Prof. Dr. G. Schett

Publikationen: Prof. Dr. med. univ. G. Schett

Garantziotis P, Beretta L, Lindblom J, Moysidou GS, Nikolopoulos D, Grieshaber-Bouyer R, Hagen M, Bergmann C, Wirsching A, Bozec A, PRECISESADS Clinical Consortium , Schneider M, Barturen G, Bertsias G, Boumpas DT, Alarcón-Riquelme ME, Mackensen A, Schett G, Parodis I:Differential molecular signatures in response to CD19-CAR T cell therapy compared with conventional pharmacotherapy in systemic lupus erythematosus.Ann Rheum Dis. 2026;85(1): 153-163
Freitag M, Kolb P, Falcone V, Claus M, Schröder P, Andreeva I, Rodon L, Ewald M, Deicher FS, Stütz AN, Distler JHW, Blank N, Grieshaber-Bouyer R, Muñoz LE, Lorenz HM, Schett G, Merkt W:Fcγ-receptor-activation by circulating immune complexes in systemic autoimmune diseases and its reduction by CD19-CAR T cell therapy.Rheumatology (Oxford). 2026;65(3):
Hong X, Xiao Y, Qi H, Zhu S, Filla T, Györfi AH, Li YN, Xu M, Zhi L, Trinh-Minh T, Dees C, Schett G, Distler JHW, Matei AE:Linezolid-mediated Prevention of Fibroblast Activation and Tissue Fibrosis via Mitochondrial Translation Inhibition.Arthritis Rheumatol. 2026;78(4): 914-927
Marzo-Ortega H, McInnes IB, Sharaf M, Zabotti A, Rampakakis E, McGonagle D, Abogamal A, Richette P, Schett G:Impact of dactylitis and enthesitis resolution on disease control in guselkumab-treated psoriatic arthritis patients with TNFi-IR: COSMOS post hoc analysis.Rheumatology (Oxford). 2026;65(1):
Raimondo MG, Mohammadian H, Rauber S, Alivernini S, Fedorchenko V, Rigau AR, Angeli MR, Fagni F, Corte G, Tascilar K, Labinsky H, Ramming AM, Roemer F, Rech J, Braeuer L, D'Agostino MA, Schett G, Pachowsky M, Kleyer A, Ramming A:Entheseal tissue signature in response to IL-17A inhibition in psoriatic arthritis: results from the EBIO entheseal biopsy study.Ann Rheum Dis. 2026;85(2): 285-296
Heidinger M, Lang C, Ferrari J, Krebs S, Sykora M, Kleyhons R, Resch H, Karisik A, Dejakum B, Mölgg K, Granna J, Boehme C, Willeit P, Knoflach M, Schett G, Kiechl S, Lang W:The risk of femoral fracture is increased in patients with ischemic stroke and transient ischemic attack-a population-based observational secondary analysis of the Austrian stroke cohort.Int J Stroke. 2026;21(2): 275-283
Tur C, Eckstein M, Rauber S, Schett G, Bozec A, Raimondo MG:Reply to Correspondence on: 'Effects of different B-cell-depleting strategies on the lymphatic tissue'.Ann Rheum Dis. 2026;85(1): e1-e2
Garantziotis P, Auth J, Schett G, Bergmann C:CAR T-cell therapy in systemic sclerosis: the next frontier in immune modulation.Curr Opin Rheumatol. 2026;38(1): 60-68
Wang Q, Xiao ZX, Zheng X, Wang G, Yang L, Shi L, Xiang N, Wang X, Zha GF, Schett G, Chen Z:In Vivo CD19 CAR T-Cell Therapy for Refractory Systemic Lupus Erythematosus.N Engl J Med. 2025;393(15): 1542-1544
Schlereth M, de Sousa RN, Corte G, Tur C, Minopoulou I, Mutlu MY, Temiz A, Bayat S, Simon D, Schett G, Kleyer A, Breininger K, Fagni F:DEVELOPMENT OFA DEEP LEARNING-BASED TOOL FOR THE AUTOMATED GRADING OF SYNOVITIS AND CLASSIFICATION OF ARTHRITIS USING ULTRASOUND IMAGINGAnn Rheum Dis. 2025;84 Suppl 1():
Yalcin Mutlu M, Kleyer A, Kroenke G, Fagni F, Temiz SA, Meder C, Dietrich P, Orlemann T, Mößner J, Schoenau V, Bohr D, Schuster L, Hartmann F, Minopoulou I, Leppkes M, Ramming A, Pachowsky ML, Schuch F, Ronneberger M, Kleinert S, Hueber AJ, Manger K, Manger B, Atreya R, Berking C, Sticherling M, Neurath MF, Schett G, Simon D, Tascilar K:Paucity of viral infection symptoms in patients with immune-mediated inflammatory diseases.BMJ Open. 2025;15(1):
Albrecht A, Taubmann J, Minopoulou I, Hatscher L, Kleinert S, Mühlensiepen F, Welcker M, Leipe J, Schulz N, Klemm P, Hueber A, Schett G, Kuhn S, Labinsky H, Knitza J:Real-World-Evidence of Digital Health Applications (DiGAs) in Rheumatology: Insights from the DiGAReal Registry.Rheumatol Ther. 2025;12(2): 267-282
Taubmann J, Böltz S, Hagen M, Wirsching A, Müller F, Völkl S, Kharboutli S, Spörl S, Garantziotis P, Aigner M, Grieshaber-Bouyer R, Mackensen A, Schett G:[Long-term follow up of efficiency and safety of CD19-CAR T-cell treatment of systemic lupus erythematosus].Z Rheumatol. 2025;84(8): 612-620
Ueberall L, Mohammadian H, Demmler R, Ariza Y, Tripal P, Anchang CG, Weber S, Angeli MR, Raimondo MG, Chang J, Huang K, Distler JHW, Distler O, Rauber S, Schett G, Ramming A, Ramming AM:Matrix stiffness regulates profibrotic fibroblast differentiation and fibrotic niche activation in systemic sclerosis.Ann Rheum Dis. 2025;84(11): 1865-1876
Coppers B, Bartanus V, Heinrich S, Bayat S, Kleyer A, Minopoulou I, Simon D, Corte G, Fagni F, Schoenau V, Schett G, Leyendecker S, Liphardt AM:BIOMECHANICAL INVESTIGATION OF IMPAIRMENTS IN PALM ARCH MOBILITY IN RHEUMATOID AND PSORIATIC ARTHRITIS PATIENTSAnn Rheum Dis. 2025;84 Suppl 1():
Noethling DM, Bucci L, Rothe T, Anoshkin K, Hagen M, Wirsching A, Taubmann J, Garantziotis P, Voelkl S, Mueller F, Mackensen A, Schett G, Grieshaber-Bouyer R:B CELL RECONSTITUTION IN SLE PATIENTS AFTER CAR-T CELL THERAPY IS MARKED BY A NAÏVE PHENOTYPE AND REDUCTION OF EXTRAFOLLICULAR IMMUNE RESPONSESAnn Rheum Dis. 2025;84 Suppl 1():
Pesch G, Piseddu I, Gaertig J, Kramer N, Kramer R, Schulz TU, Zwiebel M, Ledderose S, Retzlaff J, Eckstein M, Schett G, Kammerbauer C, Schmitt C, Kumbrink J, Erdmann M, Kruis W, Dougan M, Mayerle J, French LE, Vera J, Nordmann TM, Mann M, Klauschen F, Anz D, Heinzerling L:Deep Immune Phenotyping Reveals Distinct Immunopathogenesis in Checkpoint Inhibitor-Induced Colitis Compared with Ulcerative Colitis.Cancer Immunol Res. 2025;13(7): 1053-1069
Hess A, Tascilar K, Schenker HM, Konerth L, Schönau V, Sergeeva M, Kreitz S, Prade J, Strobelt S, Selvakumar M, Kleyer A, Englbrecht M, Hueber AJ, Zaiss MM, Feist E, Burmester GR, Voll RE, Finzel S, Baerwald C, Rösch J, Behrens F, Koehm M, da Silva JAP, Damjanov N, Dörfler A, Schett G, Rech J:Disease-associated brain activation predicts clinical response to TNF inhibition in rheumatoid arthritis (PreCePra): a randomised, multicentre, double-blind, placebo-controlled phase 3 study.Lancet Rheumatol.. 2025;7(8): e565-e575
Taubmann J, Mueller F, Mutlu MY, Voelkl S, Aigner M, Bozec A, Mackensen A, Grieshaber-Bouyer R, Schett G:Correction to CD19 Chimeric Antigen Receptor T Cell Treatment: Unraveling the Role of B Cells in Systemic Lupus Erythematosus.Arthritis Rheumatol. 2025;77(3):
Coppers B, Heinrich S, Tascilar K, Phutane U, Kleyer A, Simon D, Bräunig J, Penner J, Vossiek M, Schönau V, Bayat S, Schett G, Leyendecker S, Liphardt AM:Sensor-assessed grasping time as a biomarker of functional impairment in rheumatoid arthritis.Sci Rep. 2025;15(1):
Atzinger A, Tascilar K, Kleyer A, Hueber AJ, Schmidkonz C, Kuwert T, Beck M, Fagni F, Corte G, Ramming A, Schett G, Bayat S:Synovial fibroblast activation occurs before the onset of rheumatoid arthritis and influences the risk of developing disease.RMD Open. 2025;11(4):
Bucci L, Boeltz S, Hagen M, Noethling DM, Rothe T, Tur C, Wirsching A, Auth J, Wacker J, Eckstein M, Alivernini S, Bozec A, Bergmann C, DAgostino MA, Raimondo MG, Schett G, Grieshaber-Bouyer R:SAFETY AND EFFICACY OFT CELL ENGAGER THERAPY IN PATIENTS WITH REFRACTORY AUTOIMMUNE DISEASEAnn Rheum Dis. 2025;84 Suppl 1():
Rizzo C, Coronel L, De Lorenzis E, Rubortone P, Möller I, Miguel Perez M, Tur C, Raimondo MG, Belmonte B, Cancila V, Ramming A, Schett G, Lizzio MM, Alivernini S, Guggino G, D'Agostino MA:Minimally invasive ultrasound-guided biopsy of the common extensor tendon enthesis: a cadaveric study to standardise the technique.RMD Open. 2025;11(2):
Stuetz A, De Luca G, Matei AE, Li YN, Batani V, Filla T, Rigau AR, Tuemerdem BS, Bruni DC, Eckstein M, Schett G, Basso C, Distle J, Matucci-Cerinic M, Gyoerfi AH:SPATIAL PROTEOMIC-BASED PHENOTYPING OF FIBROBLAST SUBPOPULATIONS AND THEIR MICROENVIRONMENT IN SYSTEMIC SCLEROSIS PRIMARY HEART INVOLVEMENTAnn Rheum Dis. 2025;84 Suppl 1():
Deane KD, Holers VM, Emery P, Mankia K, El-Gabalawy H, Sparks JA, Costenbader KH, Schett G, van der Helm-van Mil A, van Schaardenburg D, Thomas R, Cope AP:Therapeutic interception in individuals at risk of rheumatoid arthritis to prevent clinically impactful disease.Ann Rheum Dis. 2025;84(1): 14-28
Ramiro S, Schett G, Marzo-Ortega H, Schmidt WA:The Impact of IL-17A Inhibition in Rheumatic and Musculoskeletal Diseases: Current Insights and Future Prospects.Rheumatol Ther. 2025;12(3): 435-451
Witte T, Minopoulou I, Drzeniek NM, Torgutalp M, Sabat R, Casteleyn V, Albach F, Fagni F, Schett G, Zabotti A, Krönke G, McGonagle D, Köhm M, Behrens F, Kleyer A, Simon D:Advances in precision medicine in imaging and therapeutic strategies for psoriatic disease.Autoimmun Rev. 2025;24(8):
Bucci L, Rothe T, Anoshkin K, Noethling DM, Goetz AK, Eckstein M, Raimondo MG, Schett G, Grieshaber-Bouyer R:EFFECTS OFT CELL ENGAGERS TREATMENT ON B ANDT CELLS IN AUTOIMMUNE DISEASEAnn Rheum Dis. 2025;84 Suppl 1(): 365-366
Dreiner M, Godonou ET, Mündermann A, Tascilar K, Schett G, Zaucke F, Liphardt AM, Niehoff A:Immobilization by 21-days of bed rest causes changes in biomarkers of cartilage homeostasis in healthy individuals.Osteoarthr Cartil Open. 2025;7(2):
Temiz A, Schuster L, Mutlu MY, Tascilar K, Bayat S, Rech J, Hueber A, Kleyer A, Simon D, Schett G, Fagni F:SECUKINUMAB DEMONSTRATES HIGH LONG-TERM EFFICACY, DRUG SURVIVAL, AND OSTEOPROTECTIVE EFFECTS IN PSORIATIC ARTHRITIS AND PSORIASIS: 48-MONTH FOLLOW-UP OF THE PSARTROS STUDYAnn Rheum Dis. 2025;84 Suppl 1():
Tur C, Eckstein M, Velden J, Rauber S, Bergmann C, Auth J, Bucci L, Corte G, Hagen M, Wirsching A, Grieshaber-Bouyer R, Reis P, Kittan N, Wacker J, Rius Rigau A, Ramming A, D'Agostino MA, Hartmann A, Müller F, Mackensen A, Bozec A, Schett G, Raimondo MG:CD19-CAR T-cell therapy induces deep tissue depletion of B cells.Ann Rheum Dis. 2025;84(1): 106-114
Pelzl R, Benintende G, Gsottberger F, Scholz JK, Ruebner M, Yao H, Wendland K, Rejeski K, Altmann H, Petkovic S, Mellenthin L, Kübel S, Schmiedeberg M, Klein P, Petrera A, Baur R, Eckstein S, Hoepffner-Grundy S, Röllig C, Subklewe M, Huebner H, Schett G, Mackensen A, Laurenti L, Graw F, Völkl S, Nganou-Makamdop K, Müller F:Large B-cell lymphoma imprints a dysfunctional immune phenotype that persists years after treatment.Blood. 2025;146(11): 1300-1313
Faghihi-Kashani S, Yoshida A, Bozan F, Zanframundo G, Rozza D, Loganathan A, Dourado E, Sambataro G, Bauer-Ventura I, Bae SS, Lim D, Rivero-Gallegos D, Yamano Y, Selva-O'Callaghan A, Mammen AL, Scirè CA, Montecucco C, Oddis CV, Fiorentino D, Bonella F, Miller FW, Lundberg IE, Schmidt J, Rojas-Serrano J, Hudson M, Kuwana M, González-Gay MA, McHugh N, Corte TJ, Doyle TJ, Werth VP, Gupta L, Perez Roman DI, Bianchessi LM, Devarasetti PK, Shinjo SK, Luppi F, Cavazzana I, Moghadam-Kia S, Fornaro M, Volkmann ER, Piga M, Loarce-Martos J, De Luca G, Knitza J, Wolff-Cecchi V, Sebastiani M, Schiffenbauer A, Rider LG, Campanilho-Marques R, Marts L, Bravi E, Gunawardena H, Aggarwal R, Cavagna L, Classification Criteria for Anti‐Synthetase Syndrome Project participating investigators , Anuja A, Sambataro D, Colaci M, Vancheri C, Mejia M, Rivera Matias PA, Bottazzi F, Alpini C, Rajasekhar L, Agarwal V, De Souza FHC, Miossi R, Pozzi MR, Faverio P, Franco G, Dei G, Franceschini F, Lacomis D, Iannone F, Girolamo F, Trallero-Araguás E, Gil-Vila A, Villar A, Charles-Schoeman C, Bukiri H, Murru C, Cauli A, Bachiller-Corral J, Dagna L, Campochiaro C, Distler J, Schett G, Florenzano M, Reyes F, Amato A, Dellaripa P, Saavedra S, Vergara K, Manfredi A, Vacchi C, Melo T, Gandiga P, Amratia D, Arrigoni E, Kaneko Y, Triantafyllias K, Mandel A, Castañeda S, Vicente-Rabaneda EF, Landon-Cardinal O, Alberti ML, Caro F, Greco Merino MG, Rua-Figueroa I, Fiehn C, Bauhammer J, Molad Y, Klein O, Govoni M, Nakashima R, Alpsoy E, Meyer A, Giannini M, Chinoy H, Lilleker J, Gallay L, Cottin V, Dieudè P, Campagne J, Saraiva AP, Conticini E, Sebastiani G, Nuno L, Scarpato S, Schiopu E, Sainaghi PP, Jovani V, Barsotti S, Umezawa N, Needham M, Cagnotto G, Danieli MG, Tomietto P, Gomez NP, Limonta M, Barausse G, Kondo Y, Ghetie D, Tamirou F, Basharat P, Tomaras S, Voll RE, Andersson H, Barrio JM, Schneider M, Parronchi P, Notarnicola A, Cifrian J:Clinical Characteristics of Anti-Synthetase Syndrome: Analysis From the Classification Criteria for Anti-Synthetase Syndrome Project.Arthritis Rheumatol. 2025;77(4): 477-489
Salehi F, Zarifi S, Bayat S, Habibpour M, Asemanrafat A, Kleyer A, Schett G, Fritsch-Stork R, Eskofier BM:Predicting Disease Activity Score in Rheumatoid Arthritis Patients Treated with Biologic Disease-Modifying Antirheumatic Drugs Using Machine Learning ModelsTechnologies. 2025;13(8):
Dand N, Stuart PE, Bowes J, Ellinghaus D, Nititham J, Saklatvala JR, Teder-Laving M, Thomas LF, Traks T, Uebe S, Assmann G, Baudry D, Behrens F, Billi AC, Brown MA, Burkhardt H, Capon F, Chung R, Curtis CJ, Duckworth M, Ellinghaus E, FitzGerald O, Gerdes S, Griffiths CEM, Gulliver S, Helliwell PS, Ho P, Hoffmann P, Holmen OL, Huang ZM, Hveem K, Jadon D, Köhm M, Kraus C, Lamacchia C, Lee SH, Ma F, Mahil SK, McHugh N, McManus R, Modalsli EH, Nissen MJ, Nöthen M, Oji V, Oksenberg JR, Patrick MT, Perez White BE, Ramming A, Rech J, Rosen C, Sarkar MK, Schett G, Schmidt B, Tejasvi T, Traupe H, Voorhees JJ, Wacker EM, Warren RB, Wasikowski R, Weidinger S, Wen X, Zhang Z, BSTOP study group , Estonian Biobank research team , Barton A, Chandran V, Esko T, Foerster J, Franke A, Gladman DD, Gudjonsson JE, Gulliver W, Hüffmeier U, Kingo K, Kõks S, Liao W, Løset M, Mägi R, Nair RP, Rahman P, Reis A, Smith CH, Di Meglio P, Barker JN, Tsoi LC, Simpson MA, Elder JT, Burden AD, Smith CH, Brown SJ, Dand N, Mahil SK, McAteer H, Schofield J, Siebert S, Metspalu A, Milani L, Nelis M:GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets.Nat Commun. 2025;16(1):
Bergmann C, Huang S, Auth J, Wirsching A, Hagen M, Kartalczik HN, Grieshaber-Bouyer R, Mueller F, Mackensen A, Schett G, Khanna D:TRAJECTORIES OF THE EUSTAR AI, ACR CRISS AND REVISED CRISS UPON CD19.CARTTREATMENT IN PATIENTS WITH DIFFUSE CUTANEOUS SYSTEMIC SCLEROSISAnn Rheum Dis. 2025;84 Suppl 1():
Minopoulou I, Wilhelm A, Albach FN, Kleyer A, Wiebe E, Fleischmann A, Frick M, Damm F, Borie D, Casteleyn V, Biesen R, Doerner T, Alexander T, Zernicke J, Hinkelmann L, Phitak E, Drzeniek NM, Movassaghi K, Huetter-Kroenke ML, Schrezenmeier E, Schreiber A, Schneider U, Schett G, Bullinger L, Kroenke G, Penack O, Simon D:EFFECT OF ANTI-CD19 CART CELLTHERAPY IN THE BONE MARROW OF PATIENTS WITH SYSTEMIC AUTOIMMUNE DISEASESAnn Rheum Dis. 2025;84 Suppl 1():
Jakobi S, Boy K, Wagner M, May S, Temiz A, Liphardt AM, Araujo E, Carmona L, Knevel R, Schett G, Knitza J, Muehlensiepen F, Morf H:Rheumatic? A diagnostic decision support tool for individuals suspecting rheumatic diseases: Mixed-methods usability and acceptability study.BMC Rheumatol. 2025;9(1):
Tragl S, Manger E, Niemiec L, Coppers B, Bayat S, Kleyer A, Simon D, Tascilar K, Rech J, Schett G, Hueber A, Liphardt AM:BONE MORPHOLOGY IS RELATED WITH HAND FUNCTION IN PATIENTS WITH RHEUMATOID ARTHRITISAnn Rheum Dis. 2025;84 Suppl 1():
Bucci L, Böltz S, Hagen M, Tur C, Nöthling DM, Rothe T, Wirsching A, Auth J, Wacker J, Eckstein M, Alivernini S, Bozec A, Bergmann C, D'Agostino MA, Munoz L, Rech J, Kihm L, Raimondo MG, Schett G, Grieshaber-Bouyer R:BCMA T-Cell Engager Therapy in Patients with Refractory Autoimmune Disease.N Engl J Med. 2025;393(15): 1544-1547
Mougiakakos D, Sengupta R, Gold R, Schroers R, Haghikia A, Lorente M, Pendleton M, Register A, Heesen C, Kröger N, Schett G, Mackensen A, Podoll A, Gutman J, Furie R, Bayer R, Distler JHW, Dietrich S, Krönke G, Bullinger L, Walker K:Successful generation of fully human, second generation, anti-CD19 CAR T cells for clinical use in patients with diverse autoimmune disorders.Cytotherapy. 2025;27(2): 236-246
McInnes IB, Coates LC, Mease PJ, Ogdie A, Kavanaugh A, Eder L, Schett G, Kivitz A, McGonagle D, Brennan N, Godwood A, Cullen E, Reich K, Ritchlin CT, Merola JF:Sonelokimab, an IL-17A/IL-17F-inhibiting nanobody for active psoriatic arthritis: a randomized, placebo-controlled phase 2 trial.Nat Med. 2025;31(12): 4160-4171
Bayat S, Atzinger A, Tascilar K, Kleyer A, Hueber A, Fagni F, Corte G, Schett G:FIBROBLAST ACTIVATION DETECTED BY FAPI-PET/ CT AS A SIGN OF IMPENDING RAAnn Rheum Dis. 2025;84 Suppl 1():
Garantziotis P, Nikolopoulos D, Katechis S, Temiz A, Nöthling DM, Adamichou C, Bergmann C, Sidiropoulos P, Schett G, Fanouriakis A, Boumpas DT, Bertsias G:Systemic lupus erythematosus damage risk index (SLE-DRI): a simple machine learning-based tool for identifying patients at risk for early organ damage.RMD Open. 2025;11(3):
Devakumar V, Li YN, Filla T, Rigau AR, Gyoerfi AH, Tuemerdem BS, Neelagar R, Bergmann C, Liang M, Schett G, Distler J, Matei AE:METABOLIC PHENOTYPING OF SYSTEMIC SCLEROSIS SKIN BY SPATIAL PROTEOMICSAnn Rheum Dis. 2025;84 Suppl 1(): 12-13
Seese FK, Roscher P, Coppers B, Greenfield J, Grahammer M, Kuhn S, Gupta L, Schett G, Knitza J, Liphardt AM:Toward digitally supported self-assessment of patients with idiopathic inflammatory myopathies.Arthritis Res Ther. 2025;27(1):
Ringer M, Maccataio A, Zapf R, Gaculenko A, Adam S, Aust O, Loskarn S, Luther J, Aksoy B, Popp V, Weidner D, Eck M, Munoz L, Bozec A, Uderhardt S, Bäuerle T, Schett G, Krönke G, Hüffmeier U, Frey S, Steffen U:Loss of myeloperoxidase aggravates skin and joint inflammation in the mannan-induced psoriatic arthritis mouse model.J Leukoc Biol. 2025;117(9):
Dees C, Kalyva A, Bergmann C, Kunz M, Schett G, Distler J:ACTIVATION OF NOTCH1 SIGNALING IN FIBROBLASTS IS SUFFICIENT TO INDUCE FIBROSIS AND ACTIVATES A NETWORK OF PROFIBROTIC SIGNALING CASCADESAnn Rheum Dis. 2025;83 Suppl 1():
Müller F, Schwingen NR, Hagen M, Scholz JK, Aigner M, Wirsching A, Taubmann J, Kretschmann S, Kharboutli S, Krickau T, Naumann-Bartsch N, Benintende G, Spoerl S, Rothe T, Bruns H, Grieshaber-Bouyer R, Metzler M, Blumenthal DB, Graw F, Schett G, Mackensen A, Völkl S:Comparison of the safety profiles of CD19-targeting CAR T-cell therapy in patients with SLE and B-cell lymphoma.Blood. 2025;146(9): 1088-1095
Bartsch V, Habboub B, Standfest K, Ausserwinkler M, Knitza J, Schett G, Hueber AJ:Does an Educational Video Improve Adherence to Preventive Health Measures in Rheumatic Diseases? Results from the KOMO-R Randomized Controlled TrialInn Med (Heidelb). 2025;66 Suppl 1(): S159-S160
Hong X, Xiao Y, Xu L, Shen L, Neelagar R, Devakumar V, Trinh-Minh T, Liang M, Rius Rigau A, Zhang Y, Li YN, Dees C, Györfi AH, Wolff D, Herr W, Schett G, Distler JHW, Matei AE:Combination therapies of porcupine inhibition with ruxolitinib, ibrutinib, or belumosudil in murine sclerodermatous GVHD.Blood Adv. 2025;9(6): 1261-1266
Blaskowitz PPV, Koehl N, Liphardt AM, Bouzas C, Coppers B, Petit P, Vuillerme N, Bundle V, Rudolf S, Knitza J, Raimondo MG, Labinsky H, Hatscher L, Wirsching A, Bohr D, Araujo E, Ramming A, Ramming AM, Kreienkamp M, Polacsek-Ernst R, Schett G, Morf H:IMPROVING HEALTH OUTCOMES AND REDUCING HEALTHCARE COSTS THROUGH DIGITAL MOVEMENT THERAPY: A RANDOMIZED TRIALAnn Rheum Dis. 2025;84 Suppl 1():
Weishaupt K, Ackermann J, Burger P, Chambers D, Grimm K, Weinkam R, Correa Zamora A, Auger JP, Frey B, Schett G, Krönke G:Individual subsets of alternatively-activated macrophages differentially contribute to tissue repair and the resolution of inflammation.J Immunol. 2025;214(12): 3554-3564
Regierer A, Weiss A, Behrens F, Worsch M, Pagel K, Schett G, Strangfeld A:DRUG RETENTION RATE OFTNFi BIO-ORIGINALS AND BIOSIMILARS IN axSpA AND PsA IN ROUTINE RHEUMATOLOGY CARE IN GERMANYAnn Rheum Dis. 2025;83 Suppl 1():
Györfi AH, Filla T, Polzin A, Tascilar K, Buch M, Tröbs M, Matei AE, Airo P, Balbir-Gurman A, Kuwert F, Mihai C, Kabala A, Graßhoff H, Callaghan J, Isomura Y, Mansour J, Spierings J, Tennoe AH, Selvi E, Riccieri V, Hoffmann-Vold AM, Bergmann C, Schett G, Hunzelmann N, van Laar JM, Saketkoo LA, Kuwana M, Siegert E, Riemekasten G, Distler O, du Four T, Smith V, Truchetet ME, Distler JHW, EUSTAR collaborators:Evaluation of Systemic Sclerosis Primary Heart Involvement and Chronic Heart Failure in the European Scleroderma Trials and Research Cohort.J Am Heart Assoc. 2025;14(5):
Grötsch B, Bozec A, Schett G:Models of Rheumatoid Arthritis.Methods Mol Biol. 2025;2885(): 345-357
Elewaut D, Vandercruyssen R, Devan J, Heggli I, Vlieghe C, Jacques P, Dudli S, Ravichandran K, Ramming A, Schett G, Gracey E:GDF15 mediates inflammation-associated bone loss through a brain-bone axisJ Immunol. 2025;214 Suppl _1(): 659-659
Hess A, Tascilar K, Schett G, Rech J:From whole-brain metrics to circuit-specific precision: advancing fMRI biomarkers for TNF inhibitor response in rheumatoid arthritis - Authors' reply.Lancet Rheumatol.. 2025;7(11):
Kemenes S, Chang L, Schlereth M, Noversa de Sousa R, Minopoulou I, Fenzl P, Corte G, Yalcin Mutlu M, Höner MW, Sagonas I, Coppers B, Liphardt AM, Simon D, Kleyer A, Folle L, Sticherling M, Schett G, Maier A, Fagni F:Corrigendum: Advancement and independent validation of a deep learning-based tool for automated scoring of nail psoriasis severity using the modified nail psoriasis severity index.Front Med (Lausanne). 2025;12():
Chenguiti Fakhouri S, Zhu H, Li YN, Ronicke M, Rigau AR, Dees C, Konstantinidis L, Schmid R, Matei AE, Eckstein M, Geppert C, Ludolph I, Kreuter A, Sticherling M, Berking C, Horch RE, Schett G, Distler JHW, Bergmann C:Disturbed Spatial WNT Activation-A Potential Driver of the Reticularized Skin Phenotype in Systemic Sclerosis.Arthritis Rheumatol. 2025;77(6): 740-749
Fontes V, Mueller T, Derdau J, Schett G, Neurath MF, Zundler S, Uderhardt S:3D tissue-level analysis of intestinal T cell dynamics reveals dual effects of etrasimod on recruitment and tissue exit in experimental colitisJ Crohns Colitis. 2025;19 Suppl _1(): i455-i455
Minopoulou I, Fagni F, Atzinger A, Albach F, Schett G, Krönke G, Kleyer A, Simon D:Unconventional Imaging Methods in Psoriatic Arthritis.Curr Rheumatol Rep. 2025;27(1):
McInnes IB, Eder L, Ritchlin CT, Ogdie A, Kavanaugh A, Coates LC, Schett G, Kivitz A, Brennan N, Godwood A, Thomas MR, Cullen E, Reich K, Merola JF, Mease PJ:IMPACT OF SONELOKIMAB, A NOVEL IL-17A-AND IL-17F-INHIBITING NANOBODY, ON MULTIDOMAIN CLINICAL OUTCOMES IN ACTIVE PSORIATIC ARTHRITIS: RESULTS FROM THE RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE 2 ARGO TRIALAnn Rheum Dis. 2025;84 Suppl 1():
Li YN, Filla T, Györfi AH, Liang M, Devakumar V, Micu A, Chai H, Bergmann C, Pecher AC, Henes J, Moinzadeh P, Al-Gburi S, Krieg T, Kreuter A, Wang J, Schett G, Homey B, Dietrich S, Distler JHW, Matei AE:Spatially informed phenotyping by cyclic-in-situ-hybridisation identifies novel fibroblast populations and their pathogenic niches in systemic sclerosis.Ann Rheum Dis. 2025;84(11): 1852-1864
Peng J, Zhang Y, Wang J, Zhang H, Schett G:Role of Chimeric Antigen Receptor-Expressing Cell Therapy in Immune-Mediated Kidney Diseases: A Review.Am J Kidney Dis. 2025;86(3): 360-371
Kemenes S, Chang L, Schlereth M, Noversa de Sousa R, Minopoulou I, Fenzl P, Corte G, Yalcin Mutlu M, Höner MW, Sagonas I, Coppers B, Liphart AM, Simon D, Kleyer A, Folle L, Sticherling M, Schett G, Maier A, Fagni F:Advancement and independent validation of a deep learning-based tool for automated scoring of nail psoriasis severity using the modified nail psoriasis severity index.Front Med (Lausanne). 2025;12():
Schwingen NR, Muller F, Hagen M, Wirsching A, Aigner M, Kretschmann S, Kharboutli S, Scholz J, Benintende G, Taubmann J, Krickau T, Naumann-Bartsch N, Bruns H, Grieshaber-Bouyer R, Graw F, Metzler M, Schett G, Mackensen A, Voelkl S:Distinct inflammatory and immune recovery patterns after CD19-directed CAR T-cell therapy in SLE and B-cell lymphomaBlood. 2025;146 Suppl 1(): 1947-1948
Garantziotis P, Beretta L, Lindblom J, Nikolopoulos D, Bertsias G, Hagen M, Taubmann J, Wirsching A, Bozec A, Grieshaber-Bouyer R, Schneider M, Barturen G, Boumpas D, Alarcon-Riquelme M, Schett G, Parodis I, PRECISESADS CLIN CONSORTIUM:DISTINCT MOLECULAR PROFILES OF REMISSION POST-CD19 CAR-T CELL THERAPY VERSUS STANDARD IMMUNOSUPPRESSION IN SYSTEMIC LUPUS ERYTHEMATOSUSJ Rheumatol. 2025;52 Suppl 1(): 8-8
Andreev D, Porschitz P, Weidner D, Song R, Weider M, Schett G, Gölz L, Bozec A:A multidimensional analysis of temporomandibular joint and ankle joint erosion in inflammatory arthritis.Front Immunol. 2025;16():
Auth J, Müller F, Völkl S, Bayerl N, Distler JHW, Tur C, Raimondo MG, Chenguiti Fakhouri S, Atzinger A, Coppers B, Eckstein M, Liphardt AM, Bäuerle T, Tascilar K, Aigner M, Kretschmann S, Wirsching A, Taubmann J, Hagen M, Györfi AH, Kharboutli S, Krickau T, Dees C, Spörl S, Rothe T, Harrer T, Bozec A, Grieshaber-Bouyer R, Fuchs F, Kuwert T, Berking C, Horch RE, Uder M, Mackensen A, Schett G, Bergmann C:CD19-targeting CAR T-cell therapy in patients with diffuse systemic sclerosis: a case series.Lancet Rheumatol.. 2025;7(2): e83-e93
Bartsch V, Standfest K, Ausserwinkler M, Knitza J, Schett G, Hueber AJ:Analysis of cardiovascular risk factors in rheumatology patients within the framework of the KOMO-R studyInn Med (Heidelb). 2025;66 Suppl 1(): S133-S133
Bartenschlager S, Cavallaro A, Pogarell T, Uder M, Chaudry O, Schett G, Engelke K:Impact of intravenous CT contrast agents on internal calibration techniques to determine trabecular BMD of the lumbar spine.Eur J Radiol. 2025;183():
Müller F, Atreya R, Völkl S, Aigner M, Kretschmann S, Kharboutli S, Leppkes M, Sitte S, Strobel D, Hartmann A, Mehandru S, Colombel JF, Schett G, Mackensen A, Neurath MF:CD19 CAR T-Cell Therapy in Multidrug-Resistant Ulcerative Colitis.N Engl J Med. 2025;393(12): 1239-1241
Hagen M, Wirsching A, Mueller F, Kharboutli S, Bergmann C, Boeltz S, Taubmann J, Tur C, Bucci L, Voelkl S, Aigner M, Kretschmann S, Spoerl S, Vasova I, Aletaha D, Kiener H, Natalello G, Locatelli F, D'Agostino MA, Bozec A, Hanssens L, Grieshaber-Bouyer R, Mackensen A, Schett G:SAFETY AND PRELIMINARY EFFICACY OF CD19 CAR T-CELL TREATMENT IN RHEUMATIC DISEASE-DATA FROM THE PHASE I/II CASTLE BASKET STUDYAnn Rheum Dis. 2025;84 Suppl 1():
Gerber JM, Dehdashtian E, Hu G, Gregoire C, Borie D, Bindal P, Cerny J, Geara A, Schett G, Caricchio R:Successful autologous CD19 CAR T cell therapy following severe lupus flare during immunosuppressive washout in refractory lupus nephritis.Lupus Sci Med. 2025;12(2):
Hagen M, Müller F, Wirsching A, Kharboutli S, Spoerl S, Düsing C, Krickau T, Metzler M, Völkl S, Aigner M, Kretschmann S, Vasova I, Saake M, Schliep S, Kubacki T, Hunzelmann N, Bucci L, Taubmann J, Bergmann C, Györfi AH, Dietrich S, Distler JHW, Grieshaber-Bouyer R, Mackensen A, Schett G:Local immune effector cell-associated toxicity syndrome in CAR T-cell treated patients with refractory systemic lupus erythematosus - Authors' reply.Lancet Rheumatol.. 2025;7(10): e667-e669
Corte G, Atzinger A, Tascilar K, Temiz A, Mutlu MY, de Sousa RN, Raimondo MG, Ramming A, Bayat S, Sticherling M, Kuwert T, Schmidkonz C, Schett G, Fagni F:SYNOVIAL AND ENTHESIAL FIBROBLAST ACTIVATION DETECTED BY 68GA-FAPI-04-PET/ CT PREDICTS THE DEVELOPMENT OF PSORIATIC ARTHRITIS IN PATIENTS WITH PSORIASIS AND ARTHRALGIAAnn Rheum Dis. 2025;84 Suppl 1():
Zhu L, Wang Y, Shan L, Xue Y, Schett G, Herrmann M, Liu L:Colchicine inhibits monosodium urate crystal-mediated inflammation by influencing F-actin formation.Biochim Biophys Acta Mol Basis Dis. 2025;1871(3):
Jia Y, Li R, Li Y, Kachler K, Meng X, Gießl A, Qin Y, Zhang F, Liu N, Andreev D, Schett G, Bozec A:Melanoma bone metastasis-induced osteocyte ferroptosis via the HIF1α-HMOX1 axis.Bone Res. 2025;13(1):
Georgi GM, Bachmann F, Luther J, Derer A, Heimel P, Tangl S, Kahl-Nieke B, LeBlanc A, Helms J, Schett G, Hirsch C, Gruber R, Amling M, Schinke T, Koehne T, Petersen J:The effect of Rsk2 on TNFα-mediated bone loss in the TMJ and craniofacial skeleton.BMC Oral Health. 2025;25(1):
Müller F, Wirsching A, Hagen M, Völkl S, Tur C, Raimondo MG, Taubmann J, Bucci L, Zhang L, Kretschmann S, Aigner M, Eckstein M, Spörl S, Kharboutli S, Böltz S, Atzinger A, Munoz L, Schett G, Mackensen A, Grieshaber-Bouyer R:BCMA CAR T cells in a patient with relapsing idiopathic inflammatory myositis after initial and repeat therapy with CD19 CAR T cells.Nat Med. 2025;31(6): 1793-1797
Corte G, Tascilar K, Kroker A, Minopoulou I, Kleyer A, Simon D, Schett G, Fagni F:CANNABIS-BASED PRODUCTS FOR PAIN MANAGEMENT IN RHEUMATIC DISEASES: HIGH PATIENT-REPORTED EFFICACY AND OPENNESS TO THERAPY DESPITE LOW PRESCRIPTION RATES IN GERMANY AFTER LEGALIZATION OF NON-MEDICAL CANNABISAnn Rheum Dis. 2025;84 Suppl 1(): 1815-1816
Bergmann C, Chenguiti Fakhouri S, Trinh-Minh T, Filla T, Rius Rigau A, Ekici AB, Merlevede B, Hallenberger L, Zhu H, Dees C, Matei AE, Auth J, Györfi AH, Zhou X, Rauber S, Bozec A, Dickel N, Liang C, Kunz M, Schett G, Distler JHW:Mutual Amplification of GLI2/Hedgehog and Transcription Factor JUN/AP-1 Signaling in Fibroblasts in Systemic Sclerosis: Potential Implications for Combined Therapies.Arthritis Rheumatol. 2025;77(1): 92-98
Muller F, Hagen M, Spoerl S, Wirsching A, Kharboutli S, Kretschmann S, Tascilar K, Taubmann J, Bucci L, Raimondo M, Bergmann C, Tur C, Munoz L, Vasova I, Gerbitz A, Spriewald B, Ginnarelli D, Locatelli F, D'agostino MA, Hanssen L, Bozec A, Grieshaber-Boyer R, Miltenyi S, Aigner M, Voelkl S, Schett G, Mackensen A:Safety and preliminary efficacy of anti-CDI9 CART cells zorpocabtagene-autoleucel in systemic autoimmune diseases: Final analysis of the castle trialBlood. 2025;146 Suppl 1(): 2380-2381
Heming JN, Margraf A, Najder K, Germena G, Richter M, Cappenberg A, Henke K, Bardel B, Schemmelmann L, Oguama M, Lindental P, Amini W, Sobocik J, Schett G, Krönke G, Block H, Rossaint J, Soehnlein O, Zarbock A:CD45 and CD148 Are Critically Involved in Neutrophil Recruitment and Function During Inflammatory Arthritis in Mice.Cells. 2025;14(15):
Li YN, Filla T, Gyoerfi AH, Liang M, Devakumar V, Micu A, Chai H, Bergmann C, Pecher AC, Henes J, Moinzadeh P, Al-Gburi S, Krieg T, Kreuter A, Wang J, Schett G, Homey B, Dietrich S, Distler J, Matei AE:IDENTIFICATION OF FIBROBLAST POPULATIONS AND THEIR PATHOGENIC NICHES IN SYSTEMIC SCLEROSIS BY IMAGING-BASED SPATIAL TRANSCRIPTOMICSAnn Rheum Dis. 2025;84 Suppl 1():
Li Y, Li S, Zhao X, Sheng J, Xue L, Schett G, Shi C, Hu B, Wang X, Chen Z:Fourth-generation chimeric antigen receptor T-cell therapy is tolerable and efficacious in treatment-resistant rheumatoid arthritis.Cell Res. 2025;35(3): 220-223
Karisik A, Dejakum B, Moelgg K, Granna J, Felicetti S, Pechlaner R, Mayer-Suess L, Toell T, Buergi L, Scherer L, Willeit K, Heidinger M, Lang C, Ferrari J, Krebs S, Kleyhons R, Resch H, Willeit J, Seekircher L, Tschiderer L, Willeit P, Sykora M, Schett G, Lang W, Knoflach M, Kiechl S, Boehme C:Incidence, characteristics, and consequences of fractures after acute ischemic stroke and TIA-A prospective cohort study.Int J Stroke. 2025;20(9): 1141-1149
Bucci L, Rothe T, Mueller F, Taubmann J, Hagen M, Bergmann C, Tur C, Munoz L, Wilhelm A, Gerlach R, Schaefer S, Voelkl S, Aigner M, Grieshaber-Bouyer R, Kroenke G, Bozec A, Winkler T, Mackensen A, Schett G:EFFECTS OF CAR-T CELL TREATMENT ON B CELL IMMUNITY IN SYSTEMIC AUTOIMMUNE DISEASESAnn Rheum Dis. 2025;83 Suppl 1():
Kragsnaes MS, Gilbert BTP, Sofíudóttir BK, Rooney CM, Hansen SM, Mauro D, Mullish BH, Bergot AS, Mankia KS, Goel N, Bakland G, Johnsen PH, Miguens Blanco J, Li S, Dumas E, Lage-Hansen PR, Wagenaar C, Bakdash G, Robinson M, Kristiansen K, Marchesi JR, Schett G, Zaiss MM, Orlu M, van Schaadenburg D, Scher JU, McGonagle D, Elewaut D, Breban M, Tugwell P, Finckh A, Ciccia F, Kriegel MA, Daien C, Ellingsen T, Christensen R, EULAR Study Group MICMUC , Kragsnaes MS, Gilbert BTP, Rooney CM, Mauro D, Mullish BH, Bergot AS, Mankia KS, Goel N, Bakland G, Johnsen PH, Raanes SS, Blanco JM, Li S, Dumas E, Wagenaar C, Kastbom A, Rodriguez VR, Guggino G, Bakdash G, Robinson M, Kristiansen K, Marchesi JR, Schett G, Zaiss MM, McGonagle D, Schaadenburg DV, Scher JU, Elewaut D, Breban M, Finckh A, Ciccia F, Kriegel MA, Daien C, Ellingsen T:Efficacy and safety of microbiota-targeted therapeutics in autoimmune and inflammatory rheumatic diseases: protocol for a systematic review and meta-analysis of randomised controlled trials.BMJ Open. 2025;15(12):
Tur C, Eckstein M, Bucci L, Auth J, Bergmann C, Rauber S, Hagen M, Nöthling DM, Böltz S, Wirsching A, Tascilar K, Fagni F, Corte G, Rius Rigau A, Qin Y, Garantziotis P, Taubmann J, Wacker J, Ramming A, D Agostino MA, Rauch S, Hartmann A, Müller F, Mackensen A, Grieshaber-Bouyer R, Schett G, Bozec A, Raimondo MG:Effects of different B-cell-depleting strategies on the lymphatic tissue.Ann Rheum Dis. 2025;84(12): 2065-2074
Ostendorf L, Garantziotis P, Huang FY, Schett G, Accelerating Medicines Partnership: RA/SLE Network , Lederer JA, Fava A, Rao DA, Grieshaber-Bouyer R:Neutrophil Heterogeneity Identifies an Association of LAMP1 With Proliferative Lupus Nephritis.Eur J Immunol. 2025;55(8):
Schuster L, Henes J, Diener M, Mühlensiepen F, Andreica I, Hueber A, Schett G, Knitza J:[Measurement of disease-related knowledge of patients with axial spondyloarthritis-Development and application of the G-ASKQ7 questionnaire].Z Rheumatol. 2025;84(5): 404-409
Dürholz K, Ehnes L, Linnerbauer M, Schmid E, Danzer H, Hinzpeter-Schmidt M, Lößlein L, Amend L, Frech M, Azizov V, Schälter F, Gessner A, Lucas S, Lesker TR, Taudte RV, Hofmann J, Beyer F, Bootz-Maoz H, Reich Y, Romano H, Mauro D, Beckervordersandforth R, Kragsnaes MS, Ellingsen T, Xiang W, Haghikia A, Akdis CA, Ciccia F, Bäuerle T, Sarter K, Strowig T, Yissachar N, Schett G, Rothhammer V, Zaiss MM:Gut-specific histamine 3 receptor signaling orchestrates microglia-dependent resolution of peripheral inflammation.J Clin Invest. 2025;135(18):
Keret S, Kaly L, Schett G, Bergmann C, Feldman E, Zuckerman T, Yehudai-Ofir D, Shouval A, Awisat A, Rosner I, Rozenbaum M, Boulman N, Sawaed A, Hardak E, Henes J, Slobodin G, Rimar D:Neutrophil-to-lymphocyte ratio as a biomarker for clinical response after autologous haematopoietic stem cell transplantation in systemic sclerosis.Rheumatology (Oxford). 2025;64(5): 3160-3165
Maeda Y, Wirtz S, Hagen M, Rothe T, Wirsching A, Grieshaber-Bouyer R, Gimaev I, Schmid E, Kriegel M, Mueller F, Mackensen A, Schett G, Zaiss MM:ALTERED GUT MICROBIOTA COMPOSITION IN AUTOIMMUNE DISEASE PATIENTS UNDERGOING CD19-CAR T-CELL THERAPYAnn Rheum Dis. 2025;84 Suppl 1():
Müller F, Hagen M, Schett G, Mackensen A:[CAR T cells in non-malignant diseases].Inn Med (Heidelb). 2025;66(8): 810-817
Grieshaber-Bouyer R, Garantziotis P, Ostendorf L, Schoen J, Schett G, Rao D:NEUTROPHIL-DERIVED LAMP1 IS ASSOCIATED WITH PROLIFERATIVE LUPUS NEPHRITISAnn Rheum Dis. 2025;83 Suppl 1():
Hsieh EWY, Chung JB, Amin A, Askanase AD, Bartok B, Brunetta P, Carrasco-Alfonso MJ, Coney C, Cooper JC, Dall'Era M, Delev N, Eldred A, Furie RA, Garces S, Groover K, Harrington M, Hogan JJ, Imperato GH, Jackson M, Jackson SW, Jongco AM, Karis E, Koegel A, König MF, Koretzky G, Kumar V, Morand E, Payne AS, Popat V, Rizvi N, Rohan P, Sadelain M, Schett G, Singh AP, van Vollenhoven RF, Zack D, Lupus ABC CAR T Working Group , Amin A, Askanase AD, Bartok B, Bell S, Bowden A, Bridges L, Brunetta P, Carrasco-Alfonso MJ, Chung J, Coney C, Cooper JC, Dall'Era M, Delev N, Diehl S, Eldred A, Furie RA, Garces S, Graef T, Groover K, Hsieh EY, Hogan J, Imperato G, Jackson M, Jackson S, Jongco AM, Karis E, Kim N, Koch A, Koegel A, Konig MF, Koretzky G, Kumar V, Ma Y, Matzkies F, Morand E, Nguyen H, Panico E, Payne A, Peakman M, Peterson R, Popat V, Rizvi N, Rohan P, Sadelain M, Schett G, Singh AP, Sridharan S, Staeva TP, Vollenhoven RV, Wyse K, Zack D:Key considerations for advancing chimeric antigen receptor (CAR) T-cell therapy for systemic lupus erythematosus (SLE): a multi-partner/disciplinary working group perspective.RMD Open. 2025;11(4):
Temiz A, Tascilar K, Kleyer A, Hueber AJ, Hartmann F, Schett G, Bayat S:Comparison of long-term efficacy, tolerability and drug survival rates of baricitinib as monotherapy or combination therapy in RA patients: data from a real-world prospective cohort study.RMD Open. 2025;11(4):

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