Medizin 3

Publications: PD Dr. med. A. Kleyer

Valor-Méndez L, Voskens C, Rech J, Kleyer A, Schett G: Herpes simplex infection in a patient with rheumatoid arthritis treated with baricitinib: a case report. Rheumatology (Oxford). 2021;60(4): e122-e123
Zaharia OP, Pesta DH, Bobrov P, Kupriyanova Y, Herder C, Karusheva Y, Bódis K, Bönhof GJ, Knitza J, Simon D, Kleyer A, Hwang JH, Müssig K, Ziegler D, Burkart V, Schett G, Roden M, Szendroedi J: Reduced Muscle Strength Is Associated With Insulin Resistance in Type 2 Diabetes Patients With Osteoarthritis. J Clin Endocrinol Metab.. 2021;106(4): e1062-e1073
Vodencarevic A, Tascilar K, Hartmann F, Reiser M, Hueber AJ, Haschka J, Bayat S, Meinderink T, Knitza J, Mendez L, Hagen M, Krönke G, Rech J, Manger B, Kleyer A, Zimmermann-Rittereiser M, Schett G, Simon D, RETRO study group: Advanced machine learning for predicting individual risk of flares in rheumatoid arthritis patients tapering biologic drugs. Arthritis Res Ther. 2021;23(1):
Valor-Méndez L, Sticherling M, Kleyer A, Schett G: Successful treatment of refractory palmoplantar psoriasis in a psoriatic arthritis patient with the JAK inhibitor tofacitinib. Clin Exp Rheumatol. 2021;39(1):
Knitza J, Kleyer A, Klüppel M, Krauser M, Wacker J, Schett G, Simon D: [Online ultrasound learning modules in rheumatology : Innovative elective course increases student interest in the discipline of rheumatology]. Z Rheumatol. 2020;79(3): 276-279
Valor-Méndez L, Kleyer A, Rech J, Manger B, Schett G: Long-term B-lymphocyte depletion and remission of granulomatosis with polyangiitis after two courses of rituximab treatment. Rheumatology (Oxford). 2020;():
Simon D, Tascilar K, Krönke G, Kleyer A, Zaiss MM, Heppt F, Meder C, Atreya R, Klenske E, Dietrich P, Abdullah A, Kliem T, Corte G, Morf H, Leppkes M, Kremer AE, Ramming A, Pachowsky M, Schuch F, Ronneberger M, Kleinert S, Maier C, Hueber AJ, Manger K, Manger B, Berking C, Tenbusch M, Überla K, Sticherling M, Neurath MF, Schett G: Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion. Nat Commun. 2020;11(1):
Steffen U, Koeleman CA, Sokolova MV, Bang H, Kleyer A, Rech J, Unterweger H, Schicht M, Garreis F, Hahn J, Andes FT, Hartmann F, Hahn M, Mahajan A, Paulsen F, Hoffmann M, Lochnit G, Munoz LE, Wuhrer M, Falck D, Herrmann M, Schett G: IgA subclasses have different effector functions associated with distinct glycosylation profiles. Nat Commun. 2020;11(1):
Bayat S, Tascilar K, Kleyer A, Simon D, Hueber A, Schett G: High Remission Rates in RA - Real Life Data from Bariticinib Arthritis Rheumatol. 2020;72 Suppl 10():
Baraliakos X, Kleyer A, Simon D, Koehm M, Ohrndorf S, Sewerin P: [Imaging of psoriatic arthritis and aspects of radiographic progression]. Z Rheumatol. 2020;79(1): 40-52
Simon D, Tascilar K, Kleyer A, Bayat S, Kampylafka E, Hueber A, Rech J, Schuster L, Engel K, Sticherling M, Schett G: STRUCTURAL ENTHESEAL LESIONS IN PSORIASIS PATIENTS ARE ASSOCIATED WITH AN INCREASED RISK OF PROGRESSION TO PSORIATIC ARTHRITIS - A PROSPECTIVE COHORT STUDY Ann Rheum Dis. 2020;79 Suppl 1(): 33-34
Bayat S, Simon D, Schuster L, Schett G, Kleyer A: Cinematic Rendering Enables Depiction of Bone Anabolic Effects in Patients Treated with Baricitinib Arthritis Rheumatol. 2020;72 Suppl 10():
Krusche M, Klemm P, Grahammer M, Mucke J, Vossen D, Kleyer A, Sewerin P, Knitza J: Acceptance, Usage, and Barriers of Electronic Patient-Reported Outcomes Among German Rheumatologists: Survey Study. JMIR mHealth uHealth. 2020;8(7): e18117
Adam S, Simon N, Steffen U, Andes FT, Scholtysek C, Müller DIH, Weidner D, Andreev D, Kleyer A, Culemann S, Hahn M, Schett G, Krönke G, Frey S, Hueber AJ: JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function. Sci Transl Med. 2020;12(530):
Valor-Méndez L, Hagen M, Kleyer A, Manger B, Schett G: Massive nodulous lesions on hands and feet in a RA patient and improvement under baricitinib treatment. RMD Open. 2020;6(3):
Andreev D, Liu M, Kachler K, Llerins Perez M, Kirchner P, Kölle J, Gießl A, Rauber S, Song R, Aust O, Grüneboom A, Kleyer A, Cañete JD, Ekici A, Ramming A, Finotto S, Schett G, Bozec A: Regulatory eosinophils induce the resolution of experimental arthritis and appear in remission state of human rheumatoid arthritis. Ann Rheum Dis. 2020;():
Renner N, Kleyer A, Krönke G, Simon D, Söllner S, Rech J, Uder M, Janka R, Schett G, Welsch GH, Pachowsky ML: T2 Mapping as a New Method for Quantitative Assessment of Cartilage Damage in Rheumatoid Arthritis. J Rheumatol. 2020;47(6): 820-825
Vodencarevic A, Tascilar K, Hartmann F, Reiser M, Bayat S, Knitza J, Valor L, Hagen M, Hueber A, Kleyer A, Zimmermann-Rittereiser M, Schett G, Simon D: PREDICTION OF FLARES FOR RHEUMATOID ARTHRITIS PATIENTS ON BIOLOGIC DMARDS USING MACHINE LEARNING AND SUBSETS OF VARIABLES AVAILABLE TO PHYSICIANS, PATIENTS AND PAYERS Ann Rheum Dis. 2020;79 Suppl 1(): 955-956
Krusche M, Klemm P, Grahammer M, Mucke J, Vossen D, Kleyer A, Sewerin P, Knitza J: ELECTRONIC PATIENT-REPORTED OUTCOMES: A SURVEY ABOUT ACCEPTANCE, USAGE AND BARRIERS AMONG GERMAN RHEUMATOLOGISTS Ann Rheum Dis. 2020;79 Suppl 1(): 551-552
Simon D, Tascilar K, Unbehend S, Bayat S, Berlin A, Liphardt AM, Meinderink T, Rech J, Hueber AJ, Schett G, Kleyer A: Bone Mass, Bone Microstructure and Biomechanics in Patients with Hand Osteoarthritis. J Bone Miner Res. 2020;35(9): 1695-1702
Simon D, Haschka J, Muschitz C, Kocijan A, Baierl A, Kleyer A, Schett G, Kapiotis S, Resch H, Sticherling M, Rech J, Kocijan R: Bone microstructure and volumetric bone mineral density in patients with hyperuricemia with and without psoriasis. Osteoporos Int. 2020;31(5): 931-939
Raimondo MG, Rauber S, Luber M, Rigau AR, Weber S, Anchang CG, Agarwal R, Soare A, Sticherling M, Rech J, Kleyer A, Distler J, Schett G, Ramming A: TYPE 3 INNATE LYMPHOID CELLS ARE KEY DRIVERS OF PSORIATIC ARTHRITIS Ann Rheum Dis. 2020;79 Suppl 1(): 1119-1120
Kleyer A, Pachowsky M, Schuster L, Valor-Mendez L, Schett G, Hueber A, Simon D: Understanding Ankylosing Spondylitis - Arthritis Rheumatol. 2020;72 Suppl 10():
Friedberger A, Figueiredo C, Grimm A, d'Oliveira I, Bäuerle T, Rech J, Kleyer A, Simon D, Uder M, Schett G, Engelke K: Quantification of hand muscle volume and composition in patients with rheumatoid arthritis, psoriatic arthritis and psoriasis. BMC Musculoskelet Disord. 2020;21(1):
Knitza J, Simon D, Lambrecht A, Raab C, Tascilar K, Hagen M, Kleyer A, Bayat S, Derungs A, Amft O, Schett G, Hueber AJ: Mobile Health Usage, Preferences, Barriers, and eHealth Literacy in Rheumatology: Patient Survey Study. JMIR Mhealth Uhealth. 2020;8(8):
Ellmann H, Bayat S, Araujo E, Manger B, Kleyer A, Cavallaro A, Lell M, Schenker H, Simon D, Tascilar K, Baraf HSB, Schett G, Rech J: Effects of Conventional Uric Acid-Lowering Therapy on Monosodium Urate Crystal Deposits Arthritis Rheumatol. 2020;72(1): 150-156
Bayat S, Simon D, Pecherstorfer C, Ellmann H, Figueiredo C, Englbrecht M, Hueber A, Kleyer A, Rech J, Schett G: FINE STRUCTURE ANALYSIS OF THE INTER-RELATION BETWEEN TOPHUS DEPOSITION AND BONE LESIONS IN GOUT USING A COMBINATION OF DUAL ENERGY AND HIGH-RESOLUTION CT Ann Rheum Dis. 2020;79 Suppl 1(): 1232-1232
Tajik N, Frech M, Schulz O, Schälter F, Lucas S, Azizov V, Dürholz K, Steffen F, Omata Y, Rings A, Bertog M, Rizzo A, Iljazovic A, Basic M, Kleyer A, Culemann S, Krönke G, Luo Y, Überla K, Gaipl US, Frey B, Strowig T, Sarter K, Bischoff SC, Wirtz S, Cañete JD, Ciccia F, Schett G, Zaiss MM: Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis. Nat Commun. 2020;11(1):
Pachowsky ML, Kleyer A, Wagner L, Langenbach A, Simon D, Janka R, May M, Welsch GH: Quantitative T2 Mapping Shows Increased Degeneration in Adjacent Intervertebral Discs Following Kyphoplasty. Cartilage. 2020;11(2): 152-159
Liphardt AM, Manger E, Liehr S, Bieniek L, Kleyer A, Simon D, Tascilar K, Sticherling M, Rech J, Schett G, Hueber AJ: Similar Impact of Psoriatic Arthritis and Rheumatoid Arthritis on Objective and Subjective Parameters of Hand Function. ACR Open Rheumatol. 2020;2(12): 734-740
Kampylafka E, Tascilar K, Lerchen V, Linz C, Sokolova M, Zekovic A, Kleyer A, Simon D, Rech J, Sticherling M, Schett G, Hueber AJ: Secukinumab leads to shifts from stage-based towards response-based disease clusters-comparative data from very early and established psoriatic arthritis. Arthritis Res Ther. 2020;22(1):
Rech J, Schenker H, Tascilar K, Hagen M, Mendez LV, Schoenau V, Sergeeva M, Prade J, Sulvakumar M, Konert L, Kleyer A, Simon D, Strobelt S, Behrens F, Baerwald C, Finzel S, Voll R, Hueber A, Feist E, Roesch J, da Silva JAP, Doerfler A, Damjanov N, Hess A, Schett G: Longitudinal Change in the Central Nervous System Pain Response After Treatment with Certolizumab or Placebo. a Post-hoc Analysis from the Pre-CEPRA Trial Arthritis Rheumatol. 2020;72 Suppl 10():
Maarseveen TD, Meinderink T, Reinders MJT, Knitza J, Huizinga TWJ, Kleyer A, Simon D, van den Akker EB, Knevel R: Machine Learning Electronic Health Record Identification of Patients with Rheumatoid Arthritis: Algorithm Pipeline Development and Validation Study. JMIR Med Inform. 2020;8(11):
Simon D, Tascilar K, Kleyer A, Bayat S, Kampylafka E, Sokolova M, Zekovic A, Hueber AJ, Rech J, Schuster L, Engel K, Sticherling M, Schett G: Structural entheseal lesions in patients with psoriasis are associated with an increased risk of progression to psoriatic arthritis. Arthritis Rheumatol. 2020;():
Kleyer A, Knitza J, Schett G, Manger B: Calcium pyrophosphate deposition disease induced inflammatory back pain. Rheumatology (Oxford). 2020;59(2): 456-456
Rech J, Tascilar K, Schenker H, Hagen M, Sergeeva M, Selvakumar M, Konerth L, Prade J, Strobelt S, Schonau V, Valor L, Hueber A, Simon D, Kleyer A, Behrens F, Baerwald C, Finzel S, Voll R, Feist E, Da Silva JAP, Doerfler A, Damjanov N, Hess A, Schett G: LONGITUDINAL CHANGE IN THE CENTRAL NERVOUS SYSTEM PAIN RESPONSE AFTER TREATMENT WITH CERTOLIZUMAB OR PLACEBO. A POST-HOC ANALYSIS FROM THE PRECEPRA TRIAL Ann Rheum Dis. 2020;79 Suppl 1(): 77-78
Knitza J, Callhoff J, Chehab G, Hueber A, Kiltz U, Kleyer A, Krusche M, Simon D, Specker C, Schneider M, Voormann A, Welcker M, Richter JG: [Position paper of the commission on digital rheumatology of the German Society of Rheumatology: tasks, targets and perspectives for a modern rheumatology]. Z Rheumatol. 2020;79(6): 562-569
Schenker H, Rech J, Tascilar K, Hagen M, Schoenau V, Sergeeva M, Selvakumar M, Konerth L, Prade J, Strobelt S, Valor L, Hueber A, Simon D, Kleyer A, Behrens F, Da Silva JAP, Baerwald C, Finzel S, Voll R, Feist E, Doerfler A, Damjanov N, Hess A, Schett G: CENTRAL NERVOUS SYSTEM PAIN RESPONSE AND COMPONENTS OF DISEASE ACTIVITY IN RA PATIENTS AFTER TREATMENT WITH CERTOLIZUMAB OR PLACEBO: A POST-HOC ANALYSIS FROM THE PRECEPRA TRIAL Ann Rheum Dis. 2020;79 Suppl 1(): 135-136
Simon D, Kleyer A, Tascilar K, Bayat S, Knitza J, Valor-Mendez L, Schweiger M, Schett G, Hueber A: High Impact Sports Leads to Inflammatory Responses at Entheseal Sites Results of the BEAT Study (Badminton Enthesitis Arthrosonography Study) Arthritis Rheumatol. 2020;72 Suppl 10():
Simon D, Kleyer A, Bui CD, Hueber A, Bang H, Ramming A, Rech J, Schett G: Micro-structural bone changes are associated with broad-spectrum autoimmunity and predict the onset of rheumatoid arthritis. Arthritis Rheumatol. 2020;():
Rech J, Tascilar K, Schenker H, Sergeeva M, Selvakumar M, Konerth L, Prade J, Strobelt S, Hagen M, Schonau V, Valor L, Hueber A, Simon D, Kleyer A, Behrens F, Da Silva JAP, Baerwald C, Finzel S, Voll R, Feist E, Doerfler A, Damjanov N, Hess A, Schett G: PREDICTION OF RESPONSE TO CERTOLIZUMAB PEGOL TREATMENT BY FUNCTIONAL MRI OF THE BRAIN: AN INTERNATIONAL, MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL (PRECEPRA) Ann Rheum Dis. 2020;79 Suppl 1(): 952-952
Simon D, Tascilar K, Kronke G, Kleyer A, Zaiss M, Heppt F, Meder C, Atreya R, Klenske E, Dietrich P, Abdullah A, Kliem T, Corte G, Morf H, Leppkes M, Kremer A, Ramming A, Pachowsky M, Schuch F, Ronneberger M, Kleinert S, Maier C, Hueber A, Manger K, Manger B, Berking C, Tenbusch M, Ueberla K, Sticherling M, Neurath M, Schett G: Patients Receiving Cytokine Inhibitors Have Low Prevalence of SARS-CoV-2 Infection Arthritis Rheumatol. 2020;72 Suppl 10():
Simon D, Tascilar K, Kleyer A, Bayat S, Kampylafka E, Hueber A, Rech J, Schuster L, Engel K, Sticherling M, Schett G: Structural Entheseal Lesions in Psoriasis Patients Are Associated with an Increased Risk Ofprogression to Psoriatic Arthritis - A Prospective Cohort Study Arthritis Rheumatol. 2020;72 Suppl 10():
Knitza J, Mohn J, Bergmann C, Kampylafka E, Hagen M, Bohr D, Araujo E, Englbrecht M, Simon D, Kleyer A, Meinderink T, Vorbruggen W, Von der Decken CB, Kleinert S, Ramming A, Distler J, Bartz-Bazzanella P, Schett G, Hueber A, Welcker M: REAL-WORLD EFFECTIVENESS AND PERCEIVED USEFULNESS OF SYMPTOM CHECKERS IN RHEUMATOLOGY: INTERIM REPORT FROM THE PROSPECTIVE MULTICENTER BETTER STUDY Ann Rheum Dis. 2020;79 Suppl 1(): 1957-1957
Rech J, Schenker H, Tascilar K, Hagen M, Kleyer A, Simon D, Mendez LV, Schoenau V, Prade J, Sergeeva M, Sulvakumar M, Strobelt S, Konerth L, Behrens F, Baerwald C, Finzel S, Voll R, Hueber A, Roesch J, Feist E, da Silva JAP, Doerfler A, Damjanov N, Hess A, Schett G: Brain fMRI Predicts Responses to Certolizumab Pegol in RA. an International, Multi-center, Randomized, Double-blind, Placebocontrolled Trial (PreCePRA) Arthritis Rheumatol. 2020;72 Suppl 10():
Pecherstorfer C, Simon D, Unbehend S, Ellmann H, Englbrecht M, Hartmann F, Figueiredo C, Hueber A, Haschka J, Kocijan R, Kleyer A, Schett G, Rech J, Bayat S: A Detailed Analysis of the Association between Urate Deposition and Erosions and Osteophytes in Gout. ACR Open Rheumatol. 2020;2(10): 565-572
Treutlein C, Bäuerle T, Nagel AM, Guermazi A, Kleyer A, Simon D, Schett G, Hepp T, Uder M, Roemer FW: Comprehensive assessment of knee joint synovitis at 7 T MRI using contrast-enhanced and non-enhanced sequences. BMC Musculoskelet Disord. 2020;21(1):
Kampylafka E, Tascilar K, Lerchen V, Linz C, Sokolova M, Zekovic A, Kleyer A, Simon D, Rech J, Sticherling M, Schett G, Hueber A: Interleukin-17 Blockade Leads to Shifts from Stage-based Towards Response-based Disease Clusters- Comparative Data from Very Early and Established Psoriatic Arthritis Arthritis Rheumatol. 2020;72 Suppl 10():
Liphardt AM, Manger E, Liehr S, Bieniek L, Kleyer A, Simon D, Tascilar K, Sticherling M, Rech J, Schett G, Hueber A: Similar Impact of Psoriatic Arthritis and Rheumatoid Arthritis on Objective and Subjective Parameters of Hand Function Arthritis Rheumatol. 2020;72 Suppl 10():
Schmidkonz C, Rauber S, Atzinger A, Agarwal R, Götz TI, Soare A, Cordes M, Prante O, Bergmann C, Kleyer A, Ritt P, Maschauer S, Hennig P, Toms J, Köhner M, Manger B, Stone JH, Haberkorn U, Baeuerle T, Distler JHW, Agaimy A, Kuwert T, Schett G, Ramming A: Disentangling inflammatory from fibrotic disease activity by fibroblast activation protein imaging. Ann Rheum Dis. 2020;79(11): 1485-1491
Bayat S, Tascilar K, Kaufmann V, Kleyer A, Simon D, Knitza J, Hartmann F, Adam S, Hueber A, Schett G: HIGH REMISSION RATES IN RA - REAL LIFE DATA FROM BARITICINIB Ann Rheum Dis. 2020;79 Suppl 1(): 1459-1460
Bayat S, Ellmann H, Araujo E, Manger B, Hagen M, Kleyer A, Cavallaro A, Lell M, Schenker H, Simon D, Tascilar K, Baraf HSB, Schett G, Rech J: SIZE MATTERS - EXTENT OF MONOSODIUM URATE DEPOSITS BUT NOT SERUM URATE LEVEL PREDICTS COMPLETE RESOLUTION OF MONOSODIUM URATE CRYSTAL DEPOSITS IN PATIENTS WITH GOUT Ann Rheum Dis. 2019;78(): 1295-1296
Simon D, Kleyer A, Bayat S, Tascilar K, Kampylafka E, Meinderink T, Schuster L, Petrov R, Liphardt AM, Rech J, Schett G, Hueber AJ: Effect of disease-modifying anti-rheumatic drugs on bone structure and strength in psoriatic arthritis patients Arthritis Res Ther. 2019;21():
Stephan M, Tascilar K, Hagen M, Haschka J, Reiser M, Hartmann F, Kleyer A, Hueber A, Manger B, Figuereido C, Cobra J, Tony HP, Finzel S, Kleinert S, Wendler J, Schuch F, Ronneberger M, Feuchtenberger M, Fleck M, Manger K, Ochs W, Schmitt-Haendle M, Lorenz HM, Nuesslein H, Alten R, Henes J, Krueger K, Schett G, Rech J: PHYSICAL FUNCTION IN RA PATIENTS IN REMISSION UNDERGOING TAPERING AND/OR STOPPING OF DMARDS Ann Rheum Dis. 2019;78(): 321-322
Knitza J, Kleyer A, Schett G, Manger B: Chondrocalcinosis: idiopathic or manifestation of rare metabolic diseases? Orthopade. 2019;48(11): 949-956
Knitza J, Vossen D, Geffken I, Krusche M, Meyer M, Sewerin P, Kleyer A, Hueber AJ, Arbeitskreis Junge Rheumatologen: Use of medical apps and online platforms among German rheumatologists Results of the 2016 and 2018 DGRh conference surveys and research conducted by rheumadocs Z Rheumatol. 2019;78(9): 839-846
Simon D, Bayat S, Tascilar K, Kampylafka E, Meinderink T, Schuster L, Liphardt AM, Rech J, Hueber A, Schett G, Kleyer A: EFFECT OF DISEASE-MODIFYING ANTI-RHEUMATIC DRUGS ON BONE STRUCTURE AND STRENGTH IN PSORIATIC ARTHRITIS PATIENTS Ann Rheum Dis. 2019;78(): 1287-1287
Kampylafka E, Simon D, d'Oliveira I, Linz C, Lerchen V, Englbrecht M, Rech J, Kleyer A, Sticherling M, Schett G, Hueber AJ: Disease interception with interleukin-17 inhibition in high-risk psoriasis patients with subclinical joint inflammation-data from the prospective IVEPSA study. Arthritis Res Ther. 2019;21(1):
Simon D, Schett G, Kleyer A: Clinical Images: Development of joint erosions in the preclinical phase of rheumatoid arthritis depicted by cinematic rendering Arthritis Rheumatol. 2019;71(9): 1592-1592
Engelke K, Figueiredo C, Kleyer A, Simon D, Schett G: VALUE AND LIMITATIONS IN HR-PQCT IMAGING IN CHRONIC ARTHRITIS. CURRENT STATUS AND FUTURE DIRECTIONS Osteoporos Int. 2019;30(): S230-S231
Kleyer A, Simon D, Hartmann F, Schuster L, Hueber AJ: "Virtual Rheumatology" A new Teaching Concept for the Rheumatology of Future? Z Rheumatol. 2019;78(2): 112-115
Simon D, Kleyer A, Adinolfi A, Willeit J, Kiechl S, Gasperi N, Schett G, Dejaco C, Iagnocco A, D'agostino MA: KNEE JOINT PAIN IN AN ELDERLY, HEALTHY POPULATION IS ASSOCIATED WITH INFLAMMATORY ARTICULAR AND ENTHESEAL CHANGES DETECTED BY ULTRASOUND Ann Rheum Dis. 2019;78(): 597-598
Araujo EG, Englbrecht M, Hoepken S, Finzel S, Kampylafka E, Kleyer A, Bayat S, Schoenau V, Hueber A, Rech J, Schett G: Effects of ustekinumab versus tumor necrosis factor inhibition on enthesitis: Results from the enthesial clearance in psoriatic arthritis (ECLIPSA) study. Semin Arthritis Rheum. 2019;48(4): 632-637
Simon D, Berlin A, Tascilar K, Bayat S, Engelke K, Rech J, Figuereido C, Hueber A, Schett G, Kleyer A: THE PHYSIOLOGICAL FINGER JOINT ARCHITECTURE - AGE-RELATED INCREASE OF EROSIONS AND OSTEOPHYTES IN THE JOINTS OF HEALTHY INDIVIDUALS Ann Rheum Dis. 2019;78(): 602-603
Liphardt AM, Liehr S, Manger E, Bieniek L, Kleyer A, Simon D, Tascilar K, Sticherling M, Rech J, Schett G, Hueber A: HAND FUNCTION IS IMPAIRED IN PATIENTS WITH RHEUMATOID ARTHRITIS, PSORIATIC ARTHRITIS, AND PSORIASIS COMPARED TO HEALTHY CONTROLS Ann Rheum Dis. 2019;78(): 2126-2126
Berlin A, Simon D, Tascilar K, Figueiredo C, Bayat S, Finzel S, Klaus E, Rech J, Hueber AJ, Kleyer A, Schett G: The ageing joint-standard age- and sex-related values of bone erosions and osteophytes in the hand joints of healthy individuals. Osteoarthritis Cartilage. 2019;27(7): 1043-1047
Gelse K, Biggemann J, Stumpf M, Halmheu M, Grüneboom A, Kleyer A, Scholtysek C, Pachowsky ML, Hueber A, Krönke G, Fey T: Modular Lattice Constructs for Biological Joint Resurfacing. Tissue Eng Part A. 2019;25(13-14): 1053-1062
Simon D, Tascilar K, Unbehend S, Bayat S, Meinderink T, Berlin A, Rech J, Hueber A, Schett G, Kleyer A: IMPACT OF PRIMARY HAND OSTEOARTHRITIS ON MICROSTRUCTURE AND BIOMECHANICS IN FINGER JOINTS Ann Rheum Dis. 2019;78(): 1868-1868
Kleyer A, Simon D, Bui CD, Hueber A, Bang H, Ramming A, Rech J, Kroenke G, Schett G: MICRO-STRUCTURAL CHANGES ASSOCIATED WITH ANTI-CITRULLINATED VIMENTIN AUTOIMMUNITY IN RA-AT-RISK INDIVIDUALS PRECIPITATE THE ONSET OF RHEUMATOID ARTHRITIS Ann Rheum Dis. 2019;78(): 133-133
Culemann S, Grueneboom A, Angel Nicolas-Avila JA, Weidner D, Laemmle KF, Rothe T, Quintana JA, Kirchner P, Krljanac B, Eberhardt M, Ferrazzi F, Kretzschmar E, Schicht M, Fischer K, Gelse K, Faas M, Pfeifle R, Ackermann JA, Pachowsky M, Renner N, Simon D, Haseloff RF, Ekici AB, Baeuerle T, Blasig IE, Vera J, Voehringer D, Kleyer A, Paulsen F, Schett G, Hidalgo A, Kroenke G: Locally renewing resident synovial macrophages provide a protective barrier for the joint. Nature. 2019;572(7771): 670-675
Knitza J, Raab C, Lambrecht A, Simon D, Hagen M, Bayat S, Schett G, Kleyer A, Hueber A: The Urge for Mobile Apps in Rheumatology - a German Patient Perspective Arthritis Rheumatol. 2019;71():
Hagen M, Englbrecht M, Haschka J, Reiser M, Kleyer A, Hueber A, Manger B, Figueiredo C, Cobra JF, Tony HP, Finzel S, Kleinert S, Wendler J, Schuch F, Ronneberger M, Feuchtenberger M, Fleck M, Manger K, Ochs W, Lorenz HM, Nüsslein H, Alten R, Henes J, Krüger K, Schett G, Rech J: Cost-effective Tapering Algorithm in Patients with Rheumatoid Arthritis: Combination of Multibiomarker Disease Activity Score and Autoantibody Status. J Rheumatol. 2019;46(5): 460-466
Kampylafka E, Oliveira I, Linz C, Lerchen V, Englbrecht M, Simon D, Rech J, Kleyer A, Schett G, Sticherling M, Hueber AJ: Interleukin 17 Blockade in Psoriasis Patients with Subclinical Joint Inflammation- Prospective Open Study to Influence the Course of the Disease by means of Secukinumab J Dtsch Dermatol Ges. 2019;17(): 127-128
Kampylafka E, Englbrecht M, Tascilar K, Lerchen V, Linz C, Kleyer A, Simon D, Rech J, Schett G, Hueber A: COMPARATIVE CHANGE IN QUALITY OF LIFE MEASURES IN PRECLINICAL AND ESTABLISHED PSORIATIC ARTHRITIS PATIENTSUNDER SECUKINUMAB TREATMENT. DATA DERIVED FROM THE PROSPECTIVE OPEN LABEL PSARTROS STUDY Ann Rheum Dis. 2019;78(): 1845-1845
Hagen M, Tascilar K, Reiser M, Haschka J, Kleyer A, Valor L, Manger B, Schett G, Rech J: Prediction of Disease Relapses by Multi-biomarker Disease Activity Score and Autoantibody Status in RA Patients Tapering DMARD Treatment in Stable Remission Arthritis Rheumatol. 2019;71():
Krusche M, Sewerin P, Kleyer A, Mucke J, Vossen D, Morf H: Specialist training quo vadis? Z Rheumatol. 2019;78(8): 692-697
Haschka J, Simon D, Bayat S, Kleyer A, Kampylafka E, Hueber A, Muschitz C, Skalicky S, Hackl M, Resch H, Schett G, Kocijan R, Rech J: Identification of Circulating MicroRNA Signatures in Patients with Psoriasis and Psoriatic Arthritis to Develop Novel Strategies for Early Diagnosis of a Bone and Joint Involvement Arthritis Rheumatol. 2019;71():
Valor L, Hagen M, Reiser M, Kleyer A, Hartmann F, Manger B, Schett G, Rech J, Tascilar K, Haschka J, Englbrecht M, Hueber A, Figueiredo C, Fogagnolo J, Tony HP, Finzel S, Kleinert S, Wendler J, Schuch F, Ronneberger M, Feuchtenberger M, Fleck M, Manger K, Ochs W, Schmitt-Haendle M, Lorenz HM, Nuesslein H, Alten R, Henes J, Krueger K, Retro: FACTORS ASSOCIATED WITH PERSISTENT DRUG-FREE REMISSION IN PATIENTS WITH RHEUMATOID ARTHRITIS Ann Rheum Dis. 2019;78(): 730-730
Knitza J, Tascilar K, Messner EM, Meyer M, Vossen D, Pulla A, Bosch P, Kittler J, Kleyer A, Sewerin P, Mucke J, Haase I, Simon D, Krusche M: Mobile Apps in Rheumatology: Review and Analysis Using the Mobile App Rating Scale (MARS) Arthritis Rheumatol. 2019;71():
Knitza J, Tascilar K, Messner EM, Meyer M, Vossen D, Pulla A, Bosch P, Kittler J, Kleyer A, Sewerin P, Mucke J, Haase I, Simon D, Krusche M: German Mobile Apps in Rheumatology: Review and Analysis Using the Mobile Application Rating Scale (MARS) JMIR mHealth uHealth. 2019;7(8):
Schett G, Simon D, Hueber A, Bang H, Rech J, Kroenke G, Kleyer A: Anti-citrullinated Vimentin Antibodies Are Associated to Early Deterioration of Cortical Bone and Volumetric Bone Mineral Density in Finger Joints in RA-at-risk Patients Arthritis Rheumatol. 2019;71():
Vodencarevic A, Simon D, Hartmann F, Reiser M, Hueber A, Tascilar K, Kleyer A, Zimmermann-Rittereiser M, Schett G: Individually Tailored Predictions of Flare Probability for Rheumatoid Arthritis Patients on Biologic DMARDs Based on Machine Learning Stacking Meta-Classifier Arthritis Rheumatol. 2019;71():
Valor L, Hagen M, Reiser M, Hartmann F, Kleyer A, Manger B, Schett G, Rech J, Tascilar K: Factors Associated with Persistent Drug-free Remission in Patients with Rheumatoid Arthritis Arthritis Rheumatol. 2019;71():
Sewerin P, Ostendorf B, Hueber AJ, Kleyer A: [Big data in imaging]. Z Rheumatol. 2018;77(3): 203-208
Simon D, Kleyer A, Faustini F, Englbrecht M, Haschka J, Berlin A, Kraus S, Hueber AJ, Kocijan R, Sticherling M, Rech J, Schett G: Simultaneous quantification of bone erosions and enthesiophytes in the joints of patients with psoriasis or psoriatic arthritis - effects of age and disease duration. Arthritis Res Ther. 2018;20(1):
Renner N, Kleyer A, Kroenke G, Simon D, Rech J, Schett G, Welsch G, Pachowsky ML: CARTILAGE DAMAGE QUANTITATIVELY ASSESSED BY MRI USING T2 MAPPING IN CCP-POSITIVE RA PATIENTS Ann Rheum Dis. 2018;77(): 1181-1181
Stemmler F, Simon D, Liphardt AM, Englbrecht M, Rech J, Hueber AJ, Engelke K, Schett G, Kleyer A: Biomechanical properties of bone are impaired in patients with ACPA-positive rheumatoid arthritis and associated with the occurrence of fractures. Ann Rheum Dis. 2018;77(7): 973-980
Kamoylafka E, Oliveira ID, Linz C, Lerchen V, Englbrecht M, Simon D, Sticherling M, Rech J, Kleyer A, Schett G, Hueber AJ: DISEASE INTERCEPTION IN PSORIASIS PATIENTS WITH SUBCLINICAL JOINT INFLAMMATION BY INTERLEUKIN 17 INHIBITION WITH SECUKINUMAB - DATA FROM A PROSPECTIVE OPEN LABEL STUDY Ann Rheum Dis. 2018;77(): 199-199
Manger K, von Streitberg U, Seitz G, Kleyer A, Manger B: Hard palate hyperpigmentation-a rare side effect of antimalarials. Arthritis Rheumatol. 2018;70(1): 152
Gasperi N, Adinolfi A, Kleyer A, Hagen M, Gasperi C, Weger M, Kiechl S, Willeit J, Schett G, Iagnocco A, Gasperi A, Mayr A, Dejaco C: What Characterizes Osteoarthritis: Ultrasound-Detected Inflammation but Not Osteophytes Is More Common in Hand Osteoarthritis Than in Painless Bony Enlargements Arthritis Rheumatol. 2018;70():
Kampylafka E, Oliveira I, Linz C, Lerchen V, Englbrecht M, Simon D, Sticherling M, Rech J, Kleyer A, Schett G, Hueber AJ: Disease Interception in Psoriasis Patients with Subclinical Joint Inflammation By Interleukin 17 Inhibition with Secukinumab - Data from a Prospective Open Label Study Arthritis Rheumatol. 2018;70():
Soare A, Weber S, Maul L, Rauber S, Gheorghiu AM, Luber M, Houssni I, Kleyer A, von Pickardt G, Gado M, Simon D, Rech J, Schett G, Distler JHW, Ramming A: Cutting Edge: Homeostasis of Innate Lymphoid Cells Is Imbalanced in Psoriatic Arthritis. J Immunol. 2018;200(4): 1249-1254
Soare A, Weber S, Maul L, Rauber S, Gheorghiu AM, Houssni I, Kleyer A, Luber M, Rech J, Schett G, Distler J, Ramming A: INNATE LYMPHOID CELLS CORRELATE WITH DISEASE ACTIVITY AND BONE REMODELLING IN PSORIATIC ARTHRITIS Ann Rheum Dis. 2018;77(): 116-116
Simon D, Unbehend S, Bayat S, Rech J, Hueber AJ, Schett G, Kleyer A: The Influence of Hand Osteoarthritis on Bone Microstructure and Biomechanical Properties of Radial Bone Arthritis Rheumatol. 2018;70():
Figueiredo CP, Kleyer A, Simon D, Stemmler F, d'Oliveira I, Weissenfels A, Museyko O, Friedberger A, Hueber AJ, Haschka J, Englbrecht M, Pereira RMR, Rech J, Schett G, Engelke K: Methods for segmentation of rheumatoid arthritis bone erosions in high-resolution peripheral quantitative computed tomography (HR-pQCT). Semin Arthritis Rheum. 2018;47(5): 611-618
Neumann A, Haschka J, Kleyer A, Schuster L, Englbrecht M, Berlin A, Figueiredo CP, Simon D, Muschitz C, Kocijan R, Resch H, Rech J, Schett G: Cortical bone loss is an early feature of nonradiographic axial spondyloarthritis. Arthritis Res Ther. 2018;20(1):
Kampylafka E, d'Oliveira I, Linz C, Lerchen V, Stemmler F, Simon D, Englbrecht M, Sticherling M, Rech J, Kleyer A, Schett G, Hueber AJ: Resolution of synovitis and arrest of catabolic and anabolic bone changes in patients with psoriatic arthritis by IL-17A blockade with secukinumab: results from the prospective PSARTROS study. Arthritis Res Ther. 2018;20(1):
Simon D, Kleyer A, Englbrecht M, Stemmler F, Simon C, Berlin A, Kocijan R, Haschka J, Hirschmann S, Atreya R, Neurath MF, Sticherling M, Rech J, Hueber AJ, Engelke K, Schett G: A comparative analysis of articular bone in large cohort of patients with chronic inflammatory diseases of the joints, the gut and the skin. Bone. 2018;116(): 87-93
Erhard J, Hagen M, Englbrecht M, Haschka J, Reiser M, Kleyer A, Hueber AJ, Manger B, Figueiredo C, Cobra JF, Tony HP, Finzel S, Kleinert S, Wendler J, Schuch F, Ronneberger M, Feuchtenberger M, Fleck M, Manger K, Ochs W, Schmitt-Haendle M, Lorenz H, Nuesslein H, Alten R, Henes J, Krueger K, Schett G, Rech J: LOOSING DAS28-ESR, BUT STAYING IN BOOLEAN REMISSION-IS IT POSSIBLE? DATA FROM THE PROSPECTIVE, RANDOMISED RETRO TRIAL ON RHEUMATOID ARTHRITIS PATIENTS IN STABLE REMISSION Ann Rheum Dis. 2018;77(): 1307-1308
Stemmler F, Simon D, Liphardt AM, Englbrecht M, Rech J, Hueber A, Engelke K, Schett G, Kleyer A: BIOMECHANICAL PROPERTIES OF RADIAL BONE ARE DIFFERENT BETWEEN AUTO-ANTIBODY POSITIVE AND NEGATIVE RHEUMATOID ARTHRITIS Ann Rheum Dis. 2018;77(): 804-804

PD Dr. A. Kleyer

Medicine 3

Publications: PD Dr. med. A. Kleyer