Dr. C. Schauer

Publications: Dr. rer. nat. C. Schauer

Liu L, Shan L, Wang H, Schauer C, Schoen J, Zhu L, Lu C, Wang Z, Xue Y, Wu H, Martin H: Neutrophil Extracellular Trap-Borne Elastase Prevents Inflammatory Relapse in Intercritical Gout. Arthritis Rheumatol. 2023;75(6): 1039-1047
Singh J, Boettcher M, Dölling M, Heuer A, Hohberger B, Leppkes M, Naschberger E, Schapher M, Schauer C, Schoen J, Stürzl M, Vitkov L, Wang H, Zlatar L, Schett GA, Pisetsky DS, Liu ML, Herrmann M, Knopf J: Moonlighting chromatin: when DNA escapes nuclear control. Cell Death Differ. 2023;30(4): 861-875
Leppkes M, Lindemann A, Gößwein S, Paulus S, Roth D, Hartung A, Liebing E, Zundler S, Gonzalez-Acera M, Patankar JV, Mascia F, Scheibe K, Hoffmann M, Uderhardt S, Schauer C, Foersch S, Neufert C, Vieth M, Schett G, Atreya R, Kühl AA, Bleich A, Becker C, Herrmann M, Neurath MF: Neutrophils prevent rectal bleeding in ulcerative colitis by peptidyl-arginine deiminase-4-dependent immunothrombosis. Gut. 2022;71(12): 2414-2429
Singh J, Herrmann I, Mahajan A, Schauer C, Shan X, Hartmann A, Rieker RJ, Evert K, Falkeis C, Naschberger E, von Stillfried S, Boor P, Muñoz LE, Schett G, Herrmann M, Knopf J: A Pleomorphic Puzzle: Heterogeneous Pulmonary Vascular Occlusions in Patients with COVID-19. Int J Mol Sci. 2022;23(23):
Schoen J, Euler M, Schauer C, Schett G, Herrmann M, Knopf J, Yaykasli KO: Neutrophils' Extracellular Trap Mechanisms: From Physiology to Pathology. Int J Mol Sci. 2022;23(21):
Dölling M, Eckstein M, Singh J, Schauer C, Schoen J, Shan X, Bozec A, Knopf J, Schett G, Muñoz LE, Herrmann M: Hypoxia Promotes Neutrophil Survival After Acute Myocardial Infarction. Front Immunol. 2022;13():
Vitkov L, Knopf J, Krunić J, Schauer C, Schoen J, Minnich B, Hannig M, Herrmann M: Periodontitis-Derived Dark-NETs in Severe Covid-19. Front Immunol. 2022;13():
Singh J, Shan X, Mahajan A, Herrmann M, Schauer C, Knopf J, Muñoz LE: Induction of Ocular Surface Inflammation and Collection of Involved Tissues. J Vis Exp. 2022;(186):
Ackermann M, Anders HJ, Bilyy R, Bowlin GL, Daniel C, De Lorenzo R, Egeblad M, Henneck T, Hidalgo A, Hoffmann M, Hohberger B, Kanthi Y, Kaplan MJ, Knight JS, Knopf J, Kolaczkowska E, Kubes P, Leppkes M, Mahajan A, Manfredi AA, Maueröder C, Maugeri N, Mitroulis I, Muñoz LE, Narasaraju T, Naschberger E, Neeli I, Ng LG, Radic MZ, Ritis K, Rovere-Querini P, Schapher M, Schauer C, Simon HU, Singh J, Skendros P, Stark K, Stürzl M, van der Vlag J, Vandenabeele P, Vitkov L, von Köckritz-Blickwede M, Yanginlar C, Yousefi S, Zarbock A, Schett G, Herrmann M: Patients with COVID-19: in the dark-NETs of neutrophils. Cell Death Differ. 2021;28(11): 3125-3139
Mahajan A, Hasíková L, Hampel U, Grüneboom A, Shan X, Herrmann I, Garreis F, Bock F, Knopf J, Singh J, Schauer C, Mahajan S, Leppkes M, Paulsen F, Schlötzer-Schrehardt U, Krenn V, Jünemann A, Hohberger B, Schett G, Herrmann M, Muñoz LE: Aggregated neutrophil extracellular traps occlude Meibomian glands during ocular surface inflammation. Ocul Surf. 2021;20(): 1-12
Yaykasli KO, Schauer C, Muñoz LE, Mahajan A, Knopf J, Schett G, Herrmann M: Neutrophil Extracellular Trap-Driven Occlusive Diseases. Cells. 2021;10(9):
Vitkov L, Muñoz LE, Schoen J, Knopf J, Schauer C, Minnich B, Herrmann M, Hannig M: Neutrophils Orchestrate the Periodontal Pocket. Front Immunol. 2021;12():
Vitkov L, Muñoz LE, Knopf J, Schauer C, Oberthaler H, Minnich B, Hannig M, Herrmann M: Connection between Periodontitis-Induced Low-Grade Endotoxemia and Systemic Diseases: Neutrophils as Protagonists and Targets. Int J Mol Sci. 2021;22(9):
Cossarizza A, Chang HD, Radbruch A, Abrignani S, Addo R, Akdis M, Andrä I, Andreata F, Annunziato F, Arranz E, Bacher P, Bari S, Barnaba V, Barros-Martins J, Baumjohann D, Beccaria CG, Bernardo D, Boardman DA, Borger J, Böttcher C, Brockmann L, Burns M, Busch DH, Cameron G, Cammarata I, Cassotta A, Chang Y, Chirdo FG, Christakou E, Čičin-Šain L, Cook L, Corbett AJ, Cornelis R, Cosmi L, Davey MS, De Biasi S, De Simone G, Del Zotto G, Delacher M, Di Rosa F, Santo JD, Diefenbach A, Dong J, Dörner T, Dress RJ, Dutertre CA, Eckle SBG, Eede P, Evrard M, Falk CS, Feuerer M, Fillatreau S, Fiz-Lopez A, Follo M, Foulds GA, Fröbel J, Gagliani N, Galletti G, Gangaev A, Garbi N, Garrote JA, Geginat J, Gherardin NA, Gibellini L, Ginhoux F, Godfrey DI, Gruarin P, Haftmann C, Hansmann L, Harpur CM, Hayday AC, Heine G, Hernández DC, Herrmann M, Hoelsken O, Huang Q, Huber S, Huber JE, Huehn J, Hundemer M, Hwang WYK, Iannacone M, Ivison SM, Jäck HM, Jani PK, Keller B, Kessler N, Ketelaars S, Knop L, Knopf J, Koay HF, Kobow K, Kriegsmann K, Kristyanto H, Krueger A, Kuehne JF, Kunze-Schumacher H, Kvistborg P, Kwok I, Latorre D, Lenz D, Levings MK, Lino AC, Liotta F, Long HM, Lugli E, MacDonald KN, Maggi L, Maini MK, Mair F, Manta C, Manz RA, Mashreghi MF, Mazzoni A, McCluskey J, Mei HE, Melchers F, Melzer S, Mielenz D, Monin L, Moretta L, Multhoff G, Muñoz LE, Muñoz-Ruiz M, Muscate F, Natalini A, Neumann K, Ng LG, Niedobitek A, Niemz J, Almeida LN, Notarbartolo S, Ostendorf L, Pallett LJ, Patel AA, Percin GI, Peruzzi G, Pinti M, Pockley AG, Pracht K, Prinz I, Pujol-Autonell I, Pulvirenti N, Quatrini L, Quinn KM, Radbruch H, Rhys H, Rodrigo MB, Romagnani C, Saggau C, Sakaguchi S, Sallusto F, Sanderink L, Sandrock I, Schauer C, Scheffold A, Scherer HU, Schiemann M, Schildberg FA, Schober K, Schoen J, Schuh W, Schüler T, Schulz AR, Schulz S, Schulze J, Simonetti S, Singh J, Sitnik KM, Stark R, Starossom S, Stehle C, Szelinski F, Tan L, Tarnok A, Tornack J, Tree TIM, van Beek JJP, van de Veen W, van Gisbergen K, Vasco C, Verheyden NA, von Borstel A, Ward-Hartstonge KA, Warnatz K, Waskow C, Wiedemann A, Wilharm A, Wing J, Wirz O, Wittner J, Yang JHM, Yang J: Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition). Eur J Immunol. 2021;51(12): 2708-3145
Hosari D, Hosari S, Mahajan A, Oreski L, Schoen J, Shan X, Singh J, Wang H, Yaykasli KO, Knopf J, Munoz LE, Schauer C, Herrmann M: NEUTROPHILS AND NETS AS ORCHESTRATORS OF INFLAMMATORY DISEASES Clin Exp Rheumatol. 2021;39(5): 1151-1152
Leppkes M, Knopf J, Naschberger E, Lindemann A, Singh J, Herrmann I, Stürzl M, Staats L, Mahajan A, Schauer C, Kremer AN, Völkl S, Amann K, Evert K, Falkeis C, Wehrfritz A, Rieker RJ, Hartmann A, Kremer AE, Neurath MF, Muñoz LE, Schett G, Herrmann M: Vascular occlusion by neutrophil extracellular traps in COVID-19. EBioMedicine. 2020;58():
Haskamp S, Bruns H, Hahn M, Hoffmann M, Gregor A, Löhr S, Hahn J, Schauer C, Ringer M, Flamann C, Frey B, Lesner A, Thiel CT, Ekici AB, von Hörsten S, Aßmann G, Riepe C, Euler M, Schäkel K, Philipp S, Prinz JC, Mößner R, Kersting F, Sticherling M, Sefiani A, Lyahyai J, Sondermann W, Oji V, Schulz P, Wilsmann-Theis D, Sticht H, Schett G, Reis A, Uebe S, Frey S, Hüffmeier U: Myeloperoxidase Modulates Inflammation in Generalized Pustular Psoriasis and Additional Rare Pustular Skin Diseases. Am J Hum Genet. 2020;107(3): 527-538
Schapher M, Koch M, Weidner D, Scholz M, Wirtz S, Mahajan A, Herrmann I, Singh J, Knopf J, Leppkes M, Schauer C, Grüneboom A, Alexiou C, Schett G, Iro H, Muñoz LE, Herrmann M: Neutrophil Extracellular Traps Promote the Development and Growth of Human Salivary Stones. Cells. 2020;9(9):
Vitkov L, Minnich B, Knopf J, Schauer C, Hannig M, Herrmann M: NETs Are Double-Edged Swords with the Potential to Aggravate or Resolve Periodontal Inflammation. Cells. 2020;9(12):
Hahn J, Schauer C, Czegley C, Kling L, Petru L, Schmid B, Weidner D, Reinwald C, Biermann MHC, Blunder S, Ernst J, Lesner A, Bäuerle T, Palmisano R, Christiansen S, Herrmann M, Bozec A, Gruber R, Schett G, Hoffmann MH: Aggregated neutrophil extracellular traps resolve inflammation by proteolysis of cytokines and chemokines and protection from antiproteases. FASEB J. 2019;33(1): 1401-1414
Boeltz S, Amini P, Anders HJ, Andrade F, Bilyy R, Chatfield S, Cichon I, Clancy DM, Desai J, Dumych T, Dwivedi N, Gordon RA, Hahn J, Hidalgo A, Hoffmann MH, Kaplan MJ, Knight JS, Kolaczkowska E, Kubes P, Leppkes M, Manfredi AA, Martin SJ, Maueröder C, Maugeri N, Mitroulis I, Munoz LE, Nakazawa D, Neeli I, Nizet V, Pieterse E, Radic MZ, Reinwald C, Ritis K, Rovere-Querini P, Santocki M, Schauer C, Schett G, Shlomchik MJ, Simon HU, Skendros P, Stojkov D, Vandenabeele P, Berghe TV, van der Vlag J, Vitkov L, von Köckritz-Blickwede M, Yousefi S, Zarbock A, Herrmann M: To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps. Cell Death Differ. 2019;26(3): 395-408
Mahajan A, Grüneboom A, Petru L, Podolska MJ, Kling L, Maueröder C, Dahms F, Christiansen S, Günter L, Krenn V, Jünemann A, Bock F, Schauer C, Schett G, Hohberger B, Herrmann M, Munoz LE: Frontline Science: Aggregated neutrophil extracellular traps prevent inflammation on the neutrophil-rich ocular surface. J Leukoc Biol. 2019;105(6): 1087-1098
Muñoz LE, Boeltz S, Bilyy R, Schauer C, Mahajan A, Widulin N, Grüneboom A, Herrmann I, Boada E, Rauh M, Krenn V, Biermann MHC, Podolska MJ, Hahn J, Knopf J, Maueröder C, Paryzhak S, Dumych T, Zhao Y, Neurath MF, Hoffmann MH, Fuchs TA, Leppkes M, Schett G, Herrmann M: Neutrophil Extracellular Traps Initiate Gallstone Formation. Immunity. 2019;51(3): 443-450.e4
Podolska MJ, Mahajan A, Hahn J, Knopf J, Maueroeder C, Petru L, Ullmann M, Schett G, Leppkes M, Herrmann M, Munoz LE, Schauer C: Treatment with DNases rescues hidden neutrophil elastase from aggregated NETs J Leukoc Biol. 2019;106(6): 1359-1366
Lutaty A, Soboh S, Schif-Zuck S, Zeituni-Timor O, Rostoker R, Podolska MJ, Schauer C, Herrmann M, Munoz LE, Ariel A: A 17-kDa Fragment of Lactoferrin Associates With the Termination of Inflammation and Peptides Within Promote Resolution Front Immunol. 2018;9():
Soboh S, Schif-Zuck S, Lutaty A, Zeituni-Timor O, Rostoker R, Podolska MJ, Munoz LE, Schauer C, Herrmann M, Ariel A: A 17 kDa fragment of lactoferrin associates with the termination of inflammation and peptides within promote resolution Eur J Clin Invest. 2018;48(): 77-77
Czegley C, Gillmann C, Schauer C, Seyler L, Reinwald C, Hahn M, Uder M, Jochmann K, Naschberger E, Stock M, Schett G, Bäuerle T, Hoffmann MH: A model of chronic enthesitis and new bone formation characterized by multimodal imaging. Dis Model Mech. 2018;11(9):
Reinwald C, Schauer C, Csepregi JZ, Kienhöfer D, Weidner D, Malissen M, Mocsai A, Schett G, Herrmann M, Hoffmann M: Erratum: Reply to "Neutrophils are not required for resolution of acute gouty arthritis in mice". Nat Med. 2017;23(4): 526
Grayson PC, Schauer C, Herrmann M, Kaplan MJ: Review: Neutrophils as Invigorated Targets in Rheumatic Diseases. Arthritis Rheumatol. 2016;68(9): 2071-82
Munoz LE, Bilyy R, Biermann MH, Kienhöfer D, Maueröder C, Hahn J, Brauner JM, Weidner D, Chen J, Scharin-Mehlmann M, Janko C, Friedrich RP, Mielenz D, Dumych T, Lootsik MD, Schauer C, Schett G, Hoffmann M, Zhao Y, Herrmann M: Nanoparticles size-dependently initiate self-limiting NETosis-driven inflammation. Proc Natl Acad Sci U S A. 2016;113(40): E5856-E5865
Pieterse E, Jeremic I, Czegley C, Weidner D, Biermann MH, Veissi S, Maueröder C, Schauer C, Bilyy R, Dumych T, Hoffmann M, Munoz LE, Bengtsson AA, Schett G, van der Vlag J, Herrmann M: Blood-borne phagocytes internalize urate microaggregates and prevent intravascular NETosis by urate crystals. Sci Rep. 2016;6(): 38229
Reinwald C, Schauer C, Csepregi JZ, Kienhöfer D, Weidner D, Malissen M, Mocsai A, Schett G, Herrmann M, Hoffmann M: Reply to "Neutrophils are not required for resolution of acute gouty arthritis in mice". Nat Med. 2016;22(12): 1384-1386
Desai J, Vr SK, Mulay SR, Konrad L, Romoli S, Schauer C, Herrmann M, Bilyy R, Müller S, Popper B, Nakazawa D, Weidenbusch M, Thomasova D, Krautwald S, Linkermann A, Anders HJ: PMA and crystal-induced neutrophil extracellular trap formation involves RIPK1-RIPK3-MLKL signaling. Eur J Immunol. 2016;46(1): 223-9
Maueröder C, Kienhöfer D, Hahn J, Schauer C, Manger B, Schett G, Herrmann M, Hoffmann MH: How neutrophil extracellular traps orchestrate the local immune response in gout. J Mol Med. 2015;93(7): 727-34
Schett G, Schauer C, Hoffmann M, Herrmann M: Why does the gout attack stop? A roadmap for the immune pathogenesis of gout. RMD Open. 2015;1(Suppl 1): e000046
Schauer C, Czegley C, Billyy R, Hahn J, Rech J, Munoz L, Schett G, Herrmann M, Hoffmann MH: THE OXIDATIVE BURST MEDIATES RESOLUTION OF INFLAMMATION AND BONE HOMEOSTASIS IN GOUT Ann Rheum Dis. 2015;74 Suppl 1(): A39-A39
Jeremic I, Schorn C, Munoz L, Terzic T, Schett G, Herrmann M: CHOLESTEROL CRYSTALS INDUCE NEUTROPHIL EXTRACELLULAR TRAPS FORMATION Ann Rheum Dis. 2014;73 Suppl 1(): A94-A94
Janko C, Filipovi? M, Munoz LE, Schorn C, Schett G, Ivanovi?-Burmazovi? I, Herrmann M: Redox Modulation of HMGB1-Related Signaling. Antioxid Redox Signal. 2014;20(7): 1075-85
Frischholz B, Wunderlich R, Rühle PF, Schorn C, Rödel F, Keilholz L, Fietkau R, Gaipl US, Frey B: Reduced secretion of the inflammatory cytokine IL-1? by stimulated peritoneal macrophages of radiosensitive Balb/c mice after exposure to 0.5 or 0.7 Gy of ionizing radiation. Autoimmunity. 2013;46(5): 323-8
Janko C, Pauthner M, Munoz L, Franz S, Schorn C, Sheriff A, Schett G, Herrmann M: COMPLEXES OF ANTI-CRP AUTOANTIBODIES AND CRP-OPSONISED APOPTOTIC CELL REMNANTS FORM A PRO-INFLAMMATORY PATHOGEN IN SYSTEMIC LUPUS ERYTHEMATOSUS Ann Rheum Dis. 2013;71 Suppl 3(): 526-526
Schorn C, Zhao Y, Janko C, Schett G, Herrmann M: TOPHUS FORMATION LIMITS NEUTROPHIL-INDUCED INFLAMMATION Ann Rheum Dis. 2013;71 Suppl 3(): 320-320
Chaurio R, Janko C, Schorn C, Maueröder C, Bilyy R, Gaipl U, Schett G, Berens C, Frey B, Munoz LE: UVB-irradiated apoptotic cells induce accelerated growth of co-implanted viable tumor cells in immune competent mice. Autoimmunity. 2013;46(5): 317-22
Janko C, Dürr S, Munoz LE, Lyer S, Chaurio R, Tietze R, Löhneysen Sv, Schorn C, Herrmann M, Alexiou C: Magnetic drug targeting reduces the chemotherapeutic burden on circulating leukocytes. Int J Mol Sci. 2013;14(4): 7341-55
Sarter K, Janko C, André S, Munoz LE, Schorn C, Winkler S, Rech J, Kaltner H, Lorenz HM, Schiller M, Andreoli L, Manfredi AA, Isenberg DA, Schett G, Herrmann M, Gabius HJ: Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus. Glycobiology. 2013;23(1): 12-22
Janko C, Jeremic I, Biermann M, Chaurio R, Schorn C, Munoz LE, Herrmann M: Cooperative binding of Annexin A5 to phosphatidylserine on apoptotic cell membranes. Phys Biol. 2013;10(6): 065006
Schorn C, Munoz L, Hoffmann M, Schett G, Herrmann M: Tophusformation regulates Inflammation in Gouty Arthritis Internist (Berl). 2013;54 Suppl 1(): 62-62
Schorn C, Janko C, Latzko M, Chaurio R, Schett G, Herrmann M: Monosodium urate crystals induce extracellular DNA traps in neutrophils, eosinophils, and basophils but not in mononuclear cells. Front Immunol. 2012;3(): 277
Lödermann B, Wunderlich R, Frey S, Schorn C, Stangl S, Rödel F, Keilholz L, Fietkau R, Gaipl US, Frey B: Low dose ionising radiation leads to a NF-?B dependent decreased secretion of active IL-1? by activated macrophages with a discontinuous dose-dependency. Int J Radiat Biol. 2012;88(10): 727-34
Herman S, Kny A, Schorn C, Pfatschbacher J, Niederreiter B, Herrmann M, Holmdahl R, Steiner G, Hoffmann MH: Cell death and cytokine production induced by autoimmunogenic hydrocarbon oils. Autoimmunity. 2012;45(8): 602-11
Janko C, André S, Munoz LE, Briand JP, Schorn C, Winkler S, Schiller M, Andreoli L, Manfredi AA, Isenberg DA, Schett G, Gabius HJ, Müller S, Herrmann M: Autoantibodies against galectin-2 peptides as biomarkers for the antiphospholipid syndrome. Lupus. 2012;21(7): 781-3
Pauthner M, Janko C, Baum W, Schorn C, Dobias H, Moder A, Schett G, Herrmann M: RADON THERAPY AMELIORATES DISEASE PROGRESSION AND PROLONGS SURVIVAL IN TNF alpha TG MICE Ann Rheum Dis. 2012;71 Suppl 1():
Cui BB, Tan CY, Schorn C, Tang HH, Liu Y, Zhao Y: Neutrophil extracellular traps in sterile inflammation: the story after dying? Autoimmunity. 2012;45(8): 593-6
Schorn C, Janko C, Krenn V, Zhao Y, Munoz LE, Schett G, Herrmann M: Bonding the foe - NETting neutrophils immobilize the pro-inflammatory monosodium urate crystals. Front Immunol. 2012;3(): 376
Schorn C, Frey B, Lauber K, Janko C, Strysio M, Keppeler H, Gaipl US, Voll RE, Springer E, Munoz LE, Schett G, Herrmann M: Sodium overload and water influx activate the NALP3 inflammasome. J Biol Chem. 2011;286(1): 35-41
Harre U, Derer A, Schorn C, Schett G, Herrmann M: T cells as key players for bone destruction in gouty arthritis? Arthritis Res Ther. 2011;13(6): 135
Janko C, Schorn C, Munoz LE, Rauh M, Schett G, Herrmann M: CRP DISCRIMINATES PRIMARY FROM SECONDARY NECROSIS Ann Rheum Dis. 2011;70 Suppl 2():
Schorn C, Strysio M, Janko C, Springer E, Munoz LE, Schett G, Herrmann M: MSU, THE ADJUVANS OF DYING CELLS ACTIVATES THE NALP3 INFLAMMASOME BY SODIUM OVERLOAD Ann Rheum Dis. 2011;70 Suppl 2():
Munoz LE, Janko C, Schulze C, Schorn C, Sarter K, Schett G, Herrmann M: Autoimmunity and chronic inflammation - two clearance-related steps in the etiopathogenesis of SLE. Autoimmun Rev. 2010;10(1): 38-42
Schorn C, Strysio M, Janko C, Munoz LE, Schett G, Herrmann M: The uptake by blood-borne phagocytes of monosodium urate is dependent on heat-labile serum factor(s) and divalent cations. Autoimmunity. 2010;43(3): 236-8
Janko C, Schorn C, Weidner D, Sarter K, Chaurio R, Sheriff A, Schett G, Munoz LE: Treatment with DNAse I fosters binding to nec PBMC of CRP. Autoimmunity. 2009;42(4): 286-8
Schorn C, Janko C, Munoz L, Schulze C, Strysio M, Schett G, Herrmann M: Sodium and potassium urate crystals differ in their inflammatory potential. Autoimmunity. 2009;42(4): 314-6
Janko C, Schorn C, Grossmayer G, Gaipl U, Herrmann M, Munoz L: Anti-DSDNA autoantibodies mediate inflammatory clearance of nuclear fragments in whole blood in patients with SLE Clin Exp Rheumatol. 2008;26 Suppl. (1): P20 -

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Publications: Dr. rer. nat. C. Schauer

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