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Routine Laboratory for rheumatic, immunological, infectious and allergological autoimmune diagnostics

Routine Laboratory

The rheumatological, immunological, infectious and allergological routine laboratory of the Department of Medicine 3 has been in existence for over 40 years and offers a broad spectrum of rheumatological and allergological autoimmune diagnostics.


  • Rheumatological and immunological antibody diagnostics including organ-related autoantibody diagnostics. Examples for the determination of rheumatism: Determination of rheumatoid factors, anti-CCP antibodies, anti-nuclear antibodies or anti-phospholipid antibodies
  • Cytokine determinations such as tumor necrosis factor, interleukin-1 or interleukin-6
  • Parameters of bone metabolism such as vitamin D, parathormone, C-telopeptide (CrossLaps) or osteocalcin

You will find a more detailed overview of our offer for autoimmune and bone metabolism diagnostics in our request form. The correct interpretation of the immunological laboratory findings is only possible in conjunction with the clinical symptoms. Our medical staff will be happy to advise you and discuss the findings.

Request form

For the clarification of immunodeficiencies we carry out various cellular immunological examinations.

Analysis of lymphocyte subpopulations in peripheral blood:

  • Routine Panel (CD3, CD4, CD8, B-cells, NK-cells)
  • other markers such as gamma-delta T cells or regulatory T cells on request

Analysis of lymphocyte subpopulations in bronchial lavage:

  • Routine panel (CD3, CD4, CD8)
  • on request further markers like CD1 and gamma-delta T-cells

Lymphocyte function analysis: lymphocyte proliferation, cytokine production and NK activity

The Routine Laboratory offers the following allergological diagnostics:

  • Early blossoming, grass, cereal and herb pollen and houseplants
  • Textiles, latex proteins, animal epithelia and animal serum proteins
  • Moulds, bacteria, house dust mites and storage mites
  • Insect proteins including toxic proteins
  • Drugs and occupational allergens
  • a variety of food allergens

Prof. Dr. H.-W. Baenkler at the Department of Medicine 3 has developed a completely new method for the in vitro diagnosis of analgesic intolerance: If there is a clinical suspicion of an analgesic or salicylate intolerance, it enables this suspected diagnosis to be confirmed or invalidated for the first time with the aid of a cellular blood test. By determining the release of prostaglandin and leukotriene from blood leukocytes in the presence and absence of analgesics, reaction patterns are defined that speak for or against analgesic intolerance.

Detailed information on this novel test procedure can be found at: