARTHRITIS - A PROSPECTIVE COHORT STUDY Ann Rheum Dis. 2020;79 Suppl 1(): 33-34
- PREDICTION OF FLARES FOR RHEUMATOID ARTHRITIS PATIENTS ON BIOLOGIC DMARDS USING MACHINE LEARNING AND SUBSETS OF VARIABLES AVAILABLE TO PHYSICIANS, PATIENTS AND PAYERS Ann Rheum Dis. 2020;79 Suppl 1(): 955-956
- TYPE 3 INNATE LYMPHOID CELLS ARE KEY DRIVERS OF PSORIATIC ARTHRITIS Ann Rheum Dis. 2020;79 Suppl 1(): 1119-1120
- Acceptance, Usage, and Barriers of Electronic Patient-Reported Outcomes Among German Rheumatologists: Survey Study. JMIR mHealth uHealth. 2020;8(7): e18117
- Longitudinal Change in the Central Nervous System Pain Response After Treatment with Certolizumab or Placebo. a Post-hoc Analysis from the Pre-CEPRA Trial Arthritis Rheumatol. 2020;72 Suppl 10():
- IgA subclasses have different effector functions associated with distinct glycosylation profiles. Nat Commun. 2020;11(1):
- Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis. Nat Commun. 2020;11(1):
- FINE STRUCTURE ANALYSIS OF THE INTER-RELATION BETWEEN TOPHUS DEPOSITION AND BONE LESIONS IN GOUT USING A COMBINATION OF DUAL ENERGY AND HIGH-RESOLUTION CT Ann Rheum Dis. 2020;79 Suppl 1(): 1232-1232
- Secukinumab leads to shifts from stage-based towards response-based disease clusters-comparative data from very early and established psoriatic arthritis. Arthritis Res Ther. 2020;22(1):
- High Impact Sports Leads to Inflammatory Responses at Entheseal Sites Results of the BEAT Study (Badminton Enthesitis Arthrosonography Study) Arthritis Rheumatol. 2020;72 Suppl 10():
- Calcium pyrophosphate deposition disease induced inflammatory back pain. Rheumatology (Oxford). 2020;59(2): 456-456
- [Imaging of psoriatic arthritis and aspects of radiographic progression]. Z Rheumatol. 2020;79(1): 40-52
- Patients Receiving Cytokine Inhibitors Have Low Prevalence of SARS-CoV-2 Infection Arthritis Rheumatol. 2020;72 Suppl 10():
- Similar Impact of Psoriatic Arthritis and Rheumatoid Arthritis on Objective and Subjective Parameters of Hand Function. ACR Open Rheumatol. 2020;2(12): 734-740
- Machine Learning Electronic Health Record Identification of Patients with Rheumatoid Arthritis: Algorithm Pipeline Development and Validation Study. JMIR Med Inform. 2020;8(11):
- Structural Entheseal Lesions in Psoriasis Patients Are Associated with an Increased Risk Ofprogression to Psoriatic Arthritis - A Prospective Cohort Study Arthritis Rheumatol. 2020;72 Suppl 10():
- [Position paper of the commission on digital rheumatology of the German Society of Rheumatology: tasks, targets and perspectives for a modern rheumatology]. Z Rheumatol. 2020;79(6): 562-569
- Brain fMRI Predicts Responses to Certolizumab Pegol in RA. an International, Multi-center, Randomized, Double-blind, Placebocontrolled Trial (PreCePRA) Arthritis Rheumatol. 2020;72 Suppl 10():
- LONGITUDINAL CHANGE IN THE CENTRAL NERVOUS SYSTEM PAIN RESPONSE AFTER TREATMENT WITH CERTOLIZUMAB OR PLACEBO. A POST-HOC ANALYSIS FROM THE PRECEPRA TRIAL Ann Rheum Dis. 2020;79 Suppl 1(): 77-78
- Effects of Conventional Uric Acid-Lowering Therapy on Monosodium Urate Crystal Deposits Arthritis Rheumatol. 2020;72(1): 150-156
- CENTRAL NERVOUS SYSTEM PAIN RESPONSE AND COMPONENTS OF DISEASE ACTIVITY IN RA PATIENTS AFTER TREATMENT WITH CERTOLIZUMAB OR PLACEBO: A POST-HOC ANALYSIS FROM THE PRECEPRA TRIAL Ann Rheum Dis. 2020;79 Suppl 1(): 135-136
- REAL-WORLD EFFECTIVENESS AND PERCEIVED USEFULNESS OF SYMPTOM CHECKERS IN RHEUMATOLOGY: INTERIM REPORT FROM THE PROSPECTIVE MULTICENTER BETTER STUDY Ann Rheum Dis. 2020;79 Suppl 1(): 1957-1957
- Interleukin-17 Blockade Leads to Shifts from Stage-based Towards Response-based Disease Clusters- Comparative Data from Very Early and Established Psoriatic Arthritis Arthritis Rheumatol. 2020;72 Suppl 10():
- Disentangling inflammatory from fibrotic disease activity by fibroblast activation protein imaging. Ann Rheum Dis. 2020;79(11): 1485-1491
- PREDICTION OF RESPONSE TO CERTOLIZUMAB PEGOL TREATMENT BY FUNCTIONAL MRI OF THE BRAIN: AN INTERNATIONAL, MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL (PRECEPRA) Ann Rheum Dis. 2020;79 Suppl 1(): 952-952
- Similar Impact of Psoriatic Arthritis and Rheumatoid Arthritis on Objective and Subjective Parameters of Hand Function Arthritis Rheumatol. 2020;72 Suppl 10():
- Comprehensive assessment of knee joint synovitis at 7 T MRI using contrast-enhanced and non-enhanced sequences. BMC Musculoskelet Disord. 2020;21(1):
- High Remission Rates in RA - Real Life Data from Bariticinib Arthritis Rheumatol. 2020;72 Suppl 10():
- Massive nodulous lesions on hands and feet in a RA patient and improvement under baricitinib treatment. RMD Open. 2020;6(3):
- Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion. Nat Commun. 2020;11(1):
- [Online ultrasound learning modules in rheumatology : Innovative elective course increases student interest in the discipline of rheumatology]. Z Rheumatol. 2020;79(3): 276-279
- Cinematic Rendering Enables Depiction of Bone Anabolic Effects in Patients Treated with Baricitinib Arthritis Rheumatol. 2020;72 Suppl 10():
- Specialist training quo vadis? Z Rheumatol. 2019;78(8): 692-697
- Factors Associated with Persistent Drug-free Remission in Patients with Rheumatoid Arthritis Arthritis Rheumatol. 2019;71():
- FACTORS ASSOCIATED WITH PERSISTENT DRUG-FREE REMISSION IN PATIENTS WITH RHEUMATOID ARTHRITIS Ann Rheum Dis. 2019;78(): 730-730
- COMPARATIVE CHANGE IN QUALITY OF LIFE MEASURES IN PRECLINICAL AND ESTABLISHED PSORIATIC ARTHRITIS PATIENTSUNDER SECUKINUMAB TREATMENT. DATA DERIVED FROM THE PROSPECTIVE OPEN LABEL PSARTROS STUDY Ann Rheum Dis. 2019;78(): 1845-1845
- Cost-effective Tapering Algorithm in Patients with Rheumatoid Arthritis: Combination of Multibiomarker Disease Activity Score and Autoantibody Status. J Rheumatol. 2019;46(5): 460-466
- Interleukin 17 Blockade in Psoriasis Patients with Subclinical Joint Inflammation- Prospective Open Study to Influence the Course of the Disease by means of Secukinumab J Dtsch Dermatol Ges. 2019;17(): 127-128
- German Mobile Apps in Rheumatology: Review and Analysis Using the Mobile Application Rating Scale (MARS) JMIR mHealth uHealth. 2019;7(8):
- PHYSICAL FUNCTION IN RA PATIENTS IN REMISSION UNDERGOING TAPERING AND/OR STOPPING OF DMARDS Ann Rheum Dis. 2019;78(): 321-322
- Disease interception with interleukin-17 inhibition in high-risk psoriasis patients with subclinical joint inflammation-data from the prospective IVEPSA study. Arthritis Res Ther. 2019;21(1):
- Effect of disease-modifying anti-rheumatic drugs on bone structure and strength in psoriatic arthritis patients Arthritis Res Ther. 2019;21():
- SIZE MATTERS - EXTENT OF MONOSODIUM URATE DEPOSITS BUT NOT SERUM URATE LEVEL PREDICTS COMPLETE RESOLUTION OF MONOSODIUM URATE CRYSTAL DEPOSITS IN PATIENTS WITH GOUT Ann Rheum Dis. 2019;78(): 1295-1296