Prof. Dr. S. Uderhardt

Publications: Prof. Dr. med. S. Uderhardt

Uderhardt S, Ackermann JA, Fillep T, Hammond VJ, Willeit J, Santer P, Mayr M, Biburger M, Miller M, Zellner KR, Stark K, Zarbock A, Rossaint J, Schubert I, Mielenz D, Dietel B, Raaz-Schrauder D, Ay C, Gremmel T, Thaler J, Heim C, Herrmann M, Collins PW, Schabbauer G, Mackman N, Voehringer D, Nadler JL, Lee JJ, Massberg S, Rauh M, Kiechl S, Schett G, O'Donnell VB, Krönke G: (2017) Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease. J Exp Med. 2017;214(7): 2121-2138
Pfeifle R, Rothe T, Ipseiz N, Scherer HU, Culemann S, Harre U, Ackermann JA, Seefried M, Kleyer A, Uderhardt S, Haugg B, Hueber AJ, Daum P, Heidkamp GF, Ge C, Böhm S, Lux A, Schuh W, Magorivska I, Nandakumar KS, Lönnblom E, Becker C, Dudziak D, Wuhrer M, Rombouts Y, Koeleman CA, Toes R, Winkler TH, Holmdahl R, Herrmann M, Blüml S, Nimmerjahn F, Schett G, Krönke G: (2017) Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease. Nat Immunol. 2017;18(1): 104-113
Lauder SN, Allen-Redpath K, Slatter DA, Aldrovandi M, O'Connor A, Farewell D, Percy CL, Molhoek JE, Rannikko S, Tyrrell VJ, Ferla S, Milne GL, Poole AW, Thomas CP, Obaji S, Taylor PR, Jones SA, de Groot PG, Urbanus RT, Hörkkö S, Uderhardt S, Ackermann J, Vince Jenkins P, Brancale A, Krönke G, Collins PW, O'Donnell VB: (2017) Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis. Sci Signal. 2017;10(507)
Beyer C, Huang J, Beer J, Zhang Y, Palumbo-Zerr K, Zerr P, Distler A, Dees C, Maier C, Munoz L, Krönke G, Uderhardt S, Distler O, Jones S, Rose-John S, Oravecz T, Schett G, Distler JH: (2015) Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages. Ann Rheum Dis. 2015;74(6): 1317-24
Rothe T, Gruber F, Uderhardt S, Ipseiz N, Rössner S, Oskolkova O, Blüml S, Leitinger N, Bicker W, Bochkov VN, Yamamoto M, Steinkasserer A, Schett G, Zinser E, Krönke G: (2015) 12/15-Lipoxygenase-mediated enzymatic lipid oxidation regulates DC maturation and function. J Clin Invest. 2015;125(5): 1944-54
Beyer C, Beer J, Palumbo-Zer K, Zerr P, Distler A, Dees C, Munoz L, Kroenke G, Uderhardt S, Distler O, Ovarecz T, Schett G, Distler J: (2014) ACTIVATION OF LIVER X RECEPTORS INHIBITS EXPERIMENTAL FIBROSIS BY INTERFERING WITH INTERLEUKIN-6 RELEASE FROM MACROPHAGES Clin Exp Rheumatol. 2014;32 81(2): S65-S65
Ipseiz N, Uderhardt S, Scholtysek C, Steffen M, Schabbauer G, Bozec A, Schett G, Krönke G: (2014) The nuclear receptor Nr4a1 mediates anti-inflammatory effects of apoptotic cells. J Immunol. 2014;192(10): 4852-8
Lin NY, Beyer C, Giessl A, Kireva T, Scholtysek C, Uderhardt S, Munoz LE, Dees C, Distler A, Wirtz S, Krönke G, Spencer B, Distler O, Schett G, Distler JH: (2013) Autophagy regulates TNF?-mediated joint destruction in experimental arthritis. Ann Rheum Dis. 2013;72(5): 761-8
Lauber K, Keppeler H, Munoz LE, Koppe U, Schröder K, Yamaguchi H, Krönke G, Uderhardt S, Wesselborg S, Belka C, Nagata S, Herrmann M: (2013) Milk fat globule-EGF factor 8 mediates the enhancement of apoptotic cell clearance by glucocorticoids. Cell Death Differ. 2013;20(9): 1230-40
Scholtysek C, Katzenbeisser J, Fu H, Uderhardt S, Ipseiz N, Stoll C, Zaiss MM, Stock M, Donhauser L, Böhm C, Kleyer A, Hess A, Engelke K, David JP, Djouad F, Tuckermann JP, Desvergne B, Schett G, Krönke G: (2013) PPAR?/? governs Wnt signaling and bone turnover. Nat Med. 2013;19(5): 608-13
Krönke G, Reich N, Scholtysek C, Akhmetshina A, Uderhardt S, Zerr P, Palumbo K, Lang V, Dees C, Distler O, Schett G, Distler JH: (2012) The 12/15-lipoxygenase pathway counteracts fibroblast activation and experimental fibrosis. Ann Rheum Dis. 2012;71(6): 1081-7
Uderhardt S, Herrmann M, Oskolkova O, Aschermann S, Bicker W, Sarter K, Frey B, Rothe T, Voll R, Nimmerjahn F, Bochkov VN, Schett G, Kronke G: (2012) 12/15-LIPOXYGENASE ORCHESTRATES THE CLEARANCE OF APOPTOTIC CELLS AND MAINTAINS IMMUNOLOGIC TOLERANCE Ann Rheum Dis. 2012;71 1: S2
Uderhardt S, Rothe T, Zinser E, Oskolkova O, Herrmann M, Steinkasserer A, Bochkov V, Schett G, Kronke G: (2012) Enzymatic Lipid Oxidation Contributes to the Maintenance of Self-Tolerance by Regulating Antigen Clearance and Dendritic Cell Function. Arthritis Rheum. 2012;64 S(10): S462-S462
Uderhardt S, Herrmann M, Oskolkova OV, Aschermann S, Bicker W, Ipseiz N, Sarter K, Frey B, Rothe T, Voll R, Nimmerjahn F, Bochkov VN, Schett G, Krönke G: (2012) 12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance. Immunity. 2012;36(5): 834-46
Rothe T, Zinser E, Rossner S, Uderhardt S, Bochkov V, Oskolkova O, Schett G, Steinkasserer A, Kronke G: (2012) 12/15-lipoxygenase-mediated lipid oxidation regulates maturation of dendritic cells Immunology. 2012;137 1: 465-465
Uderhardt S, Krönke G: (2012) 12/15-lipoxygenase during the regulation of inflammation, immunity, and self-tolerance. J Mol Med. 2012;90(11): 1247-56
Uderhardt S, Diarra D, Katzenbeisser J, David JP, Zwerina J, Richards W, Kronke G, Schett G: (2010) Blockade of Dickkopf (DKK)-1 induces fusion of sacroiliac joints. Ann Rheum Dis. 2010;69(3): 592-7
Scholtysek C, Uderhardt S, Schett G, Kronke G: (2010) NR4A1 MODULATES THE INFLAMMATORY RESPONSE DURING MURINE EXPERIMENTAL ARTHRITIS Ann Rheum Dis. 2010;69 Suppl. : A91 -
Krönke G, Uderhardt S, Kim KA, Stock M, Scholtysek C, Zaiss MM, Surmann-Schmitt C, Luther J, Katzenbeisser J, David JP, Abdollahi-Roodsaz S, Tran K, Bright JM, Binnerts ME, Akhmetshina A, Böhm C, Distler JH, Joosten LA, Schett G, Abo A: (2010) R-spondin 1 protects against inflammatory bone damage during murine arthritis by modulating the Wnt pathway. Arthritis Rheum. 2010;62(8): 2303-12
Schett G, Stolina M, Dwyer D, Zack D, Uderhardt S, Krönke G, Kostenuik P, Feige U: (2009) Tumor necrosis factor alpha and RANKL blockade cannot halt bony spur formation in experimental inflammatory arthritis. Arthritis Rheum. 2009;60(9): 2644-54
Krönke G, Uderhardt S, Katzenbeisser J, Schett G: (2009) The 12/15-lipoxygenase pathway promotes osteoclast development and differentiation. Autoimmunity. 2009;42(4): 383-5
Krönke G, Katzenbeisser J, Uderhardt S, Zaiss MM, Scholtysek C, Schabbauer G, Zarbock A, Koenders MI, Axmann R, Zwerina J, Baenckler HW, van den Berg W, Voll RE, Kühn H, Joosten LA, Schett G: (2009) 12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis. J Immunol. 2009;183(5): 3383-9
Kronke G, Uderhardt S, Zhao J, Ah-Kim K, Binnerts M, Katzenbeisser J, Schett G, Abo A: (2008) R-spondin 1 protects from bone loss in Htnf transgenic and ovariectomized mice Arthritis Rheum. 2008;58 Suppl. (9): S646-S646
Kronke G, Katzenbeisser J, Uderhardt S, Baum W, Axmann R, Zwerina J, Schett G: (2008) 12/15-lipoxygenase is involved in the limitation of inflammation and tissue damage in murine arthritis Wien Klin Wochenschr. 2008;120 Suppl.: 37-37

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Publications: Prof. Dr. med. S. Uderhardt

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