Publications: Prof. Dr. med. G. Krönke
- Humoral and Cellular Immune Responses to SARS-CoV-2 Infection and Vaccination in Autoimmune Disease Patients With B Cell Depletion. Arthritis Rheumatol. 2022;74(1): 33-37
- Impact of Cytokine Inhibitor Therapy on the Prevalence, Seroconversion Rate, and Longevity of the Humoral Immune Response Against SARS-CoV-2 in an Unvaccinated Cohort. Arthritis Rheumatol. 2022;74(5): 783-790
- TELERA-Asynchronous TELEmedicine for Patients With Rheumatoid Arthritis: Study Protocol for a Prospective, Multi-Center, Randomized Controlled Trial. Front Med (Lausanne). 2021;8():
- Deep learning methods allow fully automated segmentation of metacarpal bones to quantify volumetric bone mineral density. Sci Rep. 2021;11(1):
- SPATIOTEMPORAL DYNAMICS OF BONE LOSS BEFORE AND AFTER THE ONSET OF RHEUMATOID ARTHRITIS Ann Rheum Dis. 2021;80 Suppl 1(): 88-89
- An advanced optical clearing protocol allows label-free detection of tissue necrosis via multiphoton microscopy in injured whole muscle. Theranostics. 2021;11(6): 2876-2891
- PATIENTS WITH IMMUNE MEDIATED INFLAMMATORY DISEASES ARE OVERREPRESENTED IN LOW-FREQUENCY VIRAL SYMPTOM CLUSTERS Ann Rheum Dis. 2021;80 Suppl 1(): 996-997
- Optoacoustic Imaging in Inflammation. Biomedicines. 2021;9(5):
- THE IMPACT OF IL-17A THERAPY ON IGG SIALYLATION IN HUMANS Ann Rheum Dis. 2021;80 Suppl 1(): 1042-1043
- More on CD19-CAR T Cells in Systemic Lupus Erythematosus. Reply. N Engl J Med. 2021;385(19):
- DIFFERENTIAL DIAGNOSIS OF RA AND PSA USING NEURAL NETWORKS ON THREE-DIMENSIONAL BONE SHAPE OF FINGER JOINTS Ann Rheum Dis. 2021;80 Suppl 1(): 86-87
- Hydroxyapatite-Coated SPIONs and Their Influence on Cytokine Release. Int J Mol Sci. 2021;22(8):
- SARS-CoV-2 vaccination responses in untreated, conventionally treated and anticytokine-treated patients with immune-mediated inflammatory diseases. Ann Rheum Dis. 2021;80(10): 1312-1316
- CD19-Targeted CAR T Cells in Refractory Systemic Lupus Erythematosus. N Engl J Med. 2021;385(6): 567-569
- Advanced machine learning for predicting individual risk of flares in rheumatoid arthritis patients tapering biologic drugs. Arthritis Res Ther. 2021;23(1):
- Efficacy and safety of SARS-CoV-2 revaccination in non-responders with immune-mediated inflammatory disease. Ann Rheum Dis. 2021;():
- IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation. Immunity. 2021;54(11): 2531-2546.e5
- TYK2 inhibition and its potential in the treatment of chronic inflammatory immune diseases. J Dtsch Dermatol Ges. 2021;19(10): 1409-1420
- [Protective macrophages : New insights into the role of synovial macrophages in inflammatory joint diseases]. Z Rheumatol. 2021;80(10): 966-971
- Upregulation of CCR4 in activated CD8+ T cells indicates enhanced lung homing in patients with severe acute SARS-CoV-2 infection. Eur J Immunol. 2021;51(6): 1436-1448
- More on CD19-CAR T Cells in Systemic Lupus Erythematosus N Engl J Med. 2021;385(19):
- The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts. Immunity. 2021;54(5): 1002-1021.e10
- JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function. Sci Transl Med. 2020;12(530):
- PPARβ/δ-dependent MSC metabolism determines their immunoregulatory properties. Sci Rep. 2020;10(1):
- Environmental arginine controls multinuclear giant cell metabolism and formation Nat Commun. 2020;11(1):
- T2 Mapping as a New Method for Quantitative Assessment of Cartilage Damage in Rheumatoid Arthritis. J Rheumatol. 2020;47(6): 820-825
- Identifying 'non-progressors' among patients with arthralgia. Nat Rev Rheumatol. 2020;16(5): 251-252
- Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis. Nat Commun. 2020;11(1):
- Formation of atherosclerotic lesions is independent of eosinophils in male mice. Atherosclerosis. 2020;311(): 67-72
- Patients Receiving Cytokine Inhibitors Have Low Prevalence of SARS-CoV-2 Infection Arthritis Rheumatol. 2020;72 Suppl 10():
- Metabolic reprogramming of osteoclasts represents a therapeutic target during the treatment of osteoporosis. Sci Rep. 2020;10(1):
- Osteocyte necrosis triggers osteoclast-mediated bone loss through macrophage-inducible C-type lectin. J Clin Invest. 2020;130(9): 4811-4830
- Chronic Peripheral Inflammation Causes a Region-Specific Myeloid Response in the Central Nervous System. Cell Rep. 2020;30(12): 4082-4095.e6
- PPARδ-mediated mitochondrial rewiring of osteoblasts determines bone mass. Sci Rep. 2020;10(1):
- Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion. Nat Commun. 2020;11(1):
- THE ROLE OF THE IL-23/TH17 AXIS AS MODULATOR OF B CELL-MEDIATED (AUTO)IMMUNE RESPONSES Ann Rheum Dis. 2019;78(): A42-A42
- Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity Proc Natl Acad Sci U S A. 2019;116(16): 8038-8047
- Important Role of CD11c(+) Cells in Inflammatory Arthritis Arthritis Rheumatol. 2019;71():
- IMPORTANT ROLE OF CD11C+CELLSIN INFLAMMATORY ARTHRITIS Ann Rheum Dis. 2019;78(): 1094-1094
- Structural insights into heme binding to IL-36 alpha proinflammatory cytokine Sci Rep. 2019;9():
- REGULATION OF AUTOANTIBODY ACTIVITY BY T CELL SUBSETS Ann Rheum Dis. 2019;78(): 30-30
- IMPORTANT ROLE OF DENDRITIC CELLS IN INFLAMMATORY ARTHRITIS Ann Rheum Dis. 2019;78(): A54-A55
- Modular Lattice Constructs for Biological Joint Resurfacing. Tissue Eng Part A. 2019;25(13-14): 1053-1062
- A network of trans-cortical capillaries as mainstay for blood circulation in long bones. Nat Metab. 2019;1(2): 236-250
- MICRO-STRUCTURAL CHANGES ASSOCIATED WITH ANTI-CITRULLINATED VIMENTIN AUTOIMMUNITY IN RA-AT-RISK INDIVIDUALS PRECIPITATE THE ONSET OF RHEUMATOID ARTHRITIS Ann Rheum Dis. 2019;78(): 133-133
- RELM alpha-expressing macrophages protect against fatal lung damage and reduce parasite burden during helminth infection Sci Immunol. 2019;4(35):
- Enzymatically oxidized phospholipids assume center stage as essential regulators of innate immunity and cell death Sci Signal. 2019;12(574):
- JAK-INHIBITORS TOFACITINIB AND BARICITINIB IMPROVE PATHOLOGICAL BONE LOSS IN VIVO Ann Rheum Dis. 2019;78(): 110-110
- JAK-INHIBITION BY BARICITINIB AND TOFACITINIB AMELIORATES PATHOLOGICAL BONE LOSS Ann Rheum Dis. 2019;78(): A65-A65
- Locally renewing resident synovial macrophages provide a protective barrier for the joint. Nature. 2019;572(7771): 670-675
- Anti-citrullinated Vimentin Antibodies Are Associated to Early Deterioration of Cortical Bone and Volumetric Bone Mineral Density in Finger Joints in RA-at-risk Patients Arthritis Rheumatol. 2019;71():
- Origin and function of synovial macrophage subsets during inflammatory joint disease Adv Immunol. 2019;143(): 75-98
- The involvement of Toll-like receptor 9 in the pathogenesis of erosive autoimmune arthritis. J Cell Mol Med. 2018;22(9): 4399-4409
- Glucocorticoid receptor in stromal cells is essential for glucocorticoid-mediated suppression of inflammation in arthritis. Ann Rheum Dis. 2018;77(11): 1610-1618
- [Osteoimmunology-IMMUNOBONE : Regulation of bone by inflammation]. Z Rheumatol. 2018;77(Suppl 1): 12-15
- Group 2 Innate Lymphoid Cells Attenuate Inflammatory Arthritis and Protect from Bone Destruction in Mice. Cell Rep. 2018;24(1): 169-180
- [Mutual influence of immune system and bones]. Z Rheumatol. 2018;77(Suppl 1): 8-11
- Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss. Nat Commun. 2018;9(1): 55
- Eosinophils are not essential for maintenance of murine plasma cells in the bone marrow. Eur J Immunol. 2018;48(5): 822-828
- Correction: Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease. J Exp Med. 2018;215(3):
- CD11C+DENDTRITIC CELLS IN INFLAMMATORY ARTHRITIS Ann Rheum Dis. 2018;77(): 256-256
- Estrogen induces St6gal1 expression and increases IgG sialylation in mice and patients with rheumatoid arthritis: a potential explanation for the increased risk of rheumatoid arthritis in postmenopausal women. Arthritis Res Ther. 2018;20(1):
- Autoantibodies Recognizing Secondary NEcrotic Cells Promote Neutrophilic Phagocytosis and Identify Patients With Systemic Lupus Erythematosus Front Immunol. 2018;9():
- IMPORTANT ROLE OF CD11C+DENDRITIC CELLS IN INFLAMMATORY ARTHRITIS Ann Rheum Dis. 2018;77(): A36-A37
- NR4A1 Regulates Motility of Osteoclast Precursors and Serves as Target for the Modulation of Systemic Bone Turnover. J Bone Miner Res. 2018;33(11): 2035-2047
- The B cell response to citrullinated antigens in the development of rheumatoid arthritis. Nat Rev Rheumatol. 2018;14(3): 157-169
- CARTILAGE DAMAGE QUANTITATIVELY ASSESSED BY MRI USING T2 MAPPING IN CCP-POSITIVE RA PATIENTS Ann Rheum Dis. 2018;77(): 1181-1181
- IMPACT OF TOLL-LIKE RECEPTOR 9 IN INFLAMMATORY ARTHRITIS AND OSTEOCLASTOGENESIS Ann Rheum Dis. 2017;76(): A86-A86
- Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease. Nat Immunol. 2017;18(1): 104-113
- The Nuclear Receptor Nr4a1 Acts as a Microglia Rheostat and Serves as a Therapeutic Target in Autoimmune-Driven Central Nervous System Inflammation. J Immunol. 2017;198(10): 3878-3885
- The double-edged role of 12/15-lipoxygenase during inflammation and immunity. Biochim Biophys Acta Mol Cell Biol Lipids. 2017;1862(4): 371-381
- Full Length Interleukin 33 Aggravates Radiation-Induced Skin Reaction. Front Immunol. 2017;8(): 722
- DIFFERENTIAL SCAVENGING OF APOPTOTIC CELLS AND BACTERIA Ann Rheum Dis. 2017;76(): 15-15
- Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease. J Exp Med. 2017;214(7): 2121-2138
- Corrigendum to "Fc-gamma receptors are not involved in cartilage damage during experimental osteoarthritis" [Osteoarthritis Cartilage 23 (2015) 1221-1225]. Osteoarthritis Cartilage. 2017;25(6): 995
- Short chain fatty acids are potent regulators of systemic bone mass and protect for pathological bone loss by inhibiting osteoclasts Eur J Immunol. 2017;47(): 217-217
- Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis. Sci Signal. 2017;10(507):
- ESTROGEN INFLUENCES THE SIALYLATION PROFILE AND INFLAMMATORY PROPERTIES OF ANTIBODIES - A POTENTIAL EXPLANATION FOR THE SEX DIFFERENCES AND INCREASED RISK FOR RA IN POSTMENOPAUSAL WOMEN Ann Rheum Dis. 2017;76(): 775-775
- Runx2 mediated Induction of Novel Targets ST2 and Runx3 Leads to Cooperative Regulation of Hypertrophic Differentiation in ATDC5 Chondrocytes. Sci Rep. 2017;7(1): 17947
- Development of three-dimensional prints of arthritic joints for supporting patients' awareness to structural damage. Arthritis Res Ther. 2017;19(1): 34
- Increased Cartilage Damage in Metacarpophalangeal Joints of ACPA Positive Rheumatoid Arthritis (RA) Patients Using T2 Mapping in 3 Tesla Magnetresonance Imaging (MRI) Arthritis Rheumatol. 2017;69():
- Novel mechanism mediated by the IL23/Th17 axis contributing to auto-immune arthritis Eur J Immunol. 2017;47(): 141-141
- PPAR?/?: A master regulator of mesenchymal stem cell functions. Biochimie. 2017;136(): 55-58
- Important Role of CD11c+Dendtritic Cells in Inflammatory Arthritis Arthritis Rheumatol. 2017;69():
- NOVEL MECHANISM MEDIATED BY THE IL23/TH17 AXIS CONTRIBUTING TO AUTO-IMMUNE ARTHRITIS Ann Rheum Dis. 2017;76 1(): A6-A7
- IMPORTANT ROLE OF CD11C+DENDRITIC CELLS IN INFLAMMATORY ARTHRITIS Ann Rheum Dis. 2017;76 Suppl 2(): 492-492
- A role for 12/15-lipoxygenase-derived proresolving mediators in postoperative ileus: protectin DX-regulated neutrophil extravasation. J Leukoc Biol. 2016;99(2): 231-9
- PPAR?/? directs the therapeutic potential of mesenchymal stem cells in arthritis. Ann Rheum Dis. 2016;75(12): 2166-2174
- Novel Mechanism Mediated By the IL-23/Th17 Axis Contributing to Auto-Immune Arthritis Arthritis Rheumatol. 2016;68():
- IL-17/23 IN THE TRANSITION FROM AUTOIMMUNITY TO INFLAMMATION Clin Exp Rheumatol. 2016;34(4): 726-726
- From 3D Printed Bones to Arthritis Patients - Arthro-Haptic Experience Supporting Disease Awareness Arthritis Rheumatol. 2016;68():
- 12/15-Lipoxygenase-mediated enzymatic lipid oxidation regulates DC maturation and function. J Clin Invest. 2015;125(5): 1944-54
- Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages. Ann Rheum Dis. 2015;74(6): 1317-24
- Fc-gamma receptors are not involved in cartilage damage during experimental osteoarthritis. Osteoarthritis Cartilage. 2015;23(7): 1221-5
- Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss. Nat Commun. 2015;6(): 6651
- The Oxidative Burst Mediates Anti-Inflammatory Clearance of Dead Cells in a Mouse Model of SLE and Inflammatory Arthritis Arthritis Rheumatol. 2015;67 10(): -
- Important Role of CD11c+Dendritic Cells in Inflammatory Arthritis Arthritis Rheumatol. 2015;67 10(): -
- Loss of Phosphatase and Tensin Homolog in APCs Impedes Th17-Mediated Autoimmune Encephalomyelitis. J Immunol. 2015;195(6): 2560-70
- The oxidative burst mediates anti-inflammatory clearance of dead cells in a mouse model of Systemic lupus Erythematosus (SLE) and inflammatory arthritis Clin Exp Rheumatol. 2015;33 90(3): S9-S9
- NUCLEAR RECEPTOR NR4A1 AS A CHECKPOINT OF PHYSIOLOGICAL WOUND HEALING AND FIBROSIS Ann Rheum Dis. 2015;74 Suppl 2(): 584-584