Prof. Dr. G. Schett

Publications: Prof. Dr. med. univ. G. Schett

Faghihi-Kashani S, Yoshida A, Bozan F, Zanframundo G, Rozza D, Loganathan A, Dourado E, Sambataro G, Bauer-Ventura I, Bae SS, Lim D, Rivero-Gallegos D, Yamano Y, Selva-O'Callaghan A, Mammen AL, Scirè CA, Montecucco C, Oddis CV, Fiorentino D, Bonella F, Miller FW, Lundberg IE, Schmidt J, Rojas-Serrano J, Hudson M, Kuwana M, González-Gay MA, McHugh N, Corte TJ, Doyle TJ, Werth VP, Gupta L, Perez Roman DI, Bianchessi LM, Devarasetti PK, Shinjo SK, Luppi F, Cavazzana I, Moghadam-Kia S, Fornaro M, Volkmann ER, Piga M, Loarce-Martos J, De Luca G, Knitza J, Wolff-Cecchi V, Sebastiani M, Schiffenbauer A, Rider LG, Campanilho-Marques R, Marts L, Bravi E, Gunawardena H, Aggarwal R, Cavagna L, Classification Criteria for Anti‐Synthetase Syndrome Project participating investigators , Anuja A, Sambataro D, Colaci M, Vancheri C, Mejia M, Rivera Matias PA, Bottazzi F, Alpini C, Rajasekhar L, Agarwal V, De Souza FHC, Miossi R, Pozzi MR, Faverio P, Franco G, Dei G, Franceschini F, Lacomis D, Iannone F, Girolamo F, Trallero-Araguás E, Gil-Vila A, Villar A, Charles-Schoeman C, Bukiri H, Murru C, Cauli A, Bachiller-Corral J, Dagna L, Campochiaro C, Distler J, Schett G, Florenzano M, Reyes F, Amato A, Dellaripa P, Saavedra S, Vergara K, Manfredi A, Vacchi C, Melo T, Gandiga P, Amratia D, Arrigoni E, Kaneko Y, Triantafyllias K, Mandel A, Castañeda S, Vicente-Rabaneda EF, Landon-Cardinal O, Alberti ML, Caro F, Greco Merino MG, Rua-Figueroa I, Fiehn C, Bauhammer J, Molad Y, Klein O, Govoni M, Nakashima R, Alpsoy E, Meyer A, Giannini M, Chinoy H, Lilleker J, Gallay L, Cottin V, Dieudè P, Campagne J, Saraiva AP, Conticini E, Sebastiani G, Nuno L, Scarpato S, Schiopu E, Sainaghi PP, Jovani V, Barsotti S, Umezawa N, Needham M, Cagnotto G, Danieli MG, Tomietto P, Gomez NP, Limonta M, Barausse G, Kondo Y, Ghetie D, Tamirou F, Basharat P, Tomaras S, Voll RE, Andersson H, Barrio JM, Schneider M, Parronchi P, Notarnicola A, Cifrian J: Clinical Characteristics of Anti-Synthetase Syndrome: Analysis From the Classification Criteria for Anti-Synthetase Syndrome Project. Arthritis Rheumatol. 2025;77(4): 477-489
Mougiakakos D, Sengupta R, Gold R, Schroers R, Haghikia A, Lorente M, Pendleton M, Register A, Heesen C, Kröger N, Schett G, Mackensen A, Podoll A, Gutman J, Furie R, Bayer R, Distler JHW, Dietrich S, Krönke G, Bullinger L, Walker K: Successful generation of fully human, second generation, anti-CD19 CAR T cells for clinical use in patients with diverse autoimmune disorders. Cytotherapy. 2025;27(2): 236-246
Auth J, Müller F, Völkl S, Bayerl N, Distler JHW, Tur C, Raimondo MG, Chenguiti Fakhouri S, Atzinger A, Coppers B, Eckstein M, Liphardt AM, Bäuerle T, Tascilar K, Aigner M, Kretschmann S, Wirsching A, Taubmann J, Hagen M, Györfi AH, Kharboutli S, Krickau T, Dees C, Spörl S, Rothe T, Harrer T, Bozec A, Grieshaber-Bouyer R, Fuchs F, Kuwert T, Berking C, Horch RE, Uder M, Mackensen A, Schett G, Bergmann C: CD19-targeting CAR T-cell therapy in patients with diffuse systemic sclerosis: a case series. Lancet Rheumatol.. 2025;7(2): e83-e93
Zhu L, Wang Y, Shan L, Xue Y, Schett G, Herrmann M, Liu L: Colchicine inhibits monosodium urate crystal-mediated inflammation by influencing F-actin formation. Biochim Biophys Acta Mol Basis Dis. 2025;1871(3):
Keret S, Kaly L, Schett G, Bergmann C, Feldman E, Zuckerman T, Yehudai-Ofir D, Shouval A, Awisat A, Rosner I, Rozenbaum M, Boulman N, Sawaed A, Hardak E, Henes J, Slobodin G, Rimar D: Neutrophil-to-lymphocyte ratio as a biomarker for clinical response after autologous haematopoietic stem cell transplantation in systemic sclerosis. Rheumatology (Oxford). 2025;64(5): 3160-3165
Meng X, Asadi-Asadabad S, Cao S, Song R, Lin Z, Safhi M, Qin Y, Tcheumi Tactoum E, Taudte V, Ekici A, Mielenz D, Wirtz S, Schett G, Bozec A: Metabolic rewiring controlled by HIF-1α tunes IgA-producing B-cell differentiation and intestinal inflammation. Cell Mol Immunol. 2025;22(1): 54-67
Bergmann C, Chenguiti Fakhouri S, Trinh-Minh T, Filla T, Rius Rigau A, Ekici AB, Merlevede B, Hallenberger L, Zhu H, Dees C, Matei AE, Auth J, Györfi AH, Zhou X, Rauber S, Bozec A, Dickel N, Liang C, Kunz M, Schett G, Distler JHW: Mutual Amplification of GLI2/Hedgehog and Transcription Factor JUN/AP-1 Signaling in Fibroblasts in Systemic Sclerosis: Potential Implications for Combined Therapies. Arthritis Rheumatol. 2025;77(1): 92-98
Mougiakakos D, Meyer E, Schett G: CAR T cells in autoimmunity: game changer or stepping stone? Blood. 2025;145(17): 1841-1849
Seese FK, Roscher P, Coppers B, Greenfield J, Grahammer M, Kuhn S, Gupta L, Schett G, Knitza J, Liphardt AM: Toward digitally supported self-assessment of patients with idiopathic inflammatory myopathies. Arthritis Res Ther. 2025;27(1):
Coppers B, Heinrich S, Tascilar K, Phutane U, Kleyer A, Simon D, Bräunig J, Penner J, Vossiek M, Schönau V, Bayat S, Schett G, Leyendecker S, Liphardt AM: Sensor-assessed grasping time as a biomarker of functional impairment in rheumatoid arthritis. Sci Rep. 2025;15(1):
Pfeuffer N, Hartmann F, Grahammer M, Simon D, Schuster L, Kuhn S, Krönke G, Schett G, Knitza J, Kleyer A: Early detection of rheumatoid arthritis through patient empowerment by tailored digital monitoring and education: a feasibility study. Rheumatol Int. 2025;45(2):
Falck D, Sokolova MV, Koeleman CAM, Irumva V, Kirchner P, Schulz SR, Schmidt KG, Harrer T, Ekici AB, Spriewald B, Schett G, Wuhrer M, Herrmann M, Steffen U: IgA displays site- and subclass-specific glycoform differences despite equal glycoenzyme expression. Cell Commun Signal. 2025;23(1):
Junt T, Calzascia T, Traggiai E, da Costa AN, Gergely P, Schett G, Dörner T, Siegel RM: Defining immune reset: achieving sustained remission in autoimmune diseases. Nat Rev Immunol. 2025;():
Albrecht A, Taubmann J, Minopoulou I, Hatscher L, Kleinert S, Mühlensiepen F, Welcker M, Leipe J, Schulz N, Klemm P, Hueber A, Schett G, Kuhn S, Labinsky H, Knitza J: Real-World-Evidence of Digital Health Applications (DiGAs) in Rheumatology: Insights from the DiGAReal Registry. Rheumatol Ther. 2025;12(2): 267-282
Taubmann J, Mueller F, Mutlu MY, Voelkl S, Aigner M, Bozec A, Mackensen A, Grieshaber-Bouyer R, Schett G: Correction to CD19 Chimeric Antigen Receptor T Cell Treatment: Unraveling the Role of B Cells in Systemic Lupus Erythematosus. Arthritis Rheumatol. 2025;77(3):
Deane KD, Holers VM, Emery P, Mankia K, El-Gabalawy H, Sparks JA, Costenbader KH, Schett G, van der Helm-van Mil A, van Schaardenburg D, Thomas R, Cope AP: Therapeutic interception in individuals at risk of rheumatoid arthritis to prevent clinically impactful disease. Ann Rheum Dis. 2025;84(1): 14-28
Györfi AH, Filla T, Polzin A, Tascilar K, Buch M, Tröbs M, Matei AE, Airo P, Balbir-Gurman A, Kuwert F, Mihai C, Kabala A, Graßhoff H, Callaghan J, Isomura Y, Mansour J, Spierings J, Tennoe AH, Selvi E, Riccieri V, Hoffmann-Vold AM, Bergmann C, Schett G, Hunzelmann N, van Laar JM, Saketkoo LA, Kuwana M, Siegert E, Riemekasten G, Distler O, du Four T, Smith V, Truchetet ME, Distler JHW, EUSTAR collaborators: Evaluation of Systemic Sclerosis Primary Heart Involvement and Chronic Heart Failure in the European Scleroderma Trials and Research Cohort. J Am Heart Assoc. 2025;14(5):
Minopoulou I, Fagni F, Atzinger A, Albach F, Schett G, Krönke G, Kleyer A, Simon D: Unconventional Imaging Methods in Psoriatic Arthritis. Curr Rheumatol Rep. 2025;27(1):
Bartenschlager S, Cavallaro A, Pogarell T, Uder M, Chaudry O, Schett G, Engelke K: Impact of intravenous CT contrast agents on internal calibration techniques to determine trabecular BMD of the lumbar spine. Eur J Radiol. 2025;183():
Jia Y, Li R, Li Y, Kachler K, Meng X, Gießl A, Qin Y, Zhang F, Liu N, Andreev D, Schett G, Bozec A: Melanoma bone metastasis-induced osteocyte ferroptosis via the HIF1α-HMOX1 axis. Bone Res. 2025;13(1):
Li Y, Li S, Zhao X, Sheng J, Xue L, Schett G, Shi C, Hu B, Wang X, Chen Z: Fourth-generation chimeric antigen receptor T-cell therapy is tolerable and efficacious in treatment-resistant rheumatoid arthritis. Cell Res. 2025;35(3): 220-223
Dingfelder J, Taubmann J, von Heydebrand F, Aigner M, Bergmann C, Knitza J, Park S, Cheng JK, Van Blarcom T, Schett G, Mackensen A, Lutzny-Geier G: Exploring CAR T-Cell Dynamics: Balancing Potent Cytotoxicity and Controlled Inflammation in CAR T-Cells Derived from Systemic Sclerosis and Myositis Patients. Int J Mol Sci. 2025;26(2):
Mill L, Aust O, Ackermann JA, Burger P, Pascual M, Palumbo-Zerr K, Krönke G, Uderhardt S, Schett G, Clemen CS, Holtzhausen C, Jabari S, Schröder R, Maier A, Grüneboom A: Deep learning-based image analysis in muscle histopathology using photo-realistic synthetic data. Commun Med (Lond). 2025;5(1):
Yalcin Mutlu M, Kleyer A, Kroenke G, Fagni F, Temiz SA, Meder C, Dietrich P, Orlemann T, Mößner J, Schoenau V, Bohr D, Schuster L, Hartmann F, Minopoulou I, Leppkes M, Ramming A, Pachowsky ML, Schuch F, Ronneberger M, Kleinert S, Hueber AJ, Manger K, Manger B, Atreya R, Berking C, Sticherling M, Neurath MF, Schett G, Simon D, Tascilar K: Paucity of viral infection symptoms in patients with immune-mediated inflammatory diseases. BMJ Open. 2025;15(1):
Fagni F, Motta F, Schett G, Selmi C: Difficult-to-Treat Psoriatic Arthritis: A Conceptual Approach. Arthritis Rheumatol. 2024;76(5): 670-674
Taubmann J, Müller F, Yalcin Mutlu M, Völkl S, Aigner M, Bozec A, Mackensen A, Grieshaber-Bouyer R, Schett G: CD19 Chimeric Antigen Receptor T Cell Treatment: Unraveling the Role of B Cells in Systemic Lupus Erythematosus. Arthritis Rheumatol. 2024;76(4): 497-504
Greco R, Alexander T, Del Papa N, Müller F, Saccardi R, Sanchez-Guijo F, Schett G, Sharrack B, Snowden JA, Tarte K, Onida F, Sánchez-Ortega I, Burman J, Castilla Llorente C, Cervera R, Ciceri F, Doria A, Henes J, Lindsay J, Mackensen A, Muraro PA, Ricart E, Rovira M, Zuckerman T, Yakoub-Agha I, Farge D: Innovative cellular therapies for autoimmune diseases: expert-based position statement and clinical practice recommendations from the EBMT practice harmonization and guidelines committee. EClinicalMedicine. 2024;69():
Cao S, Li Y, Song R, Meng X, Fuchs M, Liang C, Kachler K, Meng X, Wen J, Schlötzer-Schrehardt U, Taudte V, Gessner A, Kunz M, Schleicher U, Zaiss MM, Kastbom A, Chen X, Schett G, Bozec A: L-arginine metabolism inhibits arthritis and inflammatory bone loss. Ann Rheum Dis. 2024;83(1): 72-87
Andreev D, Kachler K, Liu M, Chen Z, Krishnacoumar B, Ringer M, Frey S, Krönke G, Voehringer D, Schett G, Bozec A: Eosinophils preserve bone homeostasis by inhibiting excessive osteoclast formation and activity via eosinophil peroxidase. Nat Commun. 2024;15(1):
Rech J, Tascilar K, Hagen M, Kleyer A, Manger B, Schoenau V, Hueber AJ, Kleinert S, Baraliakos X, Braun J, Kiltz U, Fleck M, Rubbert-Roth A, Kofler DM, Behrens F, Feuchtenberger M, Zaenker M, Voll R, Venhoff N, Thiel J, Glaser C, Feist E, Burmester GR, Karberg K, Strunk J, Cañete JD, Senolt L, Filkova M, Naredo E, Largo R, Krönke G, D'Agostino MA, Østergaard M, Schett G: Abatacept inhibits inflammation and onset of rheumatoid arthritis in individuals at high risk (ARIAA): a randomised, international, multicentre, double-blind, placebo-controlled trial. Lancet. 2024;403(10429): 850-859
Noversa de Sousa R, Tascilar K, Corte G, Atzinger A, Minopoulou I, Ohrndorf S, Waldner M, Schmidkonz C, Kuwert T, Knieling F, Kleyer A, Ramming A, Schett G, Simon D, Fagni F: Metabolic and molecular imaging in inflammatory arthritis. RMD Open. 2024;10(1):
Schälter F, Azizov V, Frech M, Dürholz K, Schmid E, Hendel A, Sarfati I, Maeda Y, Sokolova M, Miyagawa I, Focke K, Sarter K, van Baarsen LGM, Krautwald S, Schett G, Zaiss MM: CCL19-Positive Lymph Node Stromal Cells Govern the Onset of Inflammatory Arthritis via Tropomyosin Receptor Kinase. Arthritis Rheumatol. 2024;76(6): 857-868
Siebert S, Coates LC, Schett G, Raychaudhuri SP, Chen W, Gao S, Seridi L, Chakravarty SD, Shawi M, Lavie F, Sharaf M, Zimmermann M, Kollmeier AP, Xu XL, Rahman P, Mease PJ, Deodhar A: Modulation of Interleukin-23 Signaling With Guselkumab in Biologic-Naive Patients Versus Tumor Necrosis Factor Inhibitor-Inadequate Responders With Active Psoriatic Arthritis. Arthritis Rheumatol. 2024;76(6): 894-904
Boy K, von Rohr S, May S, Kuhn S, Schett G, Labinsky H, Knitza J, Muehlensiepen F: Pre-assessment of patients with suspected axial spondyloarthritis combining student-led clinics and telemedicine: a qualitative study. Rheumatol Int. 2024;44(4): 663-673
Pachowsky ML, Söllner S, Gelse K, Sambale J, Nagel AM, Schett G, Saake M, Uder M, Roemer FW, Heiss R: Primary anterior cruciate ligament repair-morphological and quantitative assessment by 7-T MRI and clinical outcome after 1.5 years. Eur Radiol. 2024;34(8): 5007-5015
Zlatar L, Knopf J, Singh J, Wang H, Muñoz-Becerra M, Herrmann I, Chukwuanukwu RC, Eckstein M, Eichhorn P, Rieker RJ, Naschberger E, Burkovski A, Krenn V, Bilyy R, Butova T, Liskina I, Kalabukha I, Khmel O, Boettcher M, Schett G, Butov D, Tkachenko A, Herrmann M: Neutrophil extracellular traps characterize caseating granulomas. Cell Death Dis. 2024;15(7):
Bartenschlager S, Cavallaro A, Pogarell T, Chaudry O, Uder M, Khosla S, Schett G, Engelke K: Response to the editor of JBMR regarding the letter related to "Opportunistic screening with CT: comparison of phantomless BMD calibration methods". J Bone Miner Res. 2024;39(6): 804-805
Schlereth M, Mutlu MY, Utz J, Bayat S, Heimann T, Qiu J, Ehring C, Liu C, Uder M, Kleyer A, Simon D, Roemer F, Schett G, Breininger K, Fagni F: Deep learning-based classification of erosion, synovitis and osteitis in hand MRI of patients with inflammatory arthritis. RMD Open. 2024;10(2):
Knitza J, Tascilar K, Fuchs F, Mohn J, Kuhn S, Bohr D, Muehlensiepen F, Bergmann C, Labinsky H, Morf H, Araujo E, Englbrecht M, Vorbrüggen W, von der Decken CB, Kleinert S, Ramming A, Distler JHW, Bartz-Bazzanella P, Vuillerme N, Schett G, Welcker M, Hueber A: Diagnostic Accuracy of a Mobile AI-Based Symptom Checker and a Web-Based Self-Referral Tool in Rheumatology: Multicenter Randomized Controlled Trial. J Med Internet Res. 2024;26():
Knitza J, Hasanaj R, Beyer J, Ganzer F, Slagman A, Bolanaki M, Napierala H, Schmieding ML, Al-Zaher N, Orlemann T, Muehlensiepen F, Greenfield J, Vuillerme N, Kuhn S, Schett G, Achenbach S, Dechant K: Comparison of Two Symptom Checkers (Ada and Symptoma) in the Emergency Department: Randomized, Crossover, Head-to-Head, Double-Blinded Study. J Med Internet Res. 2024;26():
Raulien N, Friedrich K, Strobel S, Raps S, Hecker F, Pierer M, Schilling E, Lainka E, Kallinich T, Baumann S, Fritz-Wallace K, Rolle-Kampczyk U, von Bergen M, Aigner A, Ewe A, Schett G, Cross M, Rossol M, Wagner U: Glucose-oxygen deprivation constrains HMGCR function and Rac1 prenylation and activates the NLRP3 inflammasome in human monocytes. Sci Signal. 2024;17(845):
Coates LC, Schett G, Wang C, Weiss PF: Unmet Needs in Spondyloarthritis: Pathogenesis, Clinical Trial Design, and Nonpharmacologic Therapy. J Rheumatol. 2024;51(12): 1254-1258
Schett G, June CH: CAR T cells in autoimmune disease: On the road to remission. Immunity. 2024;57(12): 2705-2709
Schett G, Müller F, Taubmann J, Mackensen A, Wang W, Furie RA, Gold R, Haghikia A, Merkel PA, Caricchio R, D'Agostino MA, Locatelli F, June CH, Mougiakakos D: Advancements and challenges in CAR T cell therapy in autoimmune diseases. Nat Rev Rheumatol. 2024;20(9): 531-544
Boy K, May S, Labinsky H, Morf H, Heinze M, Leipe J, Kuhn S, Schett G, Knitza J, Muehlensiepen F: Correction: Back on track- digital health applications to treat back pain of rheumatic patients? Results of a qualitative interview study. Rheumatol Int. 2024;44(12): 2989-2990
Boy K, May S, Labinsky H, Morf H, Heinze M, Leipe J, Kuhn S, Schett G, Knitza J, Muehlensiepen F: Back on track - digital health applications to treat back pain of rheumatic patients? Results of a qualitative interview study. Rheumatol Int. 2024;44(12): 2977-2987
Yaykasli KO, van Schie KA, Toes REM, Wuhrer M, Koeleman CAM, Bila G, Negrych N, Schett G, Knopf J, Herrmann M, Bilyy R: Neutrophil Depletion Changes the N-Glycosylation Pattern of IgG in Experimental Murine Sepsis. Int J Mol Sci. 2024;25(12):
Kachler K, Andreev D, Thapa S, Royzman D, Gießl A, Karuppusamy S, Llerins Perez M, Liu M, Hofmann J, Gessner A, Meng X, Rauber S, Steinkasserer A, Fromm M, Schett G, Bozec A: Acod1-mediated inhibition of aerobic glycolysis suppresses osteoclast differentiation and attenuates bone erosion in arthritis. Ann Rheum Dis. 2024;83(12): 1691-1706
Yalcin-Mutlu M, Icacan OC, Yildirim F, Temiz SA, Fagni F, Schett G, Tascilar K, Minopoulou I, Burul G, Bes C: IL-1 Inhibitors in the Treatment of Familial Mediterranean Fever: Treatment Indications and Clinical Features in a Large Real-World Cohort. J Clin Med. 2024;13(12):
Corte G, Atzinger A, Temiz SA, Noversa de Sousa R, Mutlu MY, Schoenau V, Raimondo MG, Kleyer A, Kuwert T, Ramming A, Simon D, Sticherling M, Schmidkonz C, Schett G, Fagni F: Anatomical pattern of entheseal and synovial fibroblast activation in patients with psoriasis and its risk of developing psoriatic arthritis. RMD Open. 2024;10(2):
Siebert S, Schett G, Raychaudhuri SP, Guma M, Chen W, Gao S, Chakravarty SD, Lavie F, Rahman P: Correlation of changes in inflammatory and collagen biomarkers with durable guselkumab efficacy through 2 years in participants with active psoriatic arthritis: results from a phase III randomized controlled trial. Ther Adv Musculoskelet Dis. 2024;16():
Alsuliman T, Marjanovic Z, Rimar D, Tarte K, Avcin T, Hagen M, Schett G, Farge D: Harnessing the potential of CAR-T cell in lupus treatment: From theory to practice. Autoimmun Rev. 2024;23(12):
Krishnacoumar B, Stenzel M, Garibagaoglu H, Omata Y, Sworn RL, Hofmann T, Ipseiz N, Czubala MA, Steffen U, Maccataio A, Stoll C, Böhm C, Herrmann M, Uderhardt S, Jenkins RH, Taylor PR, Grüneboom A, Zaiss MM, Schett G, Krönke G, Scholtysek C: Caspase-8 promotes scramblase-mediated phosphatidylserine exposure and fusion of osteoclast precursors. Bone Res. 2024;12(1):
Chenguiti Fakhouri S, Zhu H, Li YN, Ronicke M, Rigau AR, Dees C, Konstantinidis L, Schmid R, Matei AE, Eckstein M, Geppert C, Ludolph I, Kreuter A, Sticherling M, Berking C, Horch RE, Schett G, Distler JHW, Bergmann C: Disturbed spatial WNT activation - a potential driver of the reticularized skin phenotype in Systemic Sclerosis (SSc). Arthritis Rheumatol. 2024;():
Haghikia A, Hegelmaier T, Wolleschak D, Böttcher M, Pappa V, Motte J, Borie D, Gold R, Feist E, Schett G, Mougiakakos D: Clinical efficacy and autoantibody seroconversion with CD19-CAR T cell therapy in a patient with rheumatoid arthritis and coexisting myasthenia gravis. Ann Rheum Dis. 2024;83(11): 1597-1598
Schett G, Mackensen A, Mougiakakos D: CAR T-cell perspectives in lupus - Authors' reply. Lancet. 2024;404(10450): 336-337
Blaskowitz PPVA, Liphardt AM, Bouzas C, Coppers B, Petit P, Vuillerme N, Bundle V, Rudolf S, Knitza J, Raimondo MG, Labinsky H, Hatscher L, Wirsching A, Bohr D, Araujo E, Ramming A, Ramming A, Schett G, Morf H: Impact of the digital health application ViViRA on spinal mobility, physical function, quality of life and pain perception in spondyloarthritides patients: a randomized controlled trial. Arthritis Res Ther. 2024;26(1):
Rius Rigau A, Liang M, Devakumar V, Neelagar R, Matei AE, Györfi AH, Bergmann C, Filla T, Fedorchenko V, Schett G, Distler JHW, Li YN: Imaging mass cytometry-based characterisation of fibroblast subsets and their cellular niches in systemic sclerosis. Ann Rheum Dis. 2024;():
Abir AH, Weckwerth L, Wilhelm A, Thomas J, Reichardt CM, Munoz L, Völkl S, Appelt U, Mroz M, Niesner R, Hauser A, Sophie Fischer R, Pracht K, Jäck HM, Schett G, Krönke G, Mielenz D: Metabolic profiling of single cells by exploiting NADH and FAD fluorescence via flow cytometry. Mol Metab. 2024;87():
Neurath L, Sticherling M, Schett G, Fagni F: Targeting cytokines in psoriatic arthritis. Cytokine Growth Factor Rev. 2024;78(): 1-13
Salehi F, Lopera Gonzalez LI, Bayat S, Kleyer A, Zanca D, Brost A, Schett G, Eskofier BM: Machine Learning Prediction of Treatment Response to Biological Disease-Modifying Antirheumatic Drugs in Rheumatoid Arthritis. J Clin Med. 2024;13(13):
Regierer AC, Kiefer D, Schett G, Krause A, Weiß A, Sewerin P, Strangfeld A: No difference in clinical parameters and drug retention in PsA patients receiving b/tsDMARD monotherapy versus combination with methotrexate: data from the RABBIT-SpA registry. RMD Open. 2024;10(3):
Grube L, Petit P, Vuillerme N, Nitschke M, Nwosu OB, Knitza J, Krusche M, Seifer AK, Eskofier BM, Schett G, Morf H: Complementary App-Based Yoga Home Exercise Therapy for Patients With Axial Spondyloarthritis: Usability Study. JMIR Form Res. 2024;8():
Bugatti S, Schett G: Prevention of seronegative rheumatoid arthritis: an entity of its own. Lancet Rheumatol.. 2024;6(12): e812-e813
Hagen M, Müller F, Wirsching A, Kharboutli S, Spörl S, Aigner M, Völkl S, Köhler B, Dörfler A, Grieshaber-Bouyer R, Mackensen A, Schett G: Treatment of CNS systemic lupus erythematosus with CD19 CAR T cells. Lancet. 2024;404(10468): 2158-2160
Schett G, Nagy G, Krönke G, Mielenz D: B-cell depletion in autoimmune diseases. Ann Rheum Dis. 2024;83(11): 1409-1420
Singh J, Zlatar L, Muñoz-Becerra M, Lochnit G, Herrmann I, Pfister F, Janko C, Knopf J, Leppkes M, Schoen J, Muñoz LE, Schett G, Herrmann M, Schauer C, Mahajan A: Calpain-1 weakens the nuclear envelope and promotes the release of neutrophil extracellular traps. Cell Commun Signal. 2024;22(1):
Taylor PC, Schett G, Huizinga TW, Wang Q, Ibrahim F, Zhou B, Liva SG, Shaik JSB, Xiong Y, Leu JH, Panchakshari RA, Loza MJ, Ma K, Dhatt H, Rojo Cella R, Karyekar CS, Cuff CA, Gao S, Fei K: Nipocalimab, an anti-FcRn monoclonal antibody, in participants with moderate to severe active rheumatoid arthritis and inadequate response or intolerance to anti-TNF therapy: results from the phase 2a IRIS-RA study. RMD Open. 2024;10(2):
Schuster L, Henes J, Diener M, Mühlensiepen F, Andreica I, Hueber A, Schett G, Knitza J: [Measurement of disease-related knowledge of patients with axial spondyloarthritis-Development and application of the G-ASKQ7 questionnaire]. Z Rheumatol. 2024;():
Hagen M, Wirsching A, Bohr D, Taubmann J, Mueller F, Mackensen A, Grieshaber-Bouyer R, Schett G: CAR-T-Zell-Therapie in der Rheumatologie - Was wissen wir bisher? Z Rheumatol. 2024;():
Hagen M, Bucci L, Böltz S, Nöthling DM, Rothe T, Anoshkin K, Raimondo MG, Tur C, Wirsching A, Wacker J, Düsing C, Distler JHW, Kuwert T, Bozec A, Ramming A, Schett G, Grieshaber-Bouyer R: BCMA-Targeted T-Cell-Engager Therapy for Autoimmune Disease. N Engl J Med. 2024;391(9): 867-869
Labinsky H, May S, Boy K, von Rohr S, Grahammer M, Kuhn S, Rojas-Restrepo J, Vogt E, Heinze M, Schett G, Muehlensiepen F, Knitza J: Evaluation of a hybrid telehealth care pathway for patients with axial spondyloarthritis including self-sampling at home: results of a longitudinal proof-of-concept mixed-methods study (TeleSpactive). Rheumatol Int. 2024;44(6): 1133-1142
Rech J, Schett G, Tufan A, Kuemmerle-Deschner JB, Özen S, Tascilar K, Geck L, Krickau T, Cohen E, Welzel T, Kuehn M, Vetterli M: Patient Experiences and Challenges in the Management of Autoinflammatory Diseases-Data from the International FMF &amp; AID Global Association Survey. J Clin Med. 2024;13(5):
Wilhelm A, Chambers D, Müller F, Bozec A, Grieshaber-Bouyer R, Winkler T, Mougiakakos D, Mackensen A, Schett G, Krönke G: Selective CAR T cell-mediated B cell depletion suppresses IFN signature in SLE. JCI Insight. 2024;9(12):
Rauber S, Mohammadian H, Schmidkonz C, Atzinger A, Soare A, Treutlein C, Kemble S, Mahony CB, Geisthoff M, Angeli MR, Raimondo MG, Xu C, Yang KT, Lu L, Labinsky H, Saad MSA, Gwellem CA, Chang J, Huang K, Kampylafka E, Knitza J, Bilyy R, Distler JHW, Hanlon MM, Fearon U, Veale DJ, Roemer FW, Bäuerle T, Maric HM, Maschauer S, Ekici AB, Buckley CD, Croft AP, Kuwert T, Prante O, Cañete JD, Schett G, Ramming A: CD200+ fibroblasts form a pro-resolving mesenchymal network in arthritis. Nat Immunol. 2024;25(4): 682-692
Trinh-Minh T, Chen CW, Tran Manh C, Li YN, Zhu H, Zhou X, Chakraborty D, Zhang Y, Rauber S, Dees C, Lin NY, Kah D, Gerum R, Bergmann C, Kreuter A, Reuter C, Groeber-Becker F, Eckes B, Distler O, Fabry B, Ramming A, Schambony A, Schett G, Distler JH: Noncanonical WNT5A controls the activation of latent TGF-β to drive fibroblast activation and tissue fibrosis. J Clin Invest. 2024;134(10):
Dingfelder J, Aigner M, Taubmann J, Minopoulou I, Park S, Kaplan CD, Cheng JK, Van Blarcom T, Schett G, Mackensen A, Lutzny-Geier G: Fully Human Anti-CD19 CAR T Cells Derived from Systemic Lupus Erythematosus Patients Exhibit Cytotoxicity with Reduced Inflammatory Cytokine Production. Transplant Cell Ther. 2024;30(6): 582.e1-582.e10
Lyu P, Wen J, Zhang W, Liu N, Stolzer I, Gießl A, Jia Y, Mauro D, Zhang F, Ciccia F, Soulat D, Günther C, Schett G, Bozec A: Expression of HIF1α in intestinal epithelium restricts arthritis inflammation by inhibiting RIPK3-induced cell death machinery. Ann Rheum Dis. 2024;83(8): 984-997
Manger B, Schett G: Bessel's disease-the first report of an IgG4-related disorder. Z Rheumatol. 2024;83(8): 661-663
Gossec L, Kerschbaumer A, Ferreira RJO, Aletaha D, Baraliakos X, Bertheussen H, Boehncke WH, Esbensen BA, McInnes IB, McGonagle D, Winthrop KL, Balanescu A, Balint PV, Burmester GR, Cañete JD, Claudepierre P, Eder L, Hetland ML, Iagnocco A, Kristensen LE, Lories R, Queiro R, Mauro D, Marzo-Ortega H, Mease PJ, Nash P, Wagenaar W, Savage L, Schett G, Shoop-Worrall SJW, Tanaka Y, Van den Bosch FE, van der Helm-van Mil A, Zabotti A, van der Heijde D, Smolen JS: EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2023 update. Ann Rheum Dis. 2024;83(6): 706-719
Zabotti A, Fagni F, Gossec L, Giovannini I, Sticherling M, Tullio A, Baraliakos X, De Marco G, De Vita S, Errichetti E, Quartuccio L, Silvagni E, Smolen JS, Tinazzi I, Watad A, Schett G, McGonagle DG, Simon D: Risk of developing psoriatic arthritis in psoriasis cohorts with arthralgia: exploring the subclinical psoriatic arthritis stage. RMD Open. 2024;10(2):
Jia Y, Zhang F, Meng X, Andreev D, Lyu P, Zhang W, Lai C, Schett G, Bozec A: Osteocytes support bone metastasis of melanoma cells by CXCL5. Cancer Lett. 2024;590():
Rius Rigau A, Li YN, Matei AE, Györfi AH, Bruch PM, Koziel S, Devakumar V, Gabrielli A, Kreuter A, Wang J, Dietrich S, Schett G, Distler JHW, Liang M: Characterization of Vascular Niche in Systemic Sclerosis by Spatial Proteomics. Circ Res. 2024;134(7): 875-891
Liang M, Dickel N, Györfi AH, SafakTümerdem B, Li YN, Rigau AR, Liang C, Hong X, Shen L, Matei AE, Trinh-Minh T, Tran-Manh C, Zhou X, Zehender A, Kreuter A, Zou H, Schett G, Kunz M, Distler JHW: Attenuation of fibroblast activation and fibrosis by adropin in systemic sclerosis. Sci Transl Med. 2024;16(740):
Auger JP, Zimmermann M, Faas M, Stifel U, Chambers D, Krishnacoumar B, Taudte RV, Grund C, Erdmann G, Scholtysek C, Uderhardt S, Ben Brahim O, Pascual Maté M, Stoll C, Böttcher M, Palumbo-Zerr K, Mangan MSJ, Dzamukova M, Kieler M, Hofmann M, Blüml S, Schabbauer G, Mougiakakos D, Sonnewald U, Hartmann F, Simon D, Kleyer A, Grüneboom A, Finotto S, Latz E, Hofmann J, Schett G, Tuckermann J, Krönke G: Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids. Nature. 2024;629(8010): 184-192
Fagni F, Tascilar K, Noversa de Sousa R, Bayat S, Sollfrank L, Kleyer A, Sticherling M, Regensburger AP, Knieling F, Neurath MF, Schett G, Waldner M, Simon D: Unveiling Metabolic Similarities of Entheses in Patients with Psoriasis and Psoriatic Arthritis Using Noninvasive In Vivo Molecular Imaging: Results From a Cross-sectional Exploratory Study. Arthritis Rheumatol. 2024;76(9): 1387-1396
Bucci L, Hagen M, Rothe T, Raimondo MG, Fagni F, Tur C, Wirsching A, Wacker J, Wilhelm A, Auger JP, Pachowsky M, Eckstein M, Alivernini S, Zoli A, Krönke G, Uderhardt S, Bozec A, D'Agostino MA, Schett G, Grieshaber-Bouyer R: Bispecific T cell engager therapy for refractory rheumatoid arthritis. Nat Med. 2024;30(6): 1593-1601
Reichardt CM, Muñoz-Becerra M, Rius Rigau A, Rückert M, Fietkau R, Schett G, Gaipl US, Frey B, Muñoz LE: Neutrophils seeking new neighbors: radiotherapy affects the cellular framework and the spatial organization in a murine breast cancer model. Cancer Immunol Immunother. 2024;73(4):
Pedersen RS, Thorlacius-Ussing J, Raimondo MG, Langholm LL, Schett G, Ramming A, Karsdal M, Willumsen N: Fibroblast Activation Protein (FAP)-Mediated Cleavage of Type III Collagen Reveals Serum Biomarker Potential in Non-Small Cell Lung Cancer and Spondyloarthritis. Biomedicines. 2024;12(3):
Haghikia A, Schett G, Mougiakakos D: B cell-targeting chimeric antigen receptor T cells as an emerging therapy in neuroimmunological diseases. Lancet Neurol. 2024;23(6): 615-624
Krickau T, Naumann-Bartsch N, Aigner M, Kharboutli S, Kretschmann S, Spoerl S, Vasova I, Völkl S, Woelfle J, Mackensen A, Schett G, Metzler M, Müller F: CAR T-cell therapy rescues adolescent with rapidly progressive lupus nephritis from haemodialysis. Lancet. 2024;403(10437): 1627-1630
Rahman P, McInnes IB, Deodhar A, Schett G, Mease PJ, Shawi M, Cua DJ, Sherlock JP, Kollmeier AP, Xu XL, Sheng S, Ritchlin CT, McGonagle D: Association between enthesitis/dactylitis resolution and patient-reported outcomes in guselkumab-treated patients with psoriatic arthritis. Clin Rheumatol. 2024;43(5): 1591-1604
Müller F, Mackensen A, Schett G: CAR T-Cell Therapy in Autoimmune Disease. Reply. N Engl J Med. 2024;390(17): 1631-1632
Manger B, Schett G: Magnesium Disorders. N Engl J Med. 2024;391(7): 668-669
Müller F, Taubmann J, Bucci L, Wilhelm A, Bergmann C, Völkl S, Aigner M, Rothe T, Minopoulou I, Tur C, Knitza J, Kharboutli S, Kretschmann S, Vasova I, Spoerl S, Reimann H, Munoz L, Gerlach RG, Schäfer S, Grieshaber-Bouyer R, Korganow AS, Farge-Bancel D, Mougiakakos D, Bozec A, Winkler T, Krönke G, Mackensen A, Schett G: CD19 CAR T-Cell Therapy in Autoimmune Disease - A Case Series with Follow-up. N Engl J Med. 2024;390(8): 687-700
Kachler K, Andreev D, Schett G, Bozec A: Inhibition of aerobic glycolysis viaAcod1 suppresses osteoclast differentiation and reduces bone erosion in arthritis J Bone Miner Res. 2024;39 Suppl 1(): 219-219
Atzinger A, Huang Y, Tascilar K, Bayerl N, Distler J, Staudt K, Kartalczik H, Bruni C, Distler O, Hoffmann-Vold AM, Baeuerle T, Prenner A, Putz F, Breininger K, Kuwert T, Kainz B, Schett G, Bergmann C: FAPI-PET/CT as a Predictor of Accelerated Lung Function Deterioration in Systemic Sclerosis Related Interstitial Lung Disease (ILD): Preliminaryinterim Analysis from a Confirmatory Risk Factor Study Arthritis Rheumatol. 2024;76 Suppl 9(): 3445-3448
Auth J, Selvaraju MK, Mueller F, Gupta P, Ekici A, Tur C, Raimondo MG, Distler J, Dees C, Chenguiti S, Hagen M, Wirsching A, Taubmann J, Kharboutli S, Spoerl S, Aigner M, Kretschmann S, Vasova I, MAckensen A, Schett G, Bergmann C: First Analyses of Transcriptomic Changes in the Skin of SSc Patients upon CD19-targeting CAR T Cell Therapy Arthritis Rheumatol. 2024;76 Suppl 9(): 1644-1646
Tur C, Eckstein M, Velden J, Rauber S, Bergmann C, Auth J, Bucci L, Corte G, Hagen M, Wirsching A, Grieshaber-Bouyer R, Reis P, Kittan N, Wacker J, Rius Rigau A, Ramming A, D'Agostino MA, Hartmann A, Müller F, Mackensen A, Bozec A, Schett G, Raimondo MG: CD19-CAR T-cell therapy induces deep tissue depletion of B cells. Ann Rheum Dis. 2024;():
Pennington S, Zhou R, Brady J, Wundervald B, Parnell A, Duffy C, Perryman R, Waddington J, McHugh N, Jadon D, Simon D, Fagni F, Schett G, Morton F, Najm A, Siebert S, Coates L, FitzGerald O: Multi-centre Validation of a Serum Protein Biomarker Signature (RAPsA Dx), Which Discriminates Psoriatic Arthritis (PsA) from Rheumatoid Arthritis (RA) Arthritis Rheumatol. 2024;76 Suppl 9(): 5349-5350

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Publications: Prof. Dr. med. univ. G. Schett

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