Prof. Dr. M. Zaiss

Publikationen: Prof. Dr. rer. nat. M. Zaiss

Zundler S, Günther C, Kremer AE, Zaiss MM, Rothhammer V, Neurath MF: Gut immune cell trafficking: inter-organ communication and immune-mediated inflammation. Nat Rev Gastroenterol Hepatol. 2023;20(1): 50-64
Moyat M, Lebon L, Perdijk O, Wickramasinghe LC, Zaiss MM, Mosconi I, Volpe B, Guenat N, Shah K, Coakley G, Bouchery T, Harris NL: Microbial regulation of intestinal motility provides resistance against helminth infection. Mucosal Immunol. 2022;15(6): 1283-1295
Schälter F, Frech M, Dürholz K, Lucas S, Sarter K, Lebon L, Esser-von Bieren J, Dubey LK, Voehringer D, Schett G, Harris NL, Zaiss MM: Acetate, a metabolic product of Heligmosomoides polygyrus, facilitates intestinal epithelial barrier breakdown in a FFAR2-dependent manner. Int J Parasitol. 2022;52(9): 591-601
Dürholz K, Schmid E, Frech M, Azizov V, Otterbein N, Lucas S, Rauh M, Schett G, Bruns H, Zaiss MM: Microbiota-Derived Propionate Modulates Megakaryopoiesis and Platelet Function. Front Immunol. 2022;13():
Omata Y, Okada H, Uebe S, Izawa N, Ekici AB, Sarter K, Saito T, Schett G, Tanaka S, Zaiss MM: Interspecies Single-Cell RNA-Seq Analysis Reveals the Novel Trajectory of Osteoclast Differentiation and Therapeutic Targets. JBMR Plus. 2022;6(7):
Omata Y, Frech M, Saito T, Schett G, Zaiss MM, Tanaka S: Inflammatory Arthritis and Bone Metabolism Regulated by Type 2 Innate and Adaptive Immunity. Int J Mol Sci. 2022;23(3):
Frech M, Omata Y, Schmalzl A, Wirtz S, Taher L, Schett G, Zaiss MM, Sarter K: Btn2a2 Regulates ILC2-T Cell Cross Talk in Type 2 Immune Responses. Front Immunol. 2022;13():
Duscha A, Hegelmaier T, Dürholz K, Desel C, Gold R, Zaiss MM, Haghikia A: Propionic acid beneficially modifies osteoporosis biomarkers in patients with multiple sclerosis. Therap Adv Neurol Dis. 2022;15():
Martinsson K, Dürholz K, Schett G, Zaiss MM, Kastbom A: Higher serum levels of short-chain fatty acids are associated with non-progression to arthritis in individuals at increased risk of RA. Ann Rheum Dis. 2022;81(3): 445-447
Zaiss MM, Joyce Wu HJ, Mauro D, Schett G, Ciccia F: The gut-joint axis in rheumatoid arthritis. Nat Rev Rheumatol. 2021;17(4): 224-237
Schälter F, Dürholz K, Bucci L, Burmester G, Caporali R, Figuereido C, Cobra JF, Manger B, Zaiss MM, Schett G: Does methotrexate influence COVID-19 infection? Case series and mechanistic data. Arthritis Res Ther. 2021;23(1):
Brandl C, Bucci L, Schett G, Zaiss MM: Crossing the barriers: Revisiting the gut feeling in rheumatoid arthritis. Eur J Immunol. 2021;51(4): 798-810
Friščić J, Dürholz K, Chen X, Engdahl C, Möller L, Schett G, Zaiss MM, Hoffmann MH: Dietary Derived Propionate Regulates Pathogenic Fibroblast Function and Ameliorates Experimental Arthritis and Inflammatory Tissue Priming. Nutrients. 2021;13(5):
Bai Y, Li Y, Marion T, Tong Y, Zaiss MM, Tang Z, Zhang Q, Liu Y, Luo Y: Resistant starch intake alleviates collagen-induced arthritis in mice by modulating gut microbiota and promoting concomitant propionate production. J Autoimmun. 2021;116():
Hofbauer D, Mougiakakos D, Broggini L, Zaiss M, Büttner-Herold M, Bach C, Spriewald B, Neumann F, Bisht S, Nolting J, Zeiser R, Hamarsheh S, Eberhardt M, Vera J, Visentin C, De Luca CMG, Moda F, Haskamp S, Flamann C, Böttcher M, Bitterer K, Völkl S, Mackensen A, Ricagno S, Bruns H: β2-microglobulin triggers NLRP3 inflammasome activation in tumor-associated macrophages to promote multiple myeloma progression. Immunity. 2021;54(8): 1772-1787.e9
Azizov V, Zaiss MM: Alcohol Consumption in Rheumatoid Arthritis: A Path through the Immune System. Nutrients. 2021;13(4):
Frech M, Schuster G, Andes FT, Schett G, Zaiss MM, Sarter K: RANKL-Induced Btn2a2 - A T Cell Immunomodulatory Molecule - During Osteoclast Differentiation Fine-Tunes Bone Resorption. Front Endocrinol (Lausanne). 2021;12():
Azizov V, Sokolova MV, Sarter K, Temchura V, Steffen (Nee Harre) U, Herrmann M, Schett G, Zaiss M: WHY DOES ALCOHOL INHIBIT ARTHRITIS? - AN EXPLANATION OF THE MECHANISM OF ARTHRITIS INHIBITION BY ETHANOL Ann Rheum Dis. 2020;79 Suppl 1(): 151-151
Simon D, Tascilar K, Krönke G, Kleyer A, Zaiss MM, Heppt F, Meder C, Atreya R, Klenske E, Dietrich P, Abdullah A, Kliem T, Corte G, Morf H, Leppkes M, Kremer AE, Ramming A, Pachowsky M, Schuch F, Ronneberger M, Kleinert S, Maier C, Hueber AJ, Manger K, Manger B, Berking C, Tenbusch M, Überla K, Sticherling M, Neurath MF, Schett G: Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion. Nat Commun. 2020;11(1):
Rapin A, Chuat A, Lebon L, Zaiss MM, Marsland BJ, Harris NL: Infection with a small intestinal helminth, Heligmosomoides polygyrus bakeri, consistently alters microbial communities throughout the murine small and large intestine Int J Parasitol. 2020;50(1): 35-46
Dürholz K, Hofmann J, Iljazovic A, Häger J, Lucas S, Sarter K, Strowig T, Bang H, Rech J, Schett G, Zaiss MM: Dietary Short-Term Fiber Interventions in Arthritis Patients Increase Systemic SCFA Levels and Regulate Inflammation. Nutrients. 2020;12(10):
Zaiss M, Taijc N, Sarter K, Azizov V, Bucci L, Luo Y, Canete JDD, Ciccia F, Schett G: MICROBIOTA-INDUCED INTESTINAL BARRIER DYSFUNCTION PRECEDES THE ONSET OF ARTHRITIS AND ALLOWS THE SHUTTLING OF IMMUNE CELLS FROM THE GUT THE JOINTS Ann Rheum Dis. 2020;79 Suppl 1(): 154-154
Azizov V, Dietel K, Steffen F, Dürholz K, Meidenbauer J, Lucas S, Frech M, Omata Y, Tajik N, Knipfer L, Kolenbrander A, Seubert S, Lapuente D, Sokolova MV, Hofmann J, Tenbusch M, Ramming A, Steffen U, Nimmerjahn F, Linker R, Wirtz S, Herrmann M, Temchura V, Sarter K, Schett G, Zaiss MM: Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis. Nat Commun. 2020;11(1):
Tajik N, Frech M, Schulz O, Schälter F, Lucas S, Azizov V, Dürholz K, Steffen F, Omata Y, Rings A, Bertog M, Rizzo A, Iljazovic A, Basic M, Kleyer A, Culemann S, Krönke G, Luo Y, Überla K, Gaipl US, Frey B, Strowig T, Sarter K, Bischoff SC, Wirtz S, Cañete JD, Ciccia F, Schett G, Zaiss MM: Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis. Nat Commun. 2020;11(1):
Omata Y, Frech M, Lucas S, Primbs T, Knipfer L, Wirtz S, Kadono Y, Saito T, Tanaka S, Sarter K, Schett G, Zaiss MM: Type 2 innate lymphoid cells inhibit the differentiation of osteoclasts and protect from ovariectomy-induced bone loss. Bone. 2020;136():
Frech M, Knipfer L, Wirtz S, Zaiss MM: An in vivo gene delivery approach for the isolation of reasonable numbers of type 2 innate lymphoid cells. MethodsX. 2020;7():
Simon D, Tascilar K, Kronke G, Kleyer A, Zaiss M, Heppt F, Meder C, Atreya R, Klenske E, Dietrich P, Abdullah A, Kliem T, Corte G, Morf H, Leppkes M, Kremer A, Ramming A, Pachowsky M, Schuch F, Ronneberger M, Kleinert S, Maier C, Hueber A, Manger K, Manger B, Berking C, Tenbusch M, Ueberla K, Sticherling M, Neurath M, Schett G: Patients Receiving Cytokine Inhibitors Have Low Prevalence of SARS-CoV-2 Infection Arthritis Rheumatol. 2020;72 Suppl 10():
Tajik N, Frech M, Brandl C, Canete J, Ciccia F, Schett G, Zaiss M: Microbiota-induced Intestinal Barrier Dysfunction Initiates the Shuttling of Immune Cells from the Gut to the Joints Arthritis Rheumatol. 2020;72 Suppl 10():
Duscha A, Gisevius B, Hirschberg S, Yissachar N, Stangl GI, Eilers E, Bader V, Haase S, Kaisler J, David C, Schneider R, Troisi R, Zent D, Hegelmaier T, Dokalis N, Gerstein S, Del Mare-Roumani S, Amidror S, Staszewski O, Poschmann G, Stühler K, Hirche F, Balogh A, Kempa S, Träger P, Zaiss MM, Holm JB, Massa MG, Nielsen HB, Faissner A, Lukas C, Gatermann SG, Scholz M, Przuntek H, Prinz M, Forslund SK, Winklhofer KF, Müller DN, Linker RA, Gold R, Haghikia A: Propionic Acid Shapes the Multiple Sclerosis Disease Course by an Immunomodulatory Mechanism. Cell. 2020;180(6): 1067-1080.e16
Sokolova MV, Simon D, Nas K, Zaiss MM, Luo Y, Zhao Y, Rech J, Schett G: A set of serum markers detecting systemic inflammation in psoriatic skin, entheseal, and joint disease in the absence of C-reactive protein and its link to clinical disease manifestations. Arthritis Res Ther. 2020;22(1):
Hofbauer D, Mougiakakos D, Ricagno S, Buettner-Herold M, Neumann F, Bisht S, Zeiser R, Hamaresh S, Zaiss M, Eberhardt M, Voelkl S, Boettcher M, Bitterer K, Mackensen A, Bruns H: beta(2)-microglobulin - a trigger for NLRP3 inflammasome activation in tumor-associated macrophages promoting multiple myeloma cell progression Oncology Research and Treatment. 2020;43 Suppl 4(SUPPL 4): 101-101
Luu M, Pautz S, Kohl V, Singh R, Romero R, Lucas S, Hofmann J, Raifer H, Vachharajani N, Carrascosa LC, Lamp B, Nist A, Stiewe T, Shaul Y, Adhikary T, Zaiss MM, Lauth M, Steinhoff U, Visekruna A: The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes Nat Commun. 2019;10():
Azizov V, Dietel K, Kolenbrander A, Seubert S, Steffen F, Meidenbauer J, Steffen U, Hofmann J, Nimmerjahn F, Linker R, Wirtz S, Sarter K, Herrmann M, Temchura V, Schett G, Zaiss M: Ethanol consumption decreases autoantibody titers by blocking IL-21 secretion of Tfh cells during the development of arthritis Eur J Immunol. 2019;49(): 199-199
Sokolova M, Nas K, Luo YB, Simon D, Zhao Y, Rech J, Zaiss M, Schett G: A SET OF INFLAMMATORY MARKERS ALLOWING TO DETECT SYSTEMIC INFLAMMATION IN PSORIATIC SKIN, ENTHESEAL AND JOINT DISEASE IN THE ABSENCE OF CRP AND THEIR LINK TO CLINICAL DISEASE MANIFESTATION Ann Rheum Dis. 2019;78(): 175-176
Azizov V, Dietel K, Kolenbrander A, Seubert S, Steffen F, Meidenbauer J, Steffen U, Hofmann J, Nimmerjahn F, Linker R, Wirtz S, Herrmann M, Sarter K, Temchura V, Schett G, Zaiss M: Ethanol consumption inhibits the development of autoimmunity by blocking IL-21 secretion in T-FH cells Eur J Immunol. 2019;49(): 936-936
Zaiss MM, Jones RM, Schett G, Pacifici R: The gut-bone axis: how bacterial metabolites bridge the distance J Clin Invest. 2019;129(8): 3018-3028
Zaiss M: HOW THE GUT INFLUENCES THE IMMUNE SYSTEM Ann Rheum Dis. 2019;78(): 3-3
Frommer KW, Hasseli R, Schaeffler A, Lange U, Rehart S, Steinmeyer J, Rickert M, Sarter K, Zaiss MM, Culmsee C, Ganjam G, Michels S, Mueller-Ladner U, Neumann E: Free Fatty Acids in Bone Pathophysiology of Rheumatic Diseases Front Immunol. 2019;10():
Hofbauer D, Mougiakakos D, Buettner-Herold M, Neumann F, Nolting J, Bisht S, Zeiser R, Hamarsheh S, Ricagno S, Zaiss M, Eberhardt M, Boettcher M, Bitterer K, Mackensen A, Bruns H: beta(2)-m - a Trigger for NLRP3 Inflammasome Activation within Macrophages Promoting Multiple Myeloma Cell Proliferation Blood. 2019;134 Suppl 1():
Haeger J, Bang H, Hagen M, Frech M, Traeger P, Sokolova MV, Steffen U, Tascilar K, Sarter K, Schett G, Rech J, Zaiss MM: The Role of Dietary Fiber in Rheumatoid Arthritis Patients: A Feasibility Study Nutrients. 2019;11(10):
Tajik N, Schulz O, Frech M, Lucas S, Sarter K, Schett G, Zaiss M: Targeting intestinal tight junctions to inhibit onset of arthritis Eur J Immunol. 2019;49(): 136-137
Zaiss MM, Hall C, McGowan NWA, Babb R, Devlia V, Lucas S, Meghji S, Henderson B, Bozec A, Schett G, David JP, Panayi GS, Grigoriadis AE, Corrigall VM: Binding Immunoglobulin Protein (BIP) Inhibits TNF-α-Induced Osteoclast Differentiation and Systemic Bone Loss in an Erosive Arthritis Model. ACR Open Rheumatol. 2019;1(6): 382-393
Lucas S, Omata Y, Hofmann J, Böttcher M, Iljazovic A, Sarter K, Albrecht O, Schulz O, Krishnacoumar B, Krönke G, Herrmann M, Mougiakakos D, Strowig T, Schett G, Zaiss MM: Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss. Nat Commun. 2018;9(1): 55
Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar , Erny D, Stefanowski J, Rogell L, Klein C, Gharun K, Follo M, Seidl M, Kremer B, Munke N, Senges J, Fliegauf M, Aschman T, Pfeifer D, Sarrazin S, Sieweke MH, Wagner D, Dierks C, Haaf T, Ness T, Zaiss MM, Voll RE, Deshmukh SD, Prinz M, Goldmann T, Holscher C, Hauser AE, Lopez-Contreras AJ, Grun D, Gorgoulis V, Diefenbach A, Henneke P, Triantafyllopoulou A: DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas (vol 167, pg 1264, 2016) Cell. 2018;174(5): 1325-1326
Zaiss MM: HOW THE GUT MICROBIOTA AND ITS METABOLITES IMPACT ON BONE HOMEOSTASIS Ann Rheum Dis. 2018;77(): 38-38
Omata Y, Frech M, Primbs T, Lucas S, Andreev D, Scholtysek C, Sarter K, Kindermann M, Yeremenko N, Baeten DL, Andreas N, Kamradt T, Bozec A, Ramming A, Krönke G, Wirtz S, Schett G, Zaiss MM: Group 2 Innate Lymphoid Cells Attenuate Inflammatory Arthritis and Protect from Bone Destruction in Mice. Cell Rep. 2018;24(1): 169-180
Bozec A, Zaiss MM: T Regulatory Cells in Bone Remodelling. Curr Osteoporos Rep. 2017;15(3): 121-125
Lucas S, Omata Y, Boettcher M, Hofmann J, Krishnacoumar B, Kroenke G, Mougiakakos D, Iljazovic A, Sonnewald U, Strowig T, Schett G, Zaiss M: Short chain fatty acids are potent regulators of systemic bone mass and protect for pathological bone loss by inhibiting osteoclasts Eur J Immunol. 2017;47(): 217-217
Rauber S, Luber M, Weber S, Maul L, Soare A, Wohlfahrt T, Bozec A, Herrmann M, Zaiss M, Fearon U, Veale DJ, Canete J, Distler O, Rivellese F, Pitzalis C, Schett G, Distler J, Ramming A: IL-9-Producing Innate Lymphoid Cells - Keyplayers That Orchestrate Resolution of Chronic Inflammation in Arthritis Arthritis Rheumatol. 2017;69():
Liu P, Lee S, Knoll J, Rauch A, Ostermay S, Luther J, Malkusch N, Lerner UH, Zaiss MM, Neven M, Wittig R, Rauner M, David JP, Bertolino P, Zhang CX, Tuckermann JP: Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing osteoporosis. Cell Death Differ. 2017;24(4): 672-682
Omata Y, Lucas S, Garcia M, Wirtz S, Bozec A, Schett G, Zaiss MM: REGULATION OF ARTHRITIS BY TYPE 2 INNATE LYMPHOID CELLS Ann Rheum Dis. 2017;76 1(): A3-A3
Rauber S, Luber M, Weber S, Maul L, Soare A, Wohlfahrt T, Lin NY, Dietel K, Bozec A, Herrmann M, Kaplan MH, Weigmann B, Zaiss MM, Fearon U, Veale DJ, Cañete JD, Distler O, Rivellese F, Pitzalis C, Neurath MF, McKenzie ANJ, Wirtz S, Schett G, Distler JHW, Ramming A: Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells. Nat Med. 2017;23(8): 938-944
Ackermann JA, Hofheinz K, Zaiss MM, Krönke G: The double-edged role of 12/15-lipoxygenase during inflammation and immunity. Biochim Biophys Acta Mol Cell Biol Lipids. 2017;1862(4): 371-381
Sarter K, Kulagin M, Schett G, Harris NL, Zaiss MM: Inflammatory arthritis and systemic bone loss are attenuated by gastrointestinal helminth parasites. Autoimmunity. 2017;50(3): 151-157
Zaiss MM, Harris NL: Interactions between the intestinal microbiome and helminth parasites. Parasite Immunol. 2016;38(1): 5-11
Zaiss MM, Rapin A, Lebon L, Dubey LK, Mosconi I, Sarter K, Piersigilli A, Menin L, Walker AW, Rougemont J, Paerewijck O, Geldhof P, McCoy KD, Macpherson AJ, Croese J, Giacomin PR, Loukas A, Junt T, Marsland BJ, Harris NL: The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation. Immunity. 2015;43(5): 998-1010
Mosconi I, Dubey LK, Volpe B, Esser-von Bieren J, Zaiss MM, Lebon L, Massacand JC, Harris NL: Parasite Proximity Drives the Expansion of Regulatory T Cells in Peyer's Patches following Intestinal Helminth Infection. Infect Immun. 2015;83(9): 3657-65
Boyle DL, Hammaker D, Edgar M, Zaiss MM, Teufel S, David JP, Schett G, Firestein GS: Differential roles of MAPK kinases MKK3 and MKK6 in osteoclastogenesis and bone loss. PLoS ONE. 2014;9(1): e84818
Bozec A, Zaiss MM, Kagwiria R, Voll R, Rauh M, Chen Z, Mueller-Schmucker S, Kroczek RA, Heinzerling L, Moser M, Mellor AL, David JP, Schett G: T Cell Costimulation Molecules CD80/86 Inhibit Osteoclast Differentiation by Inducing the IDO/Tryptophan Pathway. Sci Transl Med. 2014;6(235): 235ra60
Scholtysek C, Katzenbeisser J, Fu H, Uderhardt S, Ipseiz N, Stoll C, Zaiss MM, Stock M, Donhauser L, Böhm C, Kleyer A, Hess A, Engelke K, David JP, Djouad F, Tuckermann JP, Desvergne B, Schett G, Krönke G: PPAR?/? governs Wnt signaling and bone turnover. Nat Med. 2013;19(5): 608-13
Mueller-Schmucker S, Axmann R, Herman S, Zaiss M, Le Bars M, Harrer T, Schett GA: Abatacept Monotherapy Effectively Reduces the Frequency of Osteoclast Precursor Cells in the Peripheral Blood of Patients with Rheumatoid Arthritis and Inhibits Their Differentiation Into Osteoclasts. Arthritis Rheum. 2012;64 Suppl S(10): S915-S915
Zwerina K, Koenders M, Hueber A, Marijnissen RJ, Baum W, Heiland GR, Zaiss M, McLnnes I, Joosten L, van den Berg W, Zwerina J, Schett G: Anti IL-17A therapy inhibits bone loss in TNF-?-mediated murine arthritis by modulation of the T-cell balance. Eur J Immunol. 2012;42(2): 413-23
Böhm C, Derer A, Axmann R, Hillienhoff U, Zaiss MM, Luther J, Zech C, Stock M, Scholtysek C, Engelke K, Hess A, Tuckermann JP, Schett G, David JP: RSK2 protects mice against TNF-induced bone loss. J Cell Sci. 2012;125(Pt 9): 2160-71
Gückel E, Frey S, Zaiss MM, Schett G, Ghosh S, Voll RE: Cell-intrinsic NF-?B activation is critical for the development of natural regulatory T cells in mice. PLoS ONE. 2011;6(5): e20003
Zaiss MM, Kurowska-Stolarska M, Böhm C, Gary R, Scholtysek C, Stolarski B, Reilly J, Kerr S, Millar NL, Kamradt T, McInnes IB, Fallon PG, David JP, Liew FY, Schett G: IL-33 Shifts the Balance from Osteoclast to Alternatively Activated Macrophage Differentiation and Protects from TNF-{alpha}-Mediated Bone Loss. J Immunol. 2011;186(11): 6097-105
Schulze J, Bickert T, Beil FT, Zaiss MM, Albers J, Wintges K, Streichert T, Klaetschke K, Keller J, Hissnauer TN, Spiro AS, Gessner A, Schett G, Amling M, McKenzie AN, Horst AK, Schinke T: Interleukin-33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells. J Bone Miner Res. 2011;26(4): 704-17
Luther J, Driessler F, Megges M, Hess A, Herbort B, Mandic V, Zaiss MM, Reichardt A, Zech C, Tuckermann JP, Calkhoven CF, Wagner EF, Schett G, David JP: Elevated Fra-1 expression causes severe lipodystrophy. J Cell Sci. 2011;124(Pt 9): 1465-76
Böhm C, Zaiss MM, Axmann R, Hess A, Engelke K, Kollias G, Schett G, David JP: ERK- ACTIVATED KINASE RSK2 PROTECTS AGAINST INFLAMMATORY ARTHRITIS- INDUCED BONE DESTRUCTION BY OPPOSING THE TUMOUR NECROSIS FACTOR alpha- MEDIATED INHIBITION OF BONE FORMATION Ann Rheum Dis. 2010;69 Suppl. (): A60 -
Rauch A, Seitz S, Baschant U, Schilling AF, Illing A, Stride B, Kirilov M, Mandic V, Takacz A, Schmidt-Ullrich R, Ostermay S, Schinke T, Spanbroek R, Zaiss MM, Angel PE, Lerner UH, David JP, Reichardt HM, Amling M, Schütz G, Tuckermann JP: Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor. Cell Metab. 2010;11(6): 517-31
Zaiss MM, Sarter K, Hess A, Engelke K, Böhm C, Nimmerjahn F, Voll R, Schett G, David JP: Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation. Arthritis Rheum. 2010;62(8): 2328-38
Krönke G, Uderhardt S, Kim KA, Stock M, Scholtysek C, Zaiss MM, Surmann-Schmitt C, Luther J, Katzenbeisser J, David JP, Abdollahi-Roodsaz S, Tran K, Bright JM, Binnerts ME, Akhmetshina A, Böhm C, Distler JH, Joosten LA, Schett G, Abo A: R-spondin 1 protects against inflammatory bone damage during murine arthritis by modulating the Wnt pathway. Arthritis Rheum. 2010;62(8): 2303-12
Zaiss M, McGowan N, David JP, Grigoriadis A, Schett G, Panayi G, Corrigall V: REGULATION OF OSTEOCLAST DIFFERENTIATION AND FUNCTION BY BIP Ann Rheum Dis. 2010;69 Suppl 2():
Zaiss MM, Frey B, Hess A, Zwerina J, Luther J, Nimmerjahn F, Engelke K, Kollias G, Hünig T, Schett G, David JP: Regulatory T cells protect from local and systemic bone destruction in arthritis. J Immunol. 2010;184(12): 7238-46
Krönke G, Katzenbeisser J, Uderhardt S, Zaiss MM, Scholtysek C, Schabbauer G, Zarbock A, Koenders MI, Axmann R, Zwerina J, Baenckler HW, van den Berg W, Voll RE, Kuhn H, Joosten LA, Schett G: 12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis. J Immunol. 2009;183(5): 3383-9
Böhm C, Hayer S, Kilian A, Zaiss MM, Finger S, Hess A, Engelke K, Kollias G, Krönke G, Zwerina J, Schett G, David JP: The alpha-isoform of p38 MAPK specifically regulates arthritic bone loss. J Immunol. 2009;183(9): 5938-47
Frey B, Gaipl US, Sarter K, Zaiss MM, Stillkrieg W, Rödel F, Schett G, Herrmann M, Fietkau R, Keilholz L: Whole body low dose irradiation improves the course of beginning polyarthritis in human TNF-transgenic mice. Autoimmunity. 2009;42(4): 346-8
Axmann R, Polzer K, Herman S, Franz S, Zaiss M, Zwerina J, Smolen J, Schett G: CTLA-4 directly inhibits osteoclast formation Ann Rheum Dis. 2008;67 Suppl 1(): A23-A24
Zaiss M, Axmann R, Zwerina J, Polzer K, Gückel E, Skapenko A, Schulze-Koops H, Horwood N, Cope A, Schett G: Regulatory T cells suppress osteoclast formation: A new link between the immune system and bone Ann Rheum Dis. 2008;67 Suppl. (): 095 -
Axmann R, Herman S, Zaiss M, Franz S, Polzer K, Zwerina J, Herrmann M, Smolen J, Schett G: CTLA-4 directly inhibits osteoclast formation. Ann Rheum Dis. 2008;67(11): 1603-9
Zaiss MM, Schett G: Potential involvement of TRAIL in Treg cell-mediated osteoclast suppression: comment on the article by Zaiss et al - Reply Arthritis Rheum. 2008;58(6): 1887-1888
Zaiss MM, Axmann R, Zwerina J, Polzer K, Gückel E, Skapenko A, Schulze-Koops H, Horwood N, Cope A, Schett G: Treg cells suppress osteoclast formation: A new link between the immune system and bone. Arthritis Rheum. 2007;56(12): 4104-12

Prof. Dr. M. Zaiss

Publikationen: Prof. Dr. rer. nat. M. Zaiss

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